梁沛 - 中国农业大学 - 植物保护学院

个人简介

工作经历 2017/1-至今中国农业大学，植物保护学院昆虫学系，研究员 2003/7-2016/12 中国农业大学，农学与生物技术学院昆虫学系，副教授 2001/7-2003/9 中国农业大学，农学与生物技术学院昆虫学系，讲师教育经历 1998/9-2001/6 中国农业大学昆虫学系，农业昆虫与害虫防治专业，博士 1995/9-1998/6 陕西师范大学生命科学学院，动物学专业，硕士 1991/9-1995/6 石河子农学院农学系，植物保护专业，本科学术兼职中国昆虫学会药剂毒理专业委员会副主任北京昆虫学会理事科研项目近年主持的主要科研项目科技部基础资源调查专项课题，麦类作物害虫抗药性基因和敏感基因资源调查，2018.1-2023.12 国家自然科学基金面上项目，氯虫苯甲酰胺调控小菜蛾性信息素生物合成的分子机制，2018/1-2021/12 国家自然科学基金面上项目，小菜蛾对氯虫苯甲酰胺抗性相关lncRNA的功能分析，2016/1-2019/12 国家自然科学基金面上项目，氯虫苯甲酰胺抗性小菜蛾鱼尼丁受体特性及抗性相关miRNA功能研究，2014/1-2017/12 国家自然科学基金面上项目，小菜蛾对呋喃虫酰肼抗性相关microRNA的鉴定及功能，2012/1-2015/12 国家863课题，重要病虫抗药性早期快速分子诊断技术研究，2012/1-2015/12 国家自然科学基金面上项目，呋喃虫酰肼抗性小菜蛾EcR/USP基因表达及功能，2010/1-2012/12 国家自然科学基金面上项目，小菜蛾对呋喃虫酰肼抗性的生化机制及EcR基因克隆，2007/1-2009/12 国家自然科学基金面上项目，阿维菌素抗性小菜蛾GABA受体基因的表达与调控，2004/1-2006/12

研究领域

昆虫毒理学主要研究重要农业害虫对杀虫药剂抗性的分子机制及抗性治理。

近期论文

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The gut symbiont Sphingomonas mediates imidacloprid resistance in the important agricultural insect pest Aphis gossypii Glover A novel V263I mutation in the glutamate-gated chloride channel of Plutella xylostella (L.) confers a high level of resistance to abamectin Establishment of Toxicity and Susceptibility Baseline of Broflanilide for Aphis gossypii Glove Status of the Resistance of Aphis gossypii Glover, 1877 (Hemiptera: Aphididae) to Afidopyropen Originating from Microbial Secondary Metabolites in China CRISPR /Cas9‐mediated D472N substitution in the Rdl1 of Plutella xylostella confers low resistance to abamectin Overexpression of PxαE14 Contributing to Detoxification of Multiple Insecticides in Plutella xylostella (L.) miR-34-5p, a novel molecular target against lepidopteran pests Influence of seasonal migration on evolution of insecticide resistance in Plutella xylostella Regulation of GSTu1-mediated insecticide resistance in Plutella xylostella by miRNA and lncRNA Development of resistance to chlorantraniliprole represses sex pheromone responses in male Plutella xylostella (L.) Resistance and fitness costs in diamondback moths after selection using broflanilide, a novel meta‐diamide insecticide Identification of ABCG transporter genes associated with chlorantraniliprole resistance in Plutella xylostella (L.) Sublethal and lethal effects of the imidacloprid on the metabolic characteristics based on high-throughput non-targeted metabolomics in Aphis gossypii Glover Functional analysis of a carboxylesterase gene involved in beta‐cypermethrin and phoxim resistance in Plutella xylostella (L.) Amino acids serve as an important energy source for adult flukes of Clonorchis sinensis MiR-189,942 regulates fufenozide susceptibility by modulating ecdysone receptor isoform B in Plutella xylostella (L.) Overexpression of multiple cytochrome P450 genes associated with sulfoxaflor resistance in Aphis gossypii Glover Identification and RNAi-based function analysis of chitinase family genes in diamondback moth, Plutella xylostella Transcription factor FTZ‐F1 and cis‐acting elements mediate expression of CYP6BG1 conferring resistance to chlorantraniliprole in Plutella xylostella Effects of high temperature on insecticide tolerance in whitefly Bemisia tabaci (Gennadius) Q biotype Overexpression of cytochrome P450 CYP6BG1 may contribute to chlorantraniliprole resistance in Plutella xylostella (L.): CYP6BG1 may contribute to chlorantraniliprole resistance in P. xylostella Characterization of UDP-glucuronosyltransferase genes and their possible roles in multi-insecticide resistance in Plutella xylostella (L.): UGT genes involved in multi-insecticide resistance in P. xylostella Silence of inositol 1,4,5-trisphosphate receptor expression decreases cyantraniliprole susceptibility in Bemisia tabaci A P-glycoprotein gene serves as a component of the protective mechanisms against 2-tridecanone and abamectin in Helicoverpa armigera Genome-wide identification of lncRNAs associated with chlorantraniliprole resistance in diamondback moth Plutella xylostella (L.) Global identification of microRNAs associated with chlorantraniliprole resistance in diamondback moth Plutella xylostella (L.) Overexpression of UDP- glycosyltransferase gene UGT2B17 is involved in chlorantraniliprole resistance in Plutella xylostella (L.) cDNA cloning and characterization of the carboxylesterase pxCCE016b from the diamondback moth, Plutella xylostella L. Survey of organophosphate resistance and an A1a216Ser substitution of acetylcholinesterase-1 gene associated with chlorpyrifos resistance in Apolygus lucorum (Meyer-Dur) collected from the transgenic Bt cotton fields in China Induction of Cytochrome P450 Activity by the Interaction of Chlorantraniliprole and Sinigrin in the Spodoptera exigua (Lepidoptera: Noctuidae) MiRNAs regulated overexpression of ryanodine receptor is involved in chlorantraniliprole resistance in Plutella xylostella (L.) Novel mutations and mutation combinations of ryanodine receptor in a chlorantraniliprole resistant population of Plutella xylostella (L.) Biochemical Mechanism of Chlorantraniliprole Resistance in the Diamondback Moth, Plutella xylostella Linnaeus Functional analysis of a point mutation in the ryanodine receptor of Plutella xylostella (L.) associated with resistance to chlorantraniliprole Functional analysis of a point mutation in the ryanodine receptor ofPlutella xylostella(L.) associated with resistance to chlorantraniliprole Fluorescent Probes for Insect Ryanodine Receptors: Candidate Anthranilic Diamides Duplication of acetylcholinesterase gene in diamondback moth strains with different sensitivities to acephate Enantioseparation of Methyl 2-Hydroxypropionate with Two Peracylated β-Cyclodextrin Derivatives as CGC Chiral Stationary Phases Expression Profiling in Bemisia tabaci under Insecticide Treatment: Indicating the Necessity for Custom Reference Gene Selection Fluorescent Probes for Insect Ryanodine Receptors: Candidate Anthranilic Diamides Identification and Developmental Profiling of microRNAs in Diamondback Moth, Plutellaxylostella (L.) Sublethal and transgenerational effects of chlorantraniliprole on biological traits of the diamondback moth, Plutella xylostella L Cloning, characterisation and expression profiling of the cDNA encoding the ryanodine receptor in diamondback moth, Plutella xylostella (L.) (Lepidoptera: Plutellidae) Cloning, ligand-binding, and temporal expression of ecdysteroid receptors in the diamondback moth, Plutella xylostella Omethoate-Induced Changes of (+)-δ-Cadinene Synthase Activity and Gossypol Content in Cotton Seedlings Synthesis of Substituted Phenylpropyl Aldehyde Thiosemicarbazone Compounds and Their Bioactivity on Tyrosinase of Cotton Bollworm Short-term and transgenerational effects of the neonicotinoid nitenpyram on susceptibility to insecticides in two whitefly species Quantification of γ‐aminobutyric acid in the heads of houseflies (Musca domestica) and diamondback moths (Plutella xylostella (L.)), using capillary electrophoresis with laser‐induced fluorescence detection Frequencies of the M918I mutation in the sodium channel of the diamondback moth in China, Thailand and Japan and its association with pyrethroid resistance Cross-resistance patterns and fitness in fufenozide-resistant diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae) Effects of insecticides on fluidity of mitochondrial membrane by fluorescence probe DPH in Chilo suppressalis The stability and biochemical basis of fufenozide resistance in a laboratory-selected strain of Plutella xylostella