Welch, Andy - University of Aberdeen - School of Medicine, Medical Sciences and Nutrition

个人简介

Professor Welch graduated from the University of Southampton with a first class honours degree in Physics in 1987 and went on to obtain a PhD in Medical Physics at the University of London (Royal Marsden Hospital) in 1990. After a brief spell in industry (working as a systems analyst for an oil company) he returned to academia, taking up a postdoctoral position and then a faculty position at the University of Utah. In 1997 he returned to the UK, as a lecturer, senior lecturer then Professor at the University of Aberdeen.

研究领域

My research has focussed on the tomographic radiotracer imaging techniques of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) as well as Computed Tomography (CT) in general. I am particularly interested in the development of novel hardware and software to address specific applications. These include clinical applications, preclinical applications and applications in engineering and geosciences.

近期论文

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Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, AE., Elmore, CS., Sharma, P. & Zanda, M. (2017). 'Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters'. Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 963-976. DOI: [ONLINE] DOI: 10.1016/J.BMC.2016.12.008 Plucińska, K., Dekeryte, R., Koss, D., Shearer, K., Mody, N., Whitfield, PD., Doherty, MK., Mingarelli, M., Welch, AE., Riedel, G., Delibegovic, M. & Platt, B. (2016). 'Neuronal human BACE1 knock-in induces systemic diabetes in mice'. Diabetologia, vol 59, no. 7, pp. 1513-1523. DOI: [ONLINE] DOI: 10.1007/S00125-016-3960-1 [ONLINE] AURA: ART_3A10.1007_2FS00125_016_3960_1.PDF Bain, GH., Collie-Duguid, E., Murray, GI., Gilbert, FJ., Denison, A., McKiddie, F., Ahearn, T., Fleming, I., Leeds, J., Phull, P., Park, K., Nanthakumaran, S., Grabsch, HI., Tan, P., Welch, A., Schweiger, L., Dahle-Smith, A., Urquhart, G., Finegan, M., Matula, KM. & Petty, RD. (2014). 'Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas'. British Journal of Cancer, vol 110, no. 6, pp. 1525-1534. DOI: [ONLINE] DOI: 10.1038/BJC.2014.45 Shaikh, S., Welch, A., Ramalingam, SL., Murray, A., Wilson, HM., McKiddie, F. & Brittenden, J. (2014). 'Comparison of fluorodeoxyglucose uptake in symptomatic carotid artery and stable femoral artery plaques'. British Journal of Surgery, vol 101, no. 3, pp. 363-370. DOI:[ONLINE] DOI: 10.1002/BJS.9403 Lobley, GE., Johnstone, AM., Fyfe, C., Horgan, GW., Holtrop, G., Bremner, DM., Broom, I., Schweiger, L. & Welch, A. (2014). 'Glucose uptake by the brain on chronic high-protein weight-loss diets with either moderate or low amounts of carbohydrate'. British Journal of Nutrition, vol 111, no. 4, pp. 586-597. DOI: [ONLINE] DOI: 10.1017/S0007114513002900 [ONLINE] AURA: BJN_2013_019620RR_REVISED_FINAL_REFS_NO_FIGS.DOCX [ONLINE] AURA: BJN_2013_019620_FIGURE_1.DOCX [ONLINE] AURA: BJN_2013_019620_FIGURE_2.DOCX Welch, A., Mingarelli, M., Riedel, G. & Platt, B. (2013). 'Mapping Changes in Mouse Brain Metabolism with PET/CT'. Journal of Nuclear Medicine, vol 54, no. 11, pp. 1946-1953. DOI: [ONLINE] DOI: 10.2967/JNUMED.113.121509 Owen, C., Czopek, A., Agouni, A., Grant, L., Judson, R., Lees, EK., McIlroy, GD., G?ransson, O., Welch, A., Bence, KK., Kahn, BB., Neel, BG., Mody, N. & Delibegovic, M. (2012). 'Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis'. PLoS ONE, vol 7, no. 2, e32700. DOI: [ONLINE] DOI: 10.1371/JOURNAL.PONE.0032700 [ONLINE] AURA: DELIBEGOVIC_ADIPOSE1BKO_PLOS_2012.PDF Platt, B., Drever, B., Koss, D., Stoppelkamp, S., Jyoti, A., Plano, A., Utan, A., Merrick, G., Ryan, D., Melis, V., Wan, H., Mingarelli, M., Porcu, E., Scrocchi, L., Welch, A. & Riedel, G. (2011). 'Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1'. PloS one, vol 6, no. 11, e27068. DOI: [ONLINE] DOI: 10.1371/JOURNAL.PONE.0027068 [ONLINE] AURA: PLATT_ET_AL_2011_PLOSONE.PDF [LINK] HTTP://WWW.PLOSONE.ORG/ARTICLE/INFO%3ADOI%2F10.1371%2FJOURNAL.PONE.0027068 Platt, B., Welch, A. & Riedel, G. (2011). 'FDG-PET imaging, EEG and sleep phenotypes as translational biomarkers for research in Alzheimer's disease'. Biochemical Society Transactions, vol 39, no. 4, pp. 874-880. [ONLINE] AURA: FDG_PET_IMAGING.PDF Suttie, S., McAteer, D., Sheehan, M., Nicolson, M., Schweiger, L., Hammonds, S., Smith, T., Welch, A. & Park, K. (2010). 'F-18-FDG and C-11-choline positron emission tomography in human esophago-gastric cancer: prediction of response to therapy'. World Journal of Oncology, vol 1, no. 2, pp. 66-77. DOI: [ONLINE] DOI: 10.4021/WJON2010.04.201W [ONLINE] AURA: F_18_FDG_AND_C_11_CHOLINE.PDF