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学习经历 2007/09-2011/06:中国农业大学,动物科学、工商管理(双学位),学士 2011/09-2016/06:中国农业大学,动物遗传育种与繁殖专业,博士 其中,2015/01-2016/01:Animal & Avian Sciences,University of Maryland,USA,联培博士 工作经历 2016/07-2018/04:中国农业大学,生物学院,博士后 2018/05-2019/11:中国农业大学,动物科学技术学院,讲师 2019/12-今:中国农业大学,动物科学技术学院,副教授 科研项目 国家自然科学基金面上项目,奶牛乳脂性状关键候选基因及其突变位点功能验证研究,58万元,2021/01-2024/12,主持 国家重点研发计划,奶牛、羊高产优质高效形状形成的分子调控网络,200万元,2021/12-2026/11,子课题主持 国家重点研发计划,主要农业反刍动物优异种质资源精准鉴定,45万元,2021/12-2026/11,子课题主持 国家自然科学基金青年科学基金项目,奶牛乳脂性状关键基因及其ceRNA调控机制研究,20万元,2019/01-2020/12,主持 国家自然科学基金面上项目,奶牛乳成分性状形成的调控通路研究及关键基因鉴定,59万元,2019/01-2022/12,参与 中国农业大学基本科研业务费专项资金项目,奶牛不同泌乳阶段ceRNA调控网络分析研究,8万元,2020/01-2020/09,主持 横向项目,奶牛健康及抗病遗传育种技术服务,5万元,2018/06-2019/06,主持 中国博士后科学基金面上项目,中国荷斯坦牛不同泌乳阶段肝脏ceRNA调控网络研究,5万元,2017/06-2018/06,主持

研究领域

奶牛分子育种、功能基因组学、表观遗传学

近期论文

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Du A, Zhao F, Liu Y, Xu L, Chen K, Sun D, Han B*: Genetic polymorphisms of PKLR gene and their associations with milk production traits in Chinese Holstein cows. Front Genet 2022, 13:1002706. Ye W, Xu L, Li Y, Liu L, Ma Z, Sun D, Han B*: Single Nucleotide Polymorphisms of ALDH18A1 and MAT2A Genes and Their Genetic Associations with Milk Production Traits of Chinese Holstein Cows. Genes (Basel) 2022, 13(8). Fu Y, Jia R, Xu L, Su D, Li Y, Liu L, Ma Z, Sun D, Han B*: Fatty acid desaturase 2 affects the milk-production traits in Chinese Holsteins. Anim Genet 2022, 53(3):422-426. Jia R, Fu Y, Xu L, Li H, Li Y, Liu L, Ma Z, Sun D, Han B*: Associations between polymorphisms of SLC22A7, NGFR, ARNTL and PPP2R2B genes and Milk production traits in Chinese Holstein. BMC Genom Data 2021, 22(1):47. Shi L, Liu L, Lv X, Ma Z, Li C, Li Y, Zhao F, Sun D, Han B*: Identification of genetic effects and potential causal polymorphisms of CPM gene impacting milk fatty acid traits in Chinese Holstein. Anim Genet 2020, 51(4):491-501. Han B, Yuan Y, Shi L, Li Y, Liu L, Sun D: Identification of single nucleotide polymorphisms of PIK3R1 and DUSP1 genes and their genetic associations with milk production traits in dairy cows. J Anim Sci Biotechnol 2019, 10:81. Shi L, Liu L, Lv X, Ma Z, Yang Y, Li Y, Zhao F, Sun D, Han B*: Polymorphisms and genetic effects of PRLR, MOGAT1, MINPP1 and CHUK genes on milk fatty acid traits in Chinese Holstein. BMC Genet 2019, 20(1):69. Xu L, Shi L, Liu L, Liang R, Li Q, Li J, Han B*, Sun D*: Analysis of Liver Proteome and Identification of Critical Proteins Affecting Milk Fat, Protein, and Lactose Metabolism in Dariy Cattle with iTRAQ. Proteomics 2019, 19(12):e1800387. Shi L#, Han B#, Liu L, Lv X, Ma Z, Li C, Xu L, Li Y, Zhao F, Yang Y et al: Determination of Genetic Effects of LIPK and LIPJ Genes on Milk Fatty Acids in Dairy Cattle. Genes (Basel) 2019, 10(2). Han B, Yuan Y, Liang R, Li Y, Liu L, Sun D: Genetic Effects of LPIN1 Polymorphisms on Milk Production Traits in Dairy Cattle. Genes (Basel) 2019, 10(4). Han B#, Yuan Y#, Li Y, Liu L, Sun D: Single Nucleotide Polymorphisms of NUCB2 and their Genetic Associations with Milk Production Traits in Dairy Cows. Genes (Basel) 2019, 10(6). Han B, Liang W, Liu L, Li Y, Sun D: Genetic association of the ACACB gene with milk yield and composition traits in dairy cattle. Anim Genet 2018, 49(3):169-177. Han B#, Liang W#, Liu L, Li Y, Sun D: Determination of genetic effects of ATF3 and CDKN1A genes on milk yield and compositions in Chinese Holstein population. BMC Genet 2017, 18(1):47. Liang R#, Han B#, Li Q, Yuan Y, Li J, Sun D: Using RNA sequencing to identify putative competing endogenous RNAs (ceRNAs) potentially regulating fat metabolism in bovine liver. Sci Rep 2017, 7(1):6396. Han B#, He Y#, Zhang L, Ding Y, Lian L, Zhao C, Song J, Yang N: Long intergenic non-coding RNA GALMD3 in chicken Marek's disease. Sci Rep 2017, 7(1):10294. Han B#, Lian L#, Li X, Zhao C, Qu L, Liu C, Song J, Yang N: Chicken gga-miR-103-3p Targets CCNE1 and TFDP2 and Inhibits MDCC-MSB1 Cell Migration. G3 (Bethesda) 2016, 6(5):1277-1285. Han B, Lian L, Li X, Zhao C, Qu L, Liu C, Song J, Yang N: Chicken gga-miR-130a targets HOXA3 and MDFIC and inhibits Marek's disease lymphoma cell proliferation and migration. Mol Biol Rep 2016, 43(7):667-676. Han B, Lian L, Qu L, Zheng J, Yang N: Abundant polymorphisms at the microsatellite locus LEI0258 in indigenous chickens. Poult Sci 2013, 92(12):3113-3119. Lin S, Ke C, Liu L, Gao Y, Xu L, Han B, Zhao Y, Zhang S, Sun D: Genome-wide association studies for immunoglobulin concentrations in colostrum and serum in Chinese Holstein. BMC Genomics 2022, 23(1):41. Li H, Huang J, Zhang J, Gao Y, Han B, Sun D: Identification of Alternative Splicing Events Associated with Paratuberculosis in Dairy Cattle Using Multi-Tissue RNA Sequencing Data. Genes (Basel) 2022, 13(3). Hou Y, Xie Y, Yang S, Han B, Shi L, Bai X, Liang R, Dong T, Zhang S, Zhang Q et al: EEF1D facilitates milk lipid synthesis by regulation of PI3K-Akt signaling in mammals. FASEB J 2021, 35(5):e21455. Zhang J, Han B, Zheng W, Lin S, Li H, Gao Y, Sun D: Genome-Wide DNA Methylation Profile in Jejunum Reveals the Potential Genes Associated With Paratuberculosis in Dairy Cattle. Front Genet 2021, 12:735147. Shi L, Wu X, Yang Y, Ma Z, Lv X, Liu L, Li Y, Zhao F, Han B, Sun D: A post-GWAS confirming the genetic effects and functional polymorphisms of AGPAT3 gene on milk fatty acids in dairy cattle. J Anim Sci Biotechnol 2021, 12(1):24. Cao M, Shi L, Peng P, Han B, Liu L, Lv X, Ma Z, Zhang S, Sun D: Determination of genetic effects and functional SNPs of bovine HTR1B gene on milk fatty acid traits. BMC Genomics 2021, 22(1):575. Lin S, Wan Z, Zhang J, Xu L, Han B, Sun D: Genome-Wide Association Studies for the Concentration of Albumin in Colostrum and Serum in Chinese Holstein. Animals (Basel) 2020, 10(12). Ilie DE, Gao Y, Nicolae I, Sun D, Li J, Han B, Gavojdian D: Evaluation of single nucleotide polymorphisms identified through the use of SNP assay in Romanian and Chinese Holstein and Simmental cattle breeds. Acta Biochim Pol 2020, 67(3):341-346. Shi L, Lv X, Liu L, Yang Y, Ma Z, Han B, Sun D: A post-GWAS confirming effects of PRKG1 gene on milk fatty acids in a Chinese Holstein dairy population. BMC Genet 2019, 20(1):53. Shi L, Liu L, Ma Z, Lv X, Li C, Xu L, Han B, Li Y, Zhao F, Yang Y et al: Identification of genetic associations of ECHS1 gene with milk fatty acid traits in dairy cattle. Anim Genet 2019, 50(5):430-438. Lin S, Zhang H, Hou Y, Liu L, Li W, Jiang J, Han B, Zhang S, Sun D: SNV discovery and functional candidate gene identification for milk composition based on whole genome resequencing of Holstein bulls with extremely high and low breeding values. PLoS One 2019, 14(8):e0220629. He Y#, Han B#, Ding Y, Zhang H, Chang S, Zhang L, Zhao C, Yang N, Song J: Linc-GALMD1 Regulates Viral Gene Expression in the Chicken. Front Genet 2019, 10:1122. Zhao C, Li X, Han B, Qu L, Liu C, Song J, Lian L, Yang N: Gga-miR-130b-3p inhibits MSB1 cell proliferation, migration, invasion, and its downregulation in MD tumor is attributed to hypermethylation. Oncotarget 2018, 9(36):24187-24198. Gao Y, Jiang J, Yang S, Cao J, Han B, Wang Y, Zhang Y, Yu Y, Zhang S, Zhang Q et al: Genome-wide association study of Mycobacterium avium subspecies Paratuberculosis infection in Chinese Holstein. BMC Genomics 2018, 19(1):972. Zhao C, Li X, Han B, You Z, Qu L, Liu C, Song J, Lian L, Yang N: Gga-miR-219b targeting BCL11B suppresses proliferation, migration and invasion of Marek's disease tumor cell MSB1. Sci Rep 2017, 7(1):4247. He Y, Ding Y, Zhan F, Zhang H, Han B, Hu G, Zhao K, Yang N, Yu Y, Mao L et al: The conservation and signatures of lincRNAs in Marek's disease of chicken. Sci Rep 2015, 5:15184.

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