段博 - 苏州大学 - 生命科学学院

个人简介

段博，本科及博士毕业于北京大学，随后在北京大学核磁共振中心从事博士后研究工作，2022年7月入职苏州大学基础医学与生物科学学院。长期致力于利用核磁共振技术研究蛋白质的结构以及蛋白质和其他分子的相互作用机制，在JACS, Nucleic Acids Res, Mol Biol Evol等国际学术期刊上发表了多篇文章。获得国家自然科学基金委青年科学基金项目、北京分子科学国家中心BMS Junior Fellow项目的支持。教育经历本科,2007.9-2011.7,化学,北京大学,理学学士博士,2012.9-2018.1,分析化学,北京大学,理学博士工作经历 2018.1-2022.6,北京大学化学与分子工程学院,博士后 2022.7-今,苏州大学基础医学与生物科学学院,特聘副教授

研究领域

.核磁共振波谱学 2.蛋白质/DNA相互作用机制 3.酶的动态特性及别构调控机制

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1、Selective Nonmethylated CpG DNA Recognition Mechanism of Cysteine Clamp Domains,Journal of the American Chemical Society,2021,Bo Duan,Dihong Fu,Chaoqun Zhang,Pengfei Ding,Xianzhi Dong,Bin Xia,143(20):7688-7697,1 2、Xenogeneic Silencing and Bacterial Genome Evolution: Mechanisms for DNA Recognition Imply Multifaceted Roles of Xenogeneic Silencers,Molecular Biology and Evolution,2021,Bo Duan,Pengfei Ding,William Wiley Navarre,Jun Liu,Bin Xia,38(10):4135-4148,1 3、How Bacterial Xenogeneic Silencer Rok Distinguishes Foreign from Self DNA in Its Resident Genome,Nucleic Acids Research,2018,Bo Duan,Pengfei Ding,Timothy R Hughes,William Wiley Navarre,Jun Liu,Bin Xia,46(19):10514-10529 4、The DNA Recognition Motif of GapR Has an Intrinsic DNA Binding Preference towards AT-rich DNA,Molecules,2021,Qian Huang,Bo Duan,Zhi Qu,Shilong Fan,Bin Xia,26(19):5776 5、DNA binding mechanism of WhiB4 from Mycobacterium tuberculosis,Magnetic Resonance Letters,2022,Qiran Zhai,Bo Duan,Chen Lin,Bin Xia,2(1):17-27 6、Is amyloid fibrillation related to 3D domain swapping for the C-terminal domain of SARS-CoV main protease,International Journal of Biological Macromolecules,2022,Zhiliang Yuan,Zhi Qu,Bo Duan,Tianyi Wang,Jiajun Xu,Bin Xia,197:68-76 7、1H, 13C, and 15N resonance assignments of reduced apo-WhiB4 from Mycobacterium tuberculosis,Biomolecular NMR Assignments,2021,Qiran Zhai,Chen Lin,Bo Duan,Lu Zhang,Bin Xia,15(1):99-101 8、GapR binds DNA through dynamic opening of its tetrameric interface,Nucleic Acids Research,2020,Qian Huang,Bo Duan,Xianzhi Dong,Shilong Fan,Bin Xia,48(16):9372-9386 9、Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells,Journal of Biological Chemistry,2019,Yangjie Liao,Bo Duan,Yufei Zhang,Xinmin Zhang,Bin Xia,294(52):20009-20023