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王品美 副教授 博士生导师 收藏 完善纠错
浙江大学    海洋学院

个人简介

2005年本科毕业于浙江大学生命科学学院生物科学系,之后免试推荐在浙江大学生命科学学院微生物系攻读博士学位,2010年博士毕业后在浙江大学生命科学学院开展博士后研究,2012年7月到浙江大学海洋工程与科学系工作,2013-2014年到美国威斯康星麦迪逊分校医学微生物与免疫系访问,2016年在浙江大学海洋学院晋升为副教授和博士生导师。 主要研究领域为海洋微生物和微生物生物合成学,重点研究模式微生物酿酒酵母、海洋微生物遗传代谢相关功能基因的作用及分子调控机制,构建酵母、曲霉为底盘生物,挖掘海洋微生物次级代谢生物合成途径,激活次级代谢生物合成沉默基因簇的表达,获得新型活性物质,应用于环境治理、医药及工农业等领域。迄今共发表SCI论文19篇,主持国家自然科学基金、浙江省项目等4项。

研究领域

· 海洋微生物资源 · 微生物生物合成研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Li X, Xu JZ, Wang WJ, Chen YW, Zheng DQ, Di YN, Li P, Wang PM*, and Li YD*, Genome Sequencing and Evolutionary Analysis of Marine Gut Fungus Aspergillus sp. Z5 from Ligia oceanica. Evol Bioinform Online, 2016; 12: 1-4. Pubmed Record 2. Wang P-M, Choera T, Wiemann P, Pisithkul T, Amador-Noguez D, and Keller NP*, TrpE feedback mutants reveal roadblocks and conduits towards increasing secondary metabolism in Aspergillus fumigatus. Fungal Genetics and Biology, 2016; 89: 102-113. Pubmed Record 3. Wang P, Zhao S, Liu Y, Ding W, Qiu F, and Xu J*, Asperginine, an Unprecedented Alkaloid from the Marine-derived Fungus Aspergillus sp. Natural Product Communications, 2015; 10: 1363-1364. Pubmed Record 4. Li O, Qian CD, Zheng DQ, Wang PM, Liu Y, Jiang XH, and Wu XC*, Two UDP-glucuronic acid decarboxylases involved in the biosynthesis of a bacterial exopolysaccharide in Paenibacillus elgii. Appl Microbiol Biotechnol, 2015; 99: 3127-39. Pubmed Record 5. Zhang K, Tong M, Gao K, Di Y, Wang P, Zhang C, Wu X*, and Zheng D*, Genomic reconstruction to improve bioethanol and ergosterol production of industrial yeast Saccharomyces cerevisiae. J Ind Microbiol Biotechnol, 2015; 42: 207-18. Pubmed Record 6. Wang PM, Zheng DQ, Chi XQ, Li O, Qian CD, Liu TZ, Zhang XY, Du FG, Sun PY, Qu AM, and Wu XC*, Relationship of trehalose accumulation with ethanol fermentation in industrial Saccharomyces cerevisiae yeast strains. Bioresour Technol, 2014; 152: 371-6. Pubmed Record 7. Li O, Liu A, Lu C, Zheng DQ, Qian CD, Wang PM, Jiang XH, and Wu XC*, Increasing viscosity and yields of bacterial exopolysaccharides by repeatedly exposing strains to ampicillin. Carbohydr Polym, 2014; 110: 203-8. Pubmed Record 8. Liu Y, Zhao S, Ding W, Wang P, Yang X, and Xu J*, Methylthio-aspochalasins from a marine-derived fungus Aspergillus sp. Mar Drugs, 2014; 12: 5124-31. Pubmed Record 9. Zheng DQ, Chen J, Zhang K, Gao KH, Li O, Wang PM, Zhang XY, Du FG, Sun PY, Qu AM, Wu S, and Wu XC*, Genomic structural variations contribute to trait improvement during whole-genome shuffling of yeast. Appl Microbiol Biotechnol, 2014; 98: 3059-70. Pubmed Record 10. Li O, Lu C, Liu A, Zhu L, Wang PM, Qian CD, Jiang XH, and Wu XC*, Optimization and characterization of polysaccharide-based bioflocculant produced by Paenibacillus elgii B69 and its application in wastewater treatment. Bioresour Technol, 2013; 134: 87-93. Pubmed Record 11. Zheng DQ, Liu TZ, Chen J, Zhang K, Li O, Zhu L, Zhao YH, Wu XC*, and Wang PM*, Comparative functional genomics to reveal the molecular basis of phenotypic diversities and guide the genetic breeding of industrial yeast strains. Appl Microbiol Biotechnol, 2013; 97: 2067-76. Pubmed Record 12. Tao X, Zheng D, Liu T, Wang P, Zhao W, Zhu M, Jiang X, Zhao Y, and Wu X*, A novel strategy to construct yeast Saccharomyces cerevisiae strains for very high gravity fermentation. PloS one, 2012; 7: e31235. Pubmed Record 13. Wang PM, Zheng DQ, Liu TZ, Tao XL, Feng MG, Min H, Jiang XH, and Wu XC*, The combination of glycerol metabolic engineering and drug resistance marker-aided genome shuffling to improve very-high-gravity fermentation performances of industrial Saccharomyces cerevisiae. Bioresour Technol, 2012; 108: 203-10. Pubmed Record 14. Zheng DQ, Wang PM, Chen J, Zhang K, Liu TZ, Wu XC*, Li YD, and Zhao YH, Genome sequencing and genetic breeding of a bioethanol Saccharomyces cerevisiae strain YJS329. BMC Genomics, 2012; 13: 479. Pubmed Record 15. Wang PM, Zheng DQ, Ding R, Chi XQ, Tao XL, Min H, and Wu XC*, Improvement of ethanol production in Saccharomyces cerevisiae by hetero-expression of GAPN and FPS1 deletion. Journal of Chemical Technology and Biotechnology, 2011; 86: 1205-1210. Pubmed Record 16. Wang PM, Wu X-C*, Chi X-Q, Li Y-D, Zheng D-Q, Ding R, and Min H, Development and application of RAPD-SCAR markers to identify intra-species hybrids of industrial Saccharomyces cerevisiae. World Journal of Microbiology and Biotechnology, 2011; 27: 185-188. Pubmed Record 17. Zheng DQ, Wu XC*, Tao XL, Wang PM, Li P, Chi XQ, Li YD, Yan QF, and Zhao YH, Screening and construction of Saccharomyces cerevisiae strains with improved multi-tolerance and bioethanol fermentation performance. Bioresour Technol, 2011; 102: 3020-7. Pubmed Record 18. Zheng D-Q, Wu X-C, Wang PM, Chi X-Q, Tao X-L, Li P, Jiang X-H, and Zhao Y-H, Drug resistance marker-aided genome shuffling to improve acetic acid tolerance in Saccharomyces cerevisiae. Journal of industrial microbiology & biotechnology, 2011; 38: 415-422. Pubmed Record 19. Wu X, Chi X, Wang P, Zheng D, Ding R, and Li Y*, The evolutionary rate variation among genes of HOG-signaling pathway in yeast genomes. Biology direct, 2010; 5: 46. Pubmed Record

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