余春红 - 北京航空航天大学 - 医学科学与工程学院 / 医工交叉创新研究院

个人简介

教育背景 2015-9至2016-9, 伦敦大学学院, 结构分子生物学, 联合培养博士生, 导师: Emmanuel Boucrot 2013-9至2019-6, 北京航空航天大学, 生物医学工程, 博士, 导师: 荣龙、易宗春 2012-9至2013-7, 北京航空航天大学, 生物医学工程, 硕转博, 导师: 易宗春 2008-9至2012-7, 北京航空航天大学, 生物工程, 学士工作经历 2019-7至今北京航空航天大学, 医学科学与工程学院, 讲师代表性科研项目顺义区“北京市科技成果转化统筹协调与服务平台”建设专项：新型人造血（氧载体）的开发，2021-10至2023-09、40万元、在研、参与北京航空航天大学医工卓越创新计划项目，新冠肺炎危重症患者抢救用人工氧载体的可行性研究，2020-10至2021-09、7万元、在研、主持国家自然科学基金面上项目81573192：GATA因子转换失调在苯代谢物抑制红系分化过程中的作用，2015/01-2019/12、55万、结题、参与北航博士生卓越学术基金：GATA因子转换在苯代谢物影响红系分化中的干预作用，2018/05-2019/05、4万、结题、主持

研究领域

从细胞、分子和多组学层面研究活性氧、基因转录调控、DNA甲基化和组蛋白修饰等在环境污染物苯的血液毒性中作用机制肝细胞的上皮间质转化机制研究静止期细胞标志物及相关信号通路研究蚯蚓血红蛋白人工氧载体临床前研究

近期论文

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Yu Chun-Hong; Yang Shui-Qing; Zhang Yu-Jing; Rong Long; Yi Zong-Chun*; The role of GATA switch in benzene metabolite hydroquinone inhibiting erythroid differentiation in K562 cells, Archives of Toxicology, 2023, 97(8):2169-2181. Yu Chun-Hong; Yang Shui-Qing; Li Lei; Xin Yu; Zhang Fang; Liu Xiao-Fan; Yi Zong-Chun*; Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells, BMC Pharmacol Toxicol. 2022, 23(1): 20. Li Lei; Xun Chen; Yu Chun-Hong*. Role of microRNA-regulated cancer stem cells in recurrent hepatocellular carcinoma. World journal of hepatology, 2022,14(12):1985-1996. Yu Chun Hong; Li Yang; Zhao Xiao; Yang Shui Qing; Li Lei; Cui Ning Xuan; Rong Long; Yi Zong Chun*; Benzene metabolite 1,2,4-benzenetriol changes DNA methylation and histone acetylation of erythroid-specific genes in K562 cells, Archives of Toxicology, 2019, 93(1): 137-147. Yu Chun Hong; Jiang Liang; Wang Ying; Cui Ning Xuan; Zhao Xiao; Yi Zong Chun*; Inhibition of erythroid differentiation of human leukemia K562 cells by N-acetylcysteine and ascorbic acid through downregulation of ROS, Biomedical and Environmental Sciences, 2018, 31(3): 247-251. Yu Chun Hong; Suriguga; Gong Meng; Liu Wen Juan; Cui Ning Xuan; Wang Ying; Du Xin*; Yi Zong Chun*; High glucose induced endothelial to mesenchymal transition in human umbilical vein endothelial cell, Experimental and Molecular Pathology, 2017, 102(3): 377-383. Yu Chun Hong; Cui Ning Xuan; Wang Yan; Wang Ying; Liu Wen Juan; Gong Meng; Zhao Xiao; Rong Long; Yi Zong Chun*; Changes in DNA methylation of erythroid-specific genes in K562 cells exposed to catechol in long term, Toxicology in Vitro, 2017, 43: 21-28. Yu Chun Hong; Wang Hong; Wang Ying; Cui Ning Xuan; Zhao Xiao; Rong Long; Yi Zong Chun*; Protease sensitivity and redistribution of CD71 and glycophorin A on K562 cells, Cellular and Molecular Biology, 2017, 63(9): 40. 余春红; 易宗春*; 吞蛋白A2在非网格蛋白内吞中的作用研究进展, 生物化学与生物物理进展, 2017,44 (01): 44-48. Yu Chun Hong; Suriguga; Li Yang; Li Yi Ran; Tang Ke Ya; Jiang Liang; Yi Zong Chun*; The role of ROS in hydroquinone-induced inhibition of K562 cell erythroid differentiation, Biomedical and Environmental Sciences, 2014, 27(3): 212-214. 余春红; 苏日咕嘎; 李扬; 李怡然; 唐恪雅; 姜良; 易宗春*; 5-氮杂-2’-脱氧胞苷对苯代谢物抑制K562细胞转铁蛋白受体表达的干预作用, 毒理学杂志, 2014, (04): 269-273. Tang Ke Ya; Yu Chun Hong; Jiang Liang; Gong Meng; Liu Wen Juan; Wang Ying; Cui Ning Xuan; Song Wei; Sun Yan; Yi Zong Chun, Long-term exposure of K562 cells to benzene metabolites inhibited erythroid differentiation and elevated methylation in erythroid specific genes, Toxicology Research, 2016, 5(5): 1284-1297. Wang Yan; Zhang Guang Yao; Han Qing Ling; Wang Jie; Suriguga; Li Yang; Yu Chun Hong; Li Yi Ran; Yi Zong Chun, Phenolic Metabolites of Benzene Induced Caspase-Dependent Cytotoxicities to K562 Cells Accompanied with Decrease in Cell Surface Sialic Acids, Environmental Toxicology, 2014, 29(12): 1437-1451. Suriguga; Li Xiao Fei; Li Yang; Yu Chun Hong; Li Yi Ran; Yi Zong Chun, The role of catechol-O-methyltransferase in catechol-enhanced erythroid differentiation of K562 cells, Toxicology and Applied Pharmacology, 2013, 273(3): 635-643. Li Yang; Wu Xiao Rong; Li Xiao Fei; Suriguga; Yu Chun Hong; Li Yi Ran; Yi Zong Chun, Changes in DNA methylation of erythroid-specific genes in K562 cells exposed to phenol and hydroquinone, Toxicology, 2013, 312: 108-114.