MUTAPI, Francisca - University of Edinburgh - School of Biological Sciences

个人简介

1993-1997 DPhil (Biological Sciences), Linacre College, University of Oxford. 1997-1999 Postdoctoral Research Fellow, Prince Leopold Institute of Tropical Medicine, Antwerp. 1999-2000 Departmental Lecturer (Molecular Parasitology), Department of Zoology, University of Oxford. 2001-2002 University Lecturer (Comparative Epidemiology), Department of Clinical Veterinary Studies, University of Glasgow. 2002-2005 MRC Research Fellow, Institute of Cell, Animal and Population Biology, University of Edinburgh. 2005-Present RCUK Fellow (Infection and immunity), Institute of Immunology and Infection Research, University of Edinburgh.

近期论文

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Mitchell KM, Mutapi F, Savill NJ and Woolhouse ME. Protective immunity to Schistosoma haematobium infection is primarily an anti-fecundity response stimulated by the death of adult worms. Proc Natl Acad Sci U S A 2012; 109: 13347-13352. RATED EXCEPTIONAL by Faculty 1000 .Bourke CD, Nausch N, Rujeni N, Appleby LJ, Mitchell K, Midzi N, Mduluza T, Mutapi F. Integrated analysis of innate, Th1, Th2, Th17 and regulatory cytokines identifies changes in immune polarisation following treatment of human schistosomiasis. In press, J Infect Dis Bourke CD, Mutapi F, Photiou DMF, Poulsen LK, Kristensen B, Arnved J, Rønborg S, Roepstorff A, Thamsborg S, Kapel C, Melbye M, Bager P. Trichuris suis ova therapy for allergic rhinitis does not affect allergen-specific cytokine responses despite a parasite-specific cytokine response. In press, Clin and Exp Aller. 2012; DOI: 10.1111/j.1365-2222.2012.04063.x SELECTED AS EDITOR’S CHOICE, COVER MANUSCRIPT Nausch N, Bourke CD, Appleby LJ, Rujeni N, Lantz O, Trottein F, Midzi N, Mduluza T and Mutapi F. Proportions of CD4+ memory T cells are altered in individuals chronically infected with Schistosoma haematobium. Sci Rep 2012; 2: 472. Higon M, Cowan G, Nausch N, Cavanagh D, Oleaga A, Toledo R, Stothard JR, Antunez O, Marcilla A, Burchmore R and Mutapi F. Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni. Parasitology 2011; 138: 1607-1619 Mutapi F, Burchmore R, Mduluza T, Midzi N, Turner CM and Maizels RM. Age-related and infection intensity-related shifts in antibody recognition of defined protein antigens in a schistosome-exposed population. J Infect Dis 2008; 198: 167-175. Mutapi, F., Burchmore, R., Mduluza, T., Foucher, A., Harcus, Y., Nicoll, G., Midzi N., Turner, C.M., Maizels, R. (2005). Praziquantel treatment of people exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens. J Infect Dis 192: 1108-1118.