MILLAR, Andrew - University of Edinburgh - School of Biological Sciences

个人简介

1985-1988 University of Cambridge, BA Hons (I) in Genetics 1988-1994 The Rockefeller University, New York- Ph.D. 1994-1995 University of Virginia, NSF Centre for Biological Timing- LSRF post-doc Fellowship. 1996-2004 University of Warwick, Dept. of Biological Sciences- lecturer, reader, professor. 2002-2007 BBSRC Research Development Fellow 2003-2004 Programme Manager of the Interdisciplinary Programme for Cellular Regulation, with Dr. Nigel Burroughs (Maths). 2004-present University of Edinburgh, School of Biological Sciences - Professor of Systems Biology. 2007-2011 Director, Centre for Systems Biology at Edinburgh (CSBE) 2012-present Associate Director, SynthSys 2011-2013 Elected to EMBO Membership and Fellowship of the Royal Society and Royal Society of Edinburgh

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Pokhilko, A., Mas, P. & Millar, A. J. 2013 Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs. BMC Systems Biology. 7: 23. doi: 10.1186/1752-0509-7-23. SBML model in PlaSMo Highly accessed article. Gould, P. D., Ugarte, N., Domijan, M., Costa, M., Foreman, J., Macgregor, D., Rose, K., Griffiths, J., Millar, A. J., Finkenstadt, B., Penfield, S., Rand, D. A., Halliday, K. J. & Hall, A. J. W. 2013 Network balance via CRY signalling controls the Arabidopsis circadian clock over ambient temperatures. Molecular Systems Biology. 9: 650. doi: 10.1038/msb.2013.7. SBML model in PlaSMo. Ocone, A., Millar, A.J., and Sanguinetti, G. (2013). Hybrid regulatory models: a statistically tractable approach to model regulatory network dynamics. Bioinformatics. doi: 10.1093/bioinformatics/btt069. Adams, R. , Clark, A. , Yamaguchi, A. , Hanlon, N. , Tsorman, N. , Ali, S. , Lebedeva, G. , Goltsov, A. , Sorokin, A. , Akman, O. E. , Troein, C. , Millar, A. J. , Goryanin, I. & Gilmore, S. SBSI: An extensible distributed software infrastructure for parameter estimation in systems biology (2013) Bioinformatics. doi:10.1093/bioinformatics/btt023. Link Schaum, E. , Rost, B. , Millar, A. J. & Collins, S. (2013) Variation in plastic responses of a globally distributed picoplankton species to ocean acidification. Nature Climate Change 3, 298-302. Link van Ooijen G. and Millar A.J. (2012) Non-transcriptional oscillators in circadian timekeeping. Trends Biochem. Sci. . Online 20 August 2012. doi: 10.1016/j.tibs.2012.07.006 Link [review paper, peer-reviewed]. Frank Dondelinger, Simon Rogers, Maurizio Filippone, Roberta Cretella, Tim M. Palmer, Robert W. Smith, Andrew J. Millar and Dirk Husmeier (2012) Parameter Inference In Mechanistic Models Of Cellular Regulation And Signalling Pathways Using Gradient Matching. WCSB 2012, Ninth International workshop on computational systems biology, Finland. (accepted). Gerben van Ooijen, Kirsten Knox, Katalin Kis, Francois-Yves Bouget, Andrew J. Millar (2012) Genomic transformation of the picoeukaryote Ostreococcus tauri. J. Vis. Exp. 65: e4074. doi:10.3791/4074. Link Adams, R. R. , Tsorman, N. , Stratford, K. , Akman, O. E. , Gilmore, S. , Juty, N. , Le Novere, N. , Millar, A. J. & Millar, A. J. (2012) The Input Signal Step Function (ISSF), a Standard Method to Encode Input Signals in SBML Models with Software Support, Applied to Circadian Clock Models. Journal of Biological Rhythms. 27: 328-332. doi:10.1177/0748730412451077. Link Young Hun Song, Robert W. Smith, Benjamin J. To, Andrew J. Millar, Takato Imaizumi (2012) FKF1 conveys crucial timing information for CONSTANS stabilization in photoperiodic flowering. Science 336: 1045-1049. Online 25 May 2012. doi: 10.1126/science.1219644 Link Featured in: F1000Prime 4*. Multiple reviews. F1000.com/716497817 Edgar R.S.*, Green E.W.*, Zhao Y.*, van Ooijen G.*, Olmedo M.*, Qin X., Xu Y., Pan M., Valekunja E.K., Feeney K.A., Maywood E.S., Hastings M.H., Baliga N.S., Merrow M., Millar A.J., Johnson C.H., Kyriacou C.P., O'Neill J.S.**, Reddy A.B.** (2012) Peroxiredoxins are conserved markers of circadian rhythms. Nature 485: 459-464. Online 16 May 2012. doi: 10.1038/nature11088. Link. Corrigendum 8 Aug 2012. Link. Featured in: F1000Prime 6*. Multiple reviews. F1000.com/716597871 Ewen Callaway, A biological clock to wind them all, Nature News 16 May 2012. Debora MacKenzie, Biological clock began ticking 2.5 billion years ago, New Scientist 2865, 16 May 2012. Sarah Evert, Picking Apart Our Circadian Clock, Chemical & Engineering News, 90: 30. June 4, 2012. Andrew S.I. Loudon, Circadian Biology: A 2.5 Billion Year Old Clock, Current Biology 22: R570-R571. Ozgur E. Akman*, Steven Watterson, Andrew Parton, Nigel Binns, Andrew J. Millar** and Peter Ghazal** (2012) Digital clocks: simple Boolean models can quantitatively describe circadian systems. J R Soc Interface 9: 2365-82. Online 12 April. *corresponding author; **senior authors. doi: 10.1098/a€?rsif.2012.0080 Link Benedicte Wenden, David L. K. Toner, Sarah K. Hodge, Ramon Grima, Andrew J. Millar (2012) Spontaneous spatiotemporal waves of gene expression from biological clocks in the leaf. Proc. Natl. Acad. Sci. USA, 109: 6757-62. online 10 April. doi: 10.1073/pnas.1118814109. Link Featured in: F1000Prime 3*. Multiple reviews. F1000.com/716747960 Huang W, Perez-Garcia P, Pokhilko A, Millar AJ, Antoshechkin I, Riechmann JL, Mas P. (2012) Mapping the Core of the Arabidopsis Circadian Clock Defines the Network Structure of the Oscillator. Science 336: 75-59. Online Mar 8. doi: 10.1126/science.1219075 Link Featured in: F1000Prime 3*. Harmer S: 2012. F1000.com/14245972 Pokhilko A, Fernandez AP, Edwards KD, Southern MM, Halliday KJ, Millar AJ. (2012) The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops. Mol Syst Biol. 8: 574. doi: 10.1038/msb.2012 Link Featured in: Mol Syst Biol Featured Article, and Top Download. F1000Prime 3*. Harmer S: 2012. F1000.com/14247957