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个人简介

since 04 / 2013 Dean of Research, Faculty of Chemistry, Georg-August-University Göttingen 2013 Offer for a Chair and Full Professor at the RWTH Aachen (declined) 04 / 2011 – 03 / 2013 Dean of the Faculty of Chemistry, Georg-August-University Göttingen since 05 / 2007 Chair and Full Professor (W3) at the Georg-August-University Göttingen 06 / 2003 – 04 / 2007 Emmy Noether-Fellow (DFG): Independent research at the LMU München (Mentor: Prof. Dr. P. Knochel) 07 / 2001 – 05 / 2003 Postdoctoral Studies with Prof. Dr. R. G. Bergman, UC Berkeley 06 / 1998 – 06 / 2001 Ph.D. thesis (Mentor: Prof. Dr. A. Fuerstner), Max-Planck-Institut für Kohlenforschung in Muelheim/Ruhr and the University Dortmund (summa cum laude) 08 – 12 / 1999 Research stay at the Université de Rennes, France (Prof. Dr. P. H. Dixneuf) 08 / 1997 – 03 / 1998 Diploma thesis (MSc) (Prof. Dr. J. Mattay) 10 / 1993 – 03 / 1998 Studies of Chemistry at the Christian-Albrechts-Universitaet zu Kiel

研究领域

Organic catalysis: development of new/transition-metal-catalysed reactions aiming at the economical and sustainable synthesis of complex organic molecules.

Our research group is interested in the development of environmentally benign and economically sound processes of importance to organic synthesis. This combines techniques of organic synthesis and organometallic chemistry for the development of more efficient catalytic transformations. Thus far, our program is focused on four main research areas: (A) catalytic functionalizations of unactivated C–H bonds. This work includes the use of inter alias ruthenium, titanium, zirconium, palladium, nickel, and copper catalysts on a day to day basis; (B) development of air-stable secondary phosphine oxides as preligands for catalytic cross-couplings; (C) hydroaminations of alkynes, allenes, and alkenes; and (D) efficient syntheses of biologically relevant compounds.

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

W. Ma, L. Ackermann, "Cobalt(II)-Catalyzed Oxidative C−H Alkenylations: Regio- and Site-Selective Access to Isoindolin-1-one" ACS Catal. 2015, 5, in press. Abstract> M. Moselage, N. Sauermann, S. C. Richter, L. Ackermann, Angew. Chem. Int. Ed. 2015, 54, in press. S. Warratz,' C. Kornhaaß,' A. Cajaraville, B. Niepötter, D. Stalke, L. Ackermann "Ruthenium(II)-Catalyzed C–H Activation/Alkyne Annulation with O2 as the Sole Oxidant by Weak-Coordination" Angew. Chem. Int. Ed. 2015, 54, in press. ' Both authors contributed equally. Abstract> J. Li, L. Ackermann, "Cobalt-Catalyzed C–H Arylations with Weakly-Coordinating Amides and Tetrazoles: Expedient Route to Angiotensin-II-Receptor Blockers" Chem. Eur. J. 2015, 20, 5718-5722. Abstract> C. Tirler, L. Ackermann, "Ruthenium(II)-Catalyzed Cross-Dehydrogenative C−H Alkenylations by Triazole Assistance" Tetrahedron (Symposia in print) 2015, in press. Abstract> W. Liu, D. Zell, M. John, L. Ackermann, "Manganese-Catalyzed Synthesis of cis-β-Amino Acid Esters through Organometallic C–H Activation of Ketimines" Angew. Chem. Int. Ed. 2015, 54, 4092-4096. Abstract> L. Ackermann, "Robust Ruthenium(II)-Catalyzed C–H Arylations: Carboxylate Assistance for the Efficient Synthesis of Angiotensin-II-Receptor Blockers" Org. Process Res. Dev. 2015, 18, 260-269. Abstract> J. Li, L. Ackermann, "Cobalt-Catalyzed C–H Cyanation of Arenes and Heteroarenes" Angew. Chem. Int. Ed. 2015, 54, 3635-3638. Abstract> J. Hubrich, T. Himmler, L. Rodefeld, L. Ackermann, "Ruthenium(II)-Catalyzed C‒H Arylation of Anilides with Boronic Acids, Borinic Acids and Potassium Trifluoroborates" Adv. Synth. Catal. 2015, 357, 474-480. Abstract> K. Raghuvanshi, K. Rauch, L. Ackermann, "Ruthenium(II)-Catalyzed C–H Acyloxylation of Phenols with Removable Auxiliary" Chem. Eur. J. 2015, 20, 1790–1794. Abstract> F. Yang, L. Ackermann, "Dehydrative C–H/N–OH Functionalizations in H2O by Ruthenium(II)-Catalysis: Subtle Effect of Carboxylate Ligands and Mechanistic Insight" J. Org. Chem. 2014, 79, 12070-12082. Abstract> W. Ma, R. Mei, G. Tenti, L. Ackermann, "Ruthenium(II)-Catalyzed Oxidative C–H Alkenylations of Sulfonic Acids, Sulfonyl Chlorides and Sulfonamides" Chem. Eur. J. 2014, 20, 15248-15251. Abstract> F. Yang, K. Rauch, K. Kettelhoit, L. Ackermann, "Aldehyde-Assisted Ruthenium(II)-Catalyzed C–H Oxygenations" Angew. Chem. Int. Ed. 2014, 53, 11285-11288. Abstract> (selected as hot paper) Y. Zhu, M. Bauer, J. Ploog, L. Ackermann, "Late-Stage Diversification of Peptides by Metal-free C–H Arylation" Chem. Eur. J. 2014, 20, 13099-13102. Abstract> S. De Sarkar, L. Ackermann, "Ruthenium(II)-Catalyzed C–H Activation with Isocyanates: Versatile Route to Phthalimides" Chem. Eur. J. 2014, 20, 13932-13936. Abstract> L. Ackermann, "Cobalt-Catalyzed C–H Arylations, Benzylations and Alkylations with Organic Electrophiles and Beyond" J. Org. Chem. 2014, 79, 8948-8954. Abstract> H. H. Al Mamari, E. Diers, L. Ackermann, "Triazole-Assisted Ruthenium-Catalyzed C-H Arylation of Aromatic Amides" Chem. Eur. J. 2014, 20, 9739-9743. Abstract> S. De Sarkar, W. Liu, S. I. Kozhushkov, L. Ackermann, "Weakly-Coordinating Directing Groups for Ruthenium(II)-Catalyzed C–H Activation" Adv. Synth. Catal. 2014, 356, 1461-1479. Abstract> W. Ma, L. Ackermann, "Silver-Mediated Alkyne Annulations by C−H/P−H Functionalizations: Step-Economical Access to Benzophospholes" Synthesis 2014, 2297-2304. Abstract> S. Nakanowatari, L. Ackermann, "Ruthenium(II)-Catalyzed Synthesis of Isochromenes by C−H Activation with Weakly-Coordinating Aliphatic Hydroxyl Groups" Chem. Eur. J. 2014, 20, 5409–5413. Abstract> M. Schinkel, L. Wang, K. Bielefeld, L. Ackermann, "Ruthenium(II)-Catalyzed C(sp3)–H α-Alkylation of Pyrrolidines" Org. Lett. 2014, 16, 1876–1879.

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