Bailey, Mark - University of Glasgow - School of Life Sciences

研究领域

Human genetics and molecular genetics: mapping and identification of disease genes in Mendelian and complex disorders; molecular pathology and gene therapy of human genetic disorders; Rett syndrome; Psychiatric disorders and psychological traits; Type 2 diabetes/obesity/body composition/performance; Ménière disease; gene family evolution; meme-gene co-evolution; evolution of the human brain

近期论文

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Celis-Morales, C. et al. (2017) Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants. American Journal of Clinical Nutrition, (doi:10.3945/ajcn.116.147231) (Early Online Publication) Hector, R. D., Dando, O., Ritakari, T. E., Kind, P. C., Bailey, M. E.S., and Cobb, S. R. (2017) Characterisation of Cdkl5 transcript isoforms in rat. Gene, 603, pp. 21-26. (doi:10.1016/j.gene.2016.12.001) (PMID:27940108) Gianfagna, F. et al. (2017) The role of neuromedin U in adiposity regulation. Haplotype analysis in European children from the IDEFICS Cohort. PLoS ONE, 12(2), e0172698. (doi:10.1371/journal.pone.0172698) (PMID:28235053) (PMCID:PMC5325300) Wyse, C. A. et al. (2017) Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277 168 workers in UK biobank. Annals of Medicine, (doi:10.1080/07853890.2017.1292045) (PMID:28166415) (Early Online Publication) Ross, P. D. et al. (2016) Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics, 25(20), pp. 4389-4404. (doi:10.1093/hmg/ddw269) (PMID:28173151) Lyall, D. M. et al. (2016) Alzheimer disease genetic risk factor APOE e4, and cognitive abilities in 111,739 UK Biobank participants. Age and Ageing, 45(4), pp. 511-517. (doi:10.1093/ageing/afw068) (PMID:27103599) Hector, R. D., Dando, O., Landsberger, N., Kilstrup-Nielsen, C., Kind, P. C., Bailey, M. E.S., and Cobb, S. R. (2016) Characterisation of CDKL5 transcript isoforms in human and mouse. PLoS ONE, 11(6), e0157758. (doi:10.1371/journal.pone.0157758) (PMID:27315173) (PMCID:PMC4912119) Smith, D.J. et al. (2016) Genome-wide analysis of over 106?000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21(6), pp. 749-757. (doi:10.1038/mp.2016.49) (PMID:27067015) Qi, Q. et al. (2015) Dietary intake, FTOGenetic variants, and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes, 64(7), pp. 2467-2476. (doi:10.2337/db14-1629) (PMID:25720386) Gadalla, K. K. E., Ross, P. D., Hector, R. D., Bahey, N. G., Bailey, M. E.S., and Cobb, S. R. (2015) Gene therapy for Rett syndrome: prospects and challenges. Future Neurology, 10(5), pp. 467-484. (doi:10.2217/fnl.15.29) Wardle, S. L., Bailey, M. E., Kilikevicius, A., Malkova, D., Wilson, R. H., Venckunas, T., and Moran, C. (2015) Plasma microRNA levels differ between endurance and strength athletes. PLoS ONE, 10(4), e0122107. (doi:10.1371/journal.pone.0122107) Ross, P. D., Gadalla, K. K. E., Riddell, J. S., Bailey, M. E. S., and Cobb, S. R. (2014) Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits. PLoS ONE, 9(11), e112889. (doi:10.1371/journal.pone.0112889) (PMID:25392929) Wang, G. et al. (2013) Association analysis of ACE and ACTN3 in elite caucasian and east Asian swimmers. Medicine and Science in Sports and Exercise, 45(5), pp. 892-900. (doi:10.1249/MSS.0b013e31827c501f) Gadalla, K.K.E. et al. (2013) Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice. Molecular Therapy, 21(1), pp. 18-30. (doi:10.1038/mt.2012.200) (PMID:23011033) (PMCID:PMC3536818) Celis-Morales, C. A., Ghouri, N., Bailey, M.E.S., Sattar, N., and Gill, J. M.R. (2013) Should physical activity recommendations be ethnicity-specific? Evidence from a cross-sectional study of south Asian and European men. PLoS ONE, 8(12), e82568. (doi:10.1371/journal.pone.0082568) Gianfagna, F. et al. (2013) Understanding the links among neuromedin U Gene, beta2-adrenoceptor gene and bone health: an observational study in European children. PLoS ONE, 8(8), e70632. (doi:10.1371/journal.pone.0070632) Celis-Morales, C. A., Perez-Bravo, F., Ibanez, L., Salas, C., Bailey, M. E.S., and Gill, J. M.R. (2012) Objective vs. self-reported physical activity and sedentary time: effects of measurement method on relationships with risk biomarkers. PLoS ONE, 7(5), e36345. (doi:10.1371/journal.pone.0036345) Weng, S.-M., Bailey, M. E.S., and Cobb, S. R. (2011) Rett syndrome: from bed to bench. Pediatrics and Neonatology, 52(6), pp. 309-316. (doi:10.1016/j.pedneo.2011.08.002) Gadalla, K.K.E., Bailey, M.E.S., and Cobb, S.R. (2011) MeCP2 and Rett syndrome: reversibility and potential avenues for therapy. Biochemical Journal, 439(1), pp. 1-14. (doi:10.1042/BJ20110648) Weng, S.-M., McLeod, F., Bailey, M.E.S., and Cobb, S.R. (2011) Synaptic plasticity deficits in an experimental model of Rett Syndrome: LTP saturation and its pharmacological reversal. Neuroscience, 180, pp. 314-321. (doi:10.1016/j.neuroscience.2011.01.061) Koni, A.C., Scott, R.A., Wang, G., Bailey, M.E.S., Peplies, J., Bammann, K., and Pitsiladis, Y.P. (2011) DNA yield and quality of saliva samples and suitability for large scale epidemiological studies in children. International Journal of Obesity, 35(Suppl.), S113-S118. Celis-Morales, C.A., Perez-Bravo, F., Iba?es, L., Sanzana, R., Hormazabal, E., Ulloa, N., Calvo, C., Bailey, M.E.S., and Gill, J.M.R. (2011) Insulin resistance in Chileans of European and indigenous descent: evidence for an ethnicity x environment interaction. PLoS ONE, 6(9), e24690. (doi:10.1371/journal.pone.0024690) Wilson, R.H., Moran, C.N., Cole, J., Pitsiladis, Y.P., and Bailey, M.E.S. (2010) Evolutionary history of the ADRB2 gene in humans. American Journal of Human Genetics, 86(3), pp. 490-493. (doi:10.1016/j.ajhg.2010.01.031) Neul, J.L. et al. (2010) Rett Syndrome: Revised diagnostic criteria and nomenclature. Annals of Neurology, 68(6), pp. 944-950. (doi:10.1002/ana.22124) Scott, R.A. et al. (2010) FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males. European Journal of Human Genetics, 18(12), pp. 1339-1343. (doi:10.1038/ejhg.2010.131)