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个人简介

Yaroslav Khimyak has moved to a Chair in solid-state NMR spectroscopy in the School of Pharmacy in UEA in September 2011. Until then he was a Senior Lecturer at the Department of Chemistry in the University of Liverpool where he was appointed as a Lecturer in 2002. Yaroslav graduated from Ivan Franko Lviv State University in the Ukraine with an M.Sc. in Chemistry (1994), obtained an M. Phil. (1997) and a Ph. D. (2000) from the University of Cambridge and held a position of Oppenheimer Research Fellow at the Department of Chemistry in the University of Cambridge (1999 – 2002).

研究领域

The research in Yaroslav’s group focuses on understanding structure and dynamics of materials with limited long range ordering using solid-state NMR and demonstrated the importance of characterisation of dynamics on different time scales for ratioanalising the properties of such complex solids. The materials of interest include pharmaceutical solids (polymer/drug composites, amorphous pharmaceuticals) and porous materials (polymers, hybrid silicas, MOFs). Our interest in the application of modern solid-state NMR methodology to elucidate the structure of “soft” solids has attracted industrial support to study amorphous polymer-based materials used for the controlled drug release and glasses.

近期论文

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Takieddin, K., Khimyak, Y., Fabian, L.(2016)Prediction of Hydrate and Solvate Formation Using Statistical Modelsin Crystal Growth & Design16.pp. 70-81 Full Text UEA Repository(Article) Braun, D., Nartowski, K., Khimyak, Y., Morris, K., Byrn, S., Griesser, U.(2016)Structural Properties, Order-Disorder Phenomena and Phase Stability of Orotic Acid Crystal Formsin Molecular Pharmaceutics13.pp. 1012-1029 Full Text UEA Repository(Article) Piana, F., Case, D. H., Campos E Menezes Jorge Ramalhete, S., Pileio, G., Facciotti, M., Day, G. M., Khimyak, Y., Angulo, J., Brown, R. C. D., Gale, P. A.(2016)Substituent interference on supramolecular assembly in urea gelators: synthesis, structure prediction and NMRin Soft Matter12.pp. 4034-4043 Full Text UEA Repository(Article) Nartowski, K., Khimyak, Y., Berry, D.(2016)Tuning the spontaneous formation kinetics of caffeine:malonic acid co-crystalsin CrystEngComm18.pp. 2617-2620 Full Text UEA Repository(Article) Nartowski, K., Malhotra, D., Hawarden, L., Sibik, J., Iuga, D., Zeitler, J. A., Fabian, L., Khimyak, Y.(2016)19F NMR Spectroscopy as a Highly Sensitive Method for the Direct Monitoring of Confined Crystallization within Nanoporous Materialsin Angewandte Chemie International Edition128.pp. 9050-9054 Full Text UEA Repository(Article) Rashid, A. M., Batey, S. F. D., Syson, K., Koliwer-Brandl, H., Miah, F., Barclay, J. E., Findlay, K. C., Nartowski, K. P., Khimyak, Y. Z., Kalscheuer, R., Bornemann, S.(2016)Assembly of α-Glucan by GlgE and GlgB in Mycobacteria and Streptomycetesin Biochemistry55.pp. 3270-3284 Full Text UEA Repository(Article) Piana, F., Case, D. H., Ramalhete, S. M., Pileio, G., Facciotti, M., Day, G. M., Khimyak, Y. Z., Angulo Alvarez, J., Brown, R. C. D., Gale, P. A.(2016)Correction: Substituent interference on supramolecular assembly in urea gelators: synthesis, structure prediction and NMRin Soft Matter12.pp. 5489 Full Text UEA Repository(Article) Sarcevica, I., Orola, L., Nartowski, K., Khimyak, Y., Round, A., Fabian, L.(2015)Mechanistic and kinetic insight into spontaneous cocrystallisation of isoniazid and benzoic acidin Molecular Pharmaceutics12.pp. 2981–2992 Full Text UEA Repository(Article) Nartowski, K. P., Tedder, J., Braun, D. E., Fabian, L., Khimyak, Y. Z.(2015)Building solids inside nano-space: from confined amorphous through confined solvate to confined ‘metastable’ polymorphin Physical Chemistry Chemical Physics17.pp. 24761-24773 Full Text UEA Repository(Article) Algara-Siller, G., Severin, N., Chong, S. Y., Björkman, T., Palgrave, R. G., Laybourn, A., Antonietti, M., Khimyak, Y. Z., Krasheninnikov, A. V., Rabe, J. P., Kaiser, U., Cooper, A. I., Thomas, A., Bojdys, M. J.(2014)Triazine-Based Graphitic Carbon Nitride: a Two-Dimensional Semiconductorin Angewandte Chemie International Edition53.pp. 7450-7455 Full Text UEA Repository(Article) Laybourn, A., Dawson, R., Clowes, R., Hasell, T., Cooper, A. I., Khimyak, Y. Z., Adams, D. J.(2014)Network formation mechanisms in conjugated microporous polymersin Polymer Chemistry5.pp. 6325-6333 Full Text UEA Repository(Article) Martí-Gastaldo, C., Antypov, D., Warren, J., Briggs, M., Chater, P. A., Wiper, P. V., Miller, G. J., Khimyak, Y., Darling, G. R., Berry, N. G., Rosseinsky, M. J.(2014)Sidechain control of porosity closure in multiple peptide-based porous materials by cooperative foldingin Nature Chemistry6.pp. 343-351 Full Text UEA Repository(Article) Laybourn, A., Dawson, R., Clowes, R., Iggo, J., Cooper, A., Khimyak, Y., Adams, D.(2012)Branching out with aminals: microporous organic polymers from difunctional monomersin Polymer Chemistry3.pp. 533 Full Text UEA Repository(Article) Leus, K., Vandichel, M., Liu, Y., Muylaert, I., Musschoot, J., Pyl, S., Vrielinck, H., Callens, F., Marin, G., Detavernier, C., Wiper, P., Khimyak, Y., Waroquier, M., Van Speybroeck, V., Van Der Voort, P.(2012)The coordinatively saturated vanadium MIL-47 as a low leaching heterogeneous catalyst in the oxidation of cyclohexenein Journal of Catalysis285.pp. 196-207 Full Text UEA Repository(Article) Ren, S., Bojdys, M., Dawson, R., Laybourn, A., Khimyak, Y., Adams, D., Cooper, A.(2012)Porous, Fluorescent, Covalent Triazine-Based Frameworks Via Room-Temperature and Microwave-Assisted Synthesisin Advanced Materials24.pp. 2357-2361 Full Text UEA Repository(Article) Ren, S., Dawson, R., Laybourn, A., Jiang, J., Khimyak, Y., Adams, D., Cooper, A.(2012)Functional conjugated microporous polymers: from 1,3,5-benzene to 1,3,5-triazinein Polymer Chemistry3.pp. 928-934 Full Text UEA Repository(Article) Jiang, J., Wang, C., Laybourn, A., Hasell, T., Clowes, R., Khimyak, Y., Xiao, J., Higgins, S., Adams, D., Cooper, A.(2011)Metal-Organic Conjugated Microporous Polymersin Angewandte Chemie123.pp. 1104-1107 Full Text UEA Repository(Article) Alsalme, A., Wiper, P., Khimyak, Y., Kozhevnikova, E., Kozhevnikov, I.(2010)Solid acid catalysts based on H3PW12O40 heteropoly acid: Acid and catalytic properties at a gas–solid interfacein Journal of Catalysis276.pp. 181-189 Full Text UEA Repository(Article) Rabone, J., Yue, Y., Chong, S., Stylianou, K., Bacsa, J., Bradshaw, D., Darling, G., Berry, N., Khimyak, Y., Ganin, A., Wiper, P., Claridge, J., Rosseinsky, M.(2010)An Adaptable Peptide-Based Porous Materialin Science329.pp. 1053-1057 Full Text UEA Repository(Article) Swamy, S., Bacsa, J., Jones, J., Stylianou, K., Steiner, A., Ritchie, L., Hasell, T., Gould, J., Laybourn, A., Khimyak, Y., Adams, D., Rosseinsky, M., Cooper, A.(2010)A Metal−Organic Framework with a Covalently Prefabricated Porous Organic Linkerin Journal of the American Chemical Society132.pp. 12773-12775 Full Text UEA Repository(Article)

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