祝连彩 - 重庆大学 - 生物工程学院

个人简介

2009年毕业于重庆大学大学获生物医学工程专业博士学位。主持重庆市自然科学基金2项，参与国家新药创制专项项目2项、973前期专项资助项目1项、国家自然科学基金项目5项和重大横向项目1项等。获重庆市自然科学奖三等奖2项。在International Journal of Biological Macromolecules；PROTEIN SCIENCE；BMC Complementary and Alternative Medicine等SCI期刊发表论文70余篇，被他引1852次。获发明专利授权30余项（其中已转化或应用3项）。主讲《生物制药技术实验》、《生物工程综合大实验》、《蛋白质分离工程》、《生物制药综合创新实验》等本科生或研究生专业课程，指导重庆市优秀硕士论文1篇。

研究领域

1.蛋白质分子的理性设计与改造 2.天然药物分子的活性及作用机制研究 3.药物分子的生物合成与转化

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.[1]Pan Yinping,Zhu Liancai*,Tan Jun,Lou Deshuai,Wang Bochu*. Engineering the cofactor binding site of 7alpha-hydroxysteroid dehydrogenase for improvement of catalytic activity, thermostability, and alteration of substrate preference. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2024,258(1):128847. (IF 8.2) 2.[2]Dai Xianling, Kuang Qin, Sun Yan, Xu Minxuan, Zhu Liancai*, Ge Chenxu, Tan Jun*, Wang Bochu. Fisetin represses oxidative stress and mitochondrial dysfunction in NAFLD through suppressing GRP78-mediated endoplasmic reticulum (ER) stress[J]. Journal of Functional Foods, 2022, 90: 104954. (IF 5.6) 3.[3]Ge Chenxu, Tan Jun*, Dai Xianling , Kuang Qin, Zhong Shaoyu, Lai Lili, Yi Chao, Sun Yan, Luo Jing, Zhang Chufeng, Zhu Liancai*, Wang Bochu, Xu Minxuan*. Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK[J]. Nature Communications, 2022, 13(1): 5945. (IF 16.6) 4.[4]Shunlin Ji, Pan Yinping, Zhu Liancai*, Jun Tan, Shijing Tang, Qiong Yang, Zhi Zhang, Deshuai Lou, Bochu Wang*,A novel 7α-hydroxysteroid dehydrogenase: Magnesium ion significantly enhances its activity and thermostability, International Journal of Biological Macromolecules. 2021, 177:111-118. (IF 8.2) 5.[5]Shijing Tang, Pan Yinping, Deshuai Lou, Shunlin Ji, Zhu Liancai*, Jun Tan, Na Qi, Qiong Yang, Zhi Zhang, Biling Yang, Wenyan Zhao, andBochu Wang*. Structural and functional characterization of a novel acidophilic 7 alpha-hydroxysteroid dehydrogenase. PROTEIN SCIENCE. 2019, 28(5):910-919.(IF 8.0)