邓国宏 - 重庆大学

个人简介

陆军军医大学第一附属医院感染病科副主任，教授，博士生导师学习经历 1990.09-1994.06，第三军医大学，医学检验专业，学士 1996.09-1999.06，第三军医大学，微生物学专业，硕士 2001.09-2004.06 第三军医大学，传染病学专业，博士工作经历 1994.07-2000.08，第三军医大学，医学检验系，助教 2000.09-2004.08，第三军医大学，医学检验系，讲师 2004.09-2006.08，第三军医大学，第一附属医院感染病科，讲师 2006.09-2011.08，第三军医大学，第一附属医院感染病科，副研究员 2008.10-2009.10，英国帝国理工学院圣玛丽医院肝脏病科，访问学者 2011.09-至今，第三军医大学（陆军军医大学），第一附属医院感染病科，教授 2010.02-至今，第三军医大学（陆军军医大学），内科学（传染病），博士生导师成果：一、近五年发表第一作者/通讯作者SCI论文二、授权发明专利三、主持承担省部级及以上科研项目四、科技奖

研究领域

1. 肝病遗传学研究；2. 病毒感染重症化机制及防治

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. An inhibitor of leukotriene-A4 hydrolase from bat salivary glands facilitates virus infection. PNAS 2022 Mar 8;119(10):e2110647119( SCI, IF2021= 12.779 ) 2. Prevalence and clinical significance of serum sodium variability in patients with acute-on-chronic liver diseases: a prospective multicenter study in China. Hepatol Int 2022;16(1):183-194( SCI, IF2021= 9.029 ) 3. Role of LL‑37 in thrombotic complications in patients with COVID-19. Cellular and Molecular Life Sciences 2022;79(6):309( SCI, IF2021= 9.207 ) 4. Hepatitis B Virus Reactivation Increased the Risk of Developing Hepatic Failure and Mortality in Cirrhosis With Acute Exacerbation. Frontiers in Microbiology 2022;13:910549( SCI, IF2021= 6.064 ) 5. Causal effect of autoimmune liver diseases on cancer: Meta-analyses of cohort studies and Mendelian randomization study. Liver International 2022;42(10):2216-2226( SCI, IF2021= 8.754 ) 6. Identification of an Autoantibody Against ErbB-3-Binding Protein-1 in the Sera of Patients With Chronic Hepatitis B Virus Infection. Front Immunol 2021;12:640335( SCI, IF2021= 8.786 ) 7. SARS-CoV-2 quasispecies provides an advantage mutation pool for the epidemic variants. Microbiol Spectr 2021;9(1):e0026121( SCI, IF2021= 9.043 ) 8. Testosterone and estradiol as novel prognostic indicators for HBV-related acute-on-chronic liver failure. Frontiers in Medicine 2021;8:729030( SCI, IF2021= 5.058 ) 9. Impact of Hepatic Encephalopathy on Clinical Characteristics and Adverse Outcomes in rospective and Multicenter Cohorts of Patients With Acute-on-Chronic Liver Diseases. Frontiers in Medicine 2021;8:709884( SCI, IF2021= 5.058 ) 10. Cohort profile: a multicentre prospective validation cohort of the Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study. BMJ Open 2021;11(1):e037793( SCI, IF2021= 3.006 ) 11. Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix. Journal of Visualized Experiments 2021 Oct 20;(176).doi: 10.3791/62387( SCI, IF2021= 1.424 ) 12. TNF-α/IFN-γ profile of HBV-specific CD4 T cells is associated with liver damage and viral clearance in chronic HBV infection. Journal of Hepatology 2020;72(1):45-56( SCI, IF2021= 30.083) 13. Shorter incubation period is associated with severe disease progression in patients with COVID-19. Virulence 2020;11(1):1443-1452( SCI, IF2021=5.428) 14. TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2. Drug Dev Res 2020;81:1004-1018( SCI, IF2021=5.004) 15. Copy number gain of pro-inflammatory genes in patients with HBV-related acute-on-chronic liver failure. BMC Med Genomics 2020;13(1):180( SCI, IF2021=3.622) 16. A patient with glycogen storage disease type Ia combined with chronic hepatitis B infection: a case report. BMC Med Genet 2019;20(1):85( SCI, IF2021= 2.023) 17. Genome-wide association study identifies HLA-DR variants confering risk of HBV-related acute-on-chronic liver failure. Gut 2018;67(4):757-766 ( SCI, IF2021= 31.793 ) 18. A novel mutation in the BCHE gene and phenotype identified in a child with low butyrylcholinesterase activity: a case report. BMC Med Genet 2018;19(1):58 ( SCI, IF2021= 2.023) 19. β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development. Sci Rep 2017;7(1):13404( SCI, IF2021= 4.996 ) 20. Effectiveness of PIVKA-II in the detection of hepatocellular carcinoma based on real-world clinical data. BMC Cancer 2017;17(1):608( SCI, IF2021= 4.638) 21. Stability of Chronic Hepatitis-Related Parameters in Serum Samples After Long-Term Storage. Biopreserv Biobank 2017;15(3):211-219( SCI, IF2021= 2.256 )