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个人简介

刘佳利 博士,副教授。现于中国农业大学生物学院动物生理系和农业生物技术国家重点实验室从事科研教学工作。 学习与工作经历 2017.11-2018.2,美国密歇根州立大学 生殖与发育生物学实验室,合作研究 2014.10-2017.8, 美国密歇根州立大学 生殖与发育生物学实验室,访问学者 2009.1-2010.1:意大利比萨大学 细胞与发育生物学实验室,访问学者 2008.1-至今 中国农业大学,副教授 2005.7-2007.12:中国农业大学, 讲师 2000.9-2005.7:中国农业大学,硕士,博士 1995.8-2000.7:辽宁省沈阳生物技术研究所 研究实习员 1991.9-1995.7:北京农业大学,本科 主讲课程 《动物生理学》(本科生) 《动物生理学实验》(本科生) 《生理学大实验及实验设计》(本科生) 《现代生命科学研究技术-免疫组织化学》(研究生)

研究领域

动物生殖与发育的调控机理

近期论文

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Ding D, Liu J, Midic U, Wu Y, Dong K, Melnick A, Latham KE, Chen C. TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice. Nat Commun. 2018, 9;9(1):127. doi: 10.1038/s41467-017-02622-w. Ding D#, Liu J#, Dong K#, Midic U, Hess RA, Xie H, Demireva EY, Chen C*. PNLDC1 is essential for piRNA 3' end trimming and transposon silencing during spermatogenesis in mice. Nat Commun. 2017, 10;8(1):819. doi: 10.1038/s41467-017-00854-4. (“#”, Co-first authors). Zhao J, Zhao J, Xu G, Wang Z, Gao J, Cui S, Liu J*. Deletion of Spata2 by CRISPR/Cas9n causes increased inhibin alpha expression and attenuated fertility in male mice. Biol Reprod. 2017, 1;97(3):497-513. doi: 0.1093/biolre/iox093. Li X, Wang S, Zhang L, Zhang L, Liu J, Luo H, Gou K, Cui S*. Amitriptyline plays important roles in modifying the ovarian morphology and improving its functions in rats with estradiol valerate-induced polycystic ovary. Arch Pharm Res. 2017, 8. doi: 10.1007/s12272-015-0573-z. [Epub ahead of print]. He J, Wei C, Li Y, Liu Y, Wang Y, Pan J, Liu J, Wu Y*, Cui S*. Zearalenone and alpha-zearalenol inhibit the synthesis and secretion of pig follicle stimulating hormone via the non-classical estrogen membrane receptor GPR30. Mol Cell Endocrinol. 2017 Aug 19. pii: S0303-7207(17)30432-X. doi: 10.1016/j.mce. 2017.08.010. [Epub ahead of print]. Wang S, Liu J, Li X, Ji X, Zhang J, Wang Y, Cui S*. MiR-125b Regulates Primordial Follicle Assembly by Targeting Activin Receptor Type 2a in Neonatal Mouse Ovary. Biol Reprod. 2016, 94(4):83 (Co-first author). Liu S, Liu Y, Ma Q, Cui S, Liu J*. Expression and localization of cysteine sulfinate decarboxylase in major salivary glands of male mice. Arch Oral Biol. 2015, 60(4):615-21. Liu Y, Li Y, Zhang D, Liu J, Gou K, Cui S*. Mitogen-Activated Protein Kinase 8 (MAP3K8) Mediates the Signaling Pathway of Estradiol Stimulating Progesterone Production Through G Protein-Coupled Receptor 30 (GPR30) in Mouse Corpus Luteum. Mol Endocrinol. 2015, 29(5):703-15. Ma Q, Zhao J, Cao W, Liu J, Cui S*. Estradiol decreases taurine level by reducing cysteine sulfinic acid decarboxylase via the estrogen receptor-α in female mice liver. Am J Physiol Gastrointest Liver Physiol. 2015, 308(4):G277-86. Chen J, Fu R, Cui Y, Pan J, Li Y, Zhang X, Evans SM, Cui S, Liu J*. LIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice. Mol Endocrinol. 2014, 28(8): 1276-90. Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, Zhang X, Evans SM, Cui Y, Cui S*. LIM homeodomain transcription factor Isl1 directs normal pyloric development via targeting Gata3. BMC Biology. 2014, 12:25. Cao W, Chen W, Liang X, Zhou J, Wei C, Cui S, Liu J*. All-trans-retinoic Acid ameliorates the inflammation by inducing transforming growth factor Beta 1 and interleukin 10 in mouse epididymitis. Am J Reprod Immunol. 2014, 71(4):312-21. Zhang X, Li J, Liu J, Luo H, Gou K, Cui S*. Prostaglandin F2α upregulates Slit/Robo expression in mouse corpus luteum during luteolysis. J Endocrinol. 2013, 218(3):299-310. Chen J, Fu R, Cui Y, Li Y, Pan J, Liu J, Luo H, Yin J, Li D, Cui S*. LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice. J Biol Chem. 2013, 288(17):12395-12405. Zhang N, Lin J, Chen J, Liu X, Liu J, Luo H, Li Y, and Cui S*. MicroRNA 375 mediates the signaling pathway of corticotropin-releasing factor (CRF) regulating pro-opiomelanocortin (POMC) expression by targeting mitogen-activated protein. J Biol Chem. 2013, 288(15):10361-10373. Zhang J, Ji X, Zhou D, Li Y, Lin J, Luo H, Liu J and Cui S*. miR-143 is critical for the formation of primordial follicles in mice. Front Biosci (Landmark) 2013; 18(1): 588-597. Liang X, Zhou D, Wei C, Luo H, Liu J, Fu R , Cui S*. MicroRNA-34c enhances murine male germ cell apoptosis through targeting ATF1. PLoS One. 2012, 7(3):e33861. Sun D, Cui T, Luo H, Li R, Cui S, Liu J*. Cell-specific distributions of estrogen receptor alpha (ERα) and androgen receptor (AR) in anterior pituitary glands from adult cockerels as revealed by immunohistochemistry. Cell Tissue Res. 2012;348(3):551-558. Fu R#, Liu J#, Fan J, Li R, Yin J, Cui S*. Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line. J Cell Physiol 2012; 227(1):98-107. (Co-first author) Wu Y, Luo H, Liu J, Kang D, McNeilly AS, Cui S*. LIM homeodomain transcription factor Isl-1 enhances follicle stimulating hormone-beta and luteinizing hormone-beta gene expression and mediates the activation of leptin on gonadotropin synthesis. Endocrinology. 2010; 151(10): 4787-4800. Chen D, Wang G, Luo H, Liu J, Cui S*. Isl-1 down-regulates DRG cell proliferation during chicken embryo development. Neuro Endocrinol Lett. 2010; 31(1): 67-72. Wang G, Chen D, Luo H, Liu J, Ji X, Fan J, Cui S*. Low-dose ethanol suppresses 17beta-estradiol activity in GH4C1 pituitary tumor cells. Cell Biol Toxicol. 2010; 26(3): 265-277. Wu YJ, Chen DW, Liu JL, Zhang JH, Luo HS, Cui S*. Estradiol promotes pituitary cell proliferation and gonadotroph differentiation at different doses and with different mechanisms in chick embryo. Steroids. 2009; 74(4-5): 441-448. Luo H, Liu J, Kang D, Cui S*. Ontogeny of estrogen receptor alpha, estrogen receptor beta and androgen receptor, and their co-localization with Islet-1 in the dorsal root ganglia of sheep fetuses during gestation. Histochem Cell Biol. 2008; 129(4): 525-533. Liu S, Luo H, Liu J, McNeilly AS, Cui S*. Specificity protein 1 (Sp1) plays role in regulating LIM homeodomain transcription factor Lhx4 gene expression. Biochem Biophys Res Commun. 2008; 366(1): 36-41. Yang JY, Wang GX, Liu JL, Fan JJ, Cui S*. Toxic effects of zearalenone and its derivatives alpha-zearalenol on male reproductive system in mice. Reprod Toxicol. 2007; 24(3-4): 381-387. Yuan X, He Y, Liu J, Luo H, Zhang J, Cui S*. Expression of androgen receptor and its co-localization with estrogen receptor-alpha in the developing pituitary gland of sheep fetus. Histochem Cell Biol. 2007; 127(4): 423-432. Zhang JH, Liu JL, Wu YJ, Cui S*. LIM homeodomain proteins Islet-1 and Lim-3 expressions in the developing pineal gland of chick embryo by immunohistochemistry. J Pineal Res. 2006; 41(3): 247-254. Liu J, Liu Z, Yi S, Cui S*. Islet-1 expression and its co-localization with luteinising hormone, thyroid stimulating hormone and oestrogen receptor alpha in the developing pituitary gland of sheep fetuses. J Neuroendocrinol, 2005; 17(12): 773-780. Liu J, Chen D, Goldstein RS,Cui S*.Effects of male and female sex steroids on the development of normal and the transient Froriep's dorsal root ganglia of the chick embryo. Dev Brain Res. 2005; 155(1): 14-25. Liu J, Cui S*. Ontogeny of estrogen receptor (ER) alpha and its co-localization with pituitary hormones in the pituitary gland of chick embryos. Cell Tissue Res. 2005; 320(2): 235-242. Liu J#, He Y#, Wang X, Zheng X, Cui S*. Developmental changes of Isl1 and its co-localization with pituitary hormones in the pituitary gland of chick embryo by immunohistochemistry. Cell Tissue Res. 2005; 322(2): 279-287. Tian X, Cui S*, Liu J, Yi S. Expression of estrogen receptors in the efferent ductule of male sheep fetuses during gestation. Histochem Cell Biol. 2004;122(5):473-475. Luo H, Cui S*, Chen D, Liu J, Liu Z.Immunohistochemical detection of islet-1 and neuronal nitric oxide synthase in the dorsal root ganglia (DRG) of sheep fetuses during gestation. J Histochem Cytochem. 2004;52(6):797-803. Cui S*, Liu J, Shao Y, Zhang JC. Parallel changes between the percentage of fetal pituitary cells immunoreactive to oestrogen receptor alpha and the concentration of 17beta-oestradiol in fetal and maternal plasma during gestation in sheep. Reprod Fertil Dev. 2004;16(6):611-616.

学术兼职

中国畜牧兽医学会动物生理生化分会理事

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