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个人简介

Since 2021, Associate Professor (Tenure-track PI), Frontiers Science Center for Transformative Molecules(FSCTM), Shanghai Jiao Tong University 2018-2021, Postdoctoral research with Prof. Frank Glorius, Westfälische Wilhelms-Universität Münster 2014-2018, Ph.D. (summar cum laude) with Prof. Eric Meggers, Philipps-Universität Marburg 2011-2014, Master with Prof. Eric Meggers & Prof. Lei Gong, Xiamen University 2007-2011, Bachelor, Northwest A&F University 2011年本科毕业于西北农林科技大学,之后分别于厦门大学和德国马尔堡大学获得硕士 (2014年,导师:Prof. Eric Meggers与龚磊教授) 及博士学位 (2018年,导师:Prof. Eric Meggers)。2018至2021年,于德国明斯特大学开展博士后研究,合作导师为德国科学院院士 Prof. Frank Glorius。2021年12月加入上海交通大学教育部变革性分子前沿科学中心,任课题组长,长聘教轨副教授,博士生导师。研究方向为金属有机化学和不对称合成化学。以通讯作者或第一作者身份发表高水平研究论文多篇 ,包括 Science 1 篇,Nat. Catal. 1 篇,Nat. Commun. 1篇, Nat. Protoc. 1 篇,Chem 1 篇, J. Am. Chem. Soc. 2 篇, Angew. Chem. Int. Ed. 4 篇。研究成果先后被 Science、 Chem、 Synfacts、 ChemistryViews、C&EN 和 EurekAlert!等刊物及科技媒体评述和报道。先后获得厦门大学优秀毕业生 (2014)、国家优秀自费留学生奖学金 (2018)、 马尔堡大学优秀博士论文奖 (2018, 全校六名) 等荣誉,曾入选上海市领军人才计划(海外)(2021)和国家海外高层次青年人才引进计划(2021)。

研究领域

基于金属中心手性的金属有机化学 新型不对称催化体系的开发及应用 药物小分子的高效构建及精准编辑

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Ir(III) Pincer Complex with Solo Coordinatively Active Site as a Surrogate for Half-Sandwich Catalysts: Enabling Asymmetric Acylnitrenoid Transfer and Structure-Activity Relationship Studies. J. Am. Chem. Soc. 2025, doi:10.1021/jacs.5c12730. Chu, Y.-P.†; Xu, Z.-H.†; Zhao, J.; Wang, C.; Daniliuc C. G.; Ma, J.* ( Accessing N-Unprotected Unnatural α-Amino Acid Esters by Half-Sandwich Chiral-at-Ruthenium Aldehyde Catalysis: Scope and Mechanistic Study. Angew. Chem. Int. Ed. 2025, e202510811. Chen, G.†; Morais, G. N.†; Liang H.; Zhao, J.; Wang, C.; Chen, S.*; Ma, J.* Half-Sandwich Ru(II) Complexes Featuring Metal-Centered Chirality: Configurational Stabilization by Ligand Design, Preparation via Kinetic Resolution, and Application in Asymmetric Catalysis. J. Am. Chem. Soc. 2025, 147, 6825. Liang, H.†; Morais, G. N.†; Chen, G.†; Tang, W.; Zhao, J.; Wang, C.; Houk, K. N.; Chen, S.*; Ma, J.* Asymmetric Synthesis of Stereogenic-at-Iridium(III) Complexes through Pd-Catalyzed Kinetic Resolution. Nat. Commun. 2025, 16, 1177.Chu, Y.-P.; Yue, X.-L.; Liu, D.-H.; Wang C.; Ma, J.* Reshaping Quinolines by Single-Electron-Transfer-Triggered Dearomatization. Chem 2024, 10, 3529.Chu, Y.-P.; Ma, J.* Programmable Modular Assembly of Homochiral Ir(III)-Metallohelices to Reverse Metallodrug Resistance by Inhibiting CDK1. Angew. Chem. Int. Ed. 2024, 64, e202419292. Li, X.*; Zhao, X.; Wang, X.; Xiong, A.; Wang, Z.; Shi, Z.; Zhang, J.; Wang, H.; Wei, W.; He, C.; Ma, J.; Guo, Z.; Duan, C.*; Zhao, J.*; Wang, X.* 八面体金属中心手性络合物的合成研究进展. 中国基础科学, 2024, 26. DOI:10.3969/j.issn.1009-2412.2024.05.005. 楚云鹏, 马佳佳* Recent Advances in Dearomative Partial Reduction of Benzenoid Arenes. Angew. Chem. Int. Ed. 2024, 63, e202402819.Liu, D.-H.; Ma, J.* Late-Stage Saturation of Drug Molecules. J. Am. Chem. Soc. 2024, 146, 11866. Liu, D.-H.;† Pflüger P. M.;† Outlaw A.;† Lückemeier L.; Zhang F.; Regan C.; Nodeh H. R.; Cernak T.*; Ma, J.*; Glorius F.* Chemoselective Quinoline and Isoquinoline Reduction by Energy Transfer Catalysis Enabled Hydrogen Atom Transfer. Angew. Chem. Int. Ed. 2023, 62, e202312203. Liu, D.-H.;† Nagashima, K.;† Liang, H.; Yue, X.-L.; Chu, Y.-P.; Chen, S.*; Ma, J.* Ma, J.;† Chen, S.;† Bellotti, P.;† Wagener, T.; Daniliuc, C.; Houk, K. N.; Glorius, F. Facile access to fused 2D/3D rings via intermolecular cascade dearomative [2+2] cycloaddition/rearrangements of quinolines with alkenes. Nat. Catal. 2022, 5, 405. (†Equal contribution) Ma, J.;† Chen, S.;† Bellotti, P.;† Guo, R.; Schäfer, F.; Heusler, A., Zhang, X., Daniliuc, C., Brown, M. K.; Houk, K. N.; Glorius, F. Photochemical intermolecular dearomative cycloaddition of bicyclic azaarenes with alkenes. Science 2021, 371, 1338. (†Equal contribution) Huang, H.-M.; Bellotti, P.; Ma, J.; Dalton, T.; Glorius, F. Bifunctional reagents in organic synthesis. Nat. Rev. Chem. 2021, 5, 301. Ma, J.; Schäfers, F.; Daniliuc, C.; Bergander, K.; Strassert, C. A.; Glorius, F. Gadolinium photocatalysis: Dearomative [2+2] cycloaddition/ring-expansion sequence with indoles. Angew. Chem. Int. Ed. 2020, 59, 9639. Ma, J.; Strieth-Kalthoff, F.; Dalton, T.; Freitag, M.; Schwarz, J. L.; Bergander, K.; Daniliuc, C.; Glorius, F. Direct dearomatization of pyridines via an energy-transfer-catalyzed intramolecular [4+2] cycloaddition. Chem 2019, 5, 2854. (Cover art, 封面文章) Patra, T.; Mukherjee, S.; Ma, J.; Strieth-Kalthoff, F.; Glorius, F. Visible-light-photosensitized aryl and alkyl decarboxylative functionalization reactions. Angew. Chem. Int. Ed. 2019, 58, 10514. Ma, J.; Lin J.; Zhao L.; Harms K.; Marsch M.; Xie X.; Meggers, E. Synthesis of beta-substituted gama-aminobutyric acid derivatives via enantioselective photoredox catalysis. Angew. Chem. Int. Ed. 2018, 57, 11193. Ma, J.;† Zhang, X.;† Huang, X.; Luo, S.; Meggers, E. Preparation of chiral-at-metal catalysts and their use in asymmetric photoredox chemistry. Nat. Protoc. 2018, 13, 605. (†Equal contribution) Ma, J.; Xie, X.; Meggers, E. Catalytic asymmetric synthesis of fluoroalkyl‐containing compounds by three‐component photoredox chemistry. Chem. Eur. J. 2018, 24, 259. Ma, J.; Rosales, R. A.; Huang, X., Harms, K.; Riedel, R.; Wiest, O.; Meggers, E. Visible-light-activated asymmetric beta-C–H functionalization of acceptor-substituted ketones with 1,2-dicarbonyl compounds. J. Am. Chem. Soc. 2017, 139, 17245. Ma, J.; Harms, K.; Meggers, E. Enantioselective rhodium/ruthenium photoredox catalysis en route to chiral 1,2-aminoalcohols. Chem. Commun. 2016, 52, 10183. Ma, J.; Shen, X.; Harms, K.; Meggers, E. Expanding the family of bis-cyclometalated chiral-at-metal rhodium(iii) catalysts with a benzothiazole derivative. Dalton Trans. 2016, 45, 8320. Ma, J.; Ding, X.; Hu, Y.; Huang, Y.; Gong, L.; Meggers, E. Metal-templated chiral Brønsted base organocatalysis. Nat. Commun. 2014, 5, 4531. Chen, L.-A.; Xu, W.; Huang, B.; Ma, J.; Wang, L.; Xi, J.; Harms, K.; Gong, L.; Meggers, E. Asymmetric catalysis with an inert chiral-at-metal iridium complex. J. Am. Chem. Soc. 2013, 135, 10598. Chen, L.-A.; Ma, J.; Celik, M. A.; Yu, H.-L.; Cao, Z.; Frenking, G.; Gong, L.; Meggers, E. Active versus passive substituent participation in the auxiliary-mediated asymmetric synthesis of an octahedral metal complex. Chem. Asian J. 2012, 7, 2523.

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