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个人简介

2008-2013 University of East Anglia. RCUK Fellow on Biochemistry of Microbial Metabolism 2007-2008 University of East Anglia. Senior Research Associate on NERC-funded grant, 'Functional and molecular biodiversity of the bacterial production of the climate-changing gas deimethyl sulphide.' 2006-2007 University of East Anglia. Senior Research Associate on BBSRC-funded grant, 'Molecular analysis of gene regulators in the remarkable iron-ome of the symbiotic bacterium Rhizobium.' 2003-2006 University of East Anglia. Senior Research Associate on BBSRC-funded grant, 'Life beyond fur - novel regulators and novel targets in the iron regulon of Rhizobium.' 2000-2004 University of East Anglia. PhD, 'RirA, a novel iron-responsive regulator in the symbiotic bacterium Rhizobium leguminosarum.'

研究领域

I am a molecular microbiologist who is interested in how a broad range of microbes, both Prokaryotic and Eukaryotic, participate in biogeochemical cycling. My research group focuses on the specific mechanisms that allow such organisms to synthesise and breakdown key biological molecules and importantly regulate these processes as to allow them to sense and respond to environmental cues.

近期论文

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Johnston, A., Green, R., Todd, J.(2016)Enzymatic breakage of dimethylsulfoniopropionate - a signature molecule for life at seain Current Opinion in Chemical Biology31.pp. 58-65 Full Text UEA Repository(Article) Sun, J., Todd, J. D., Thrash, J. C., Qian, Y., Qian, M. C., Temperton, B., Guo, J., Fowler, E. K., Aldrich, J. T., Nicora, C. D., Lipton, M. S., Smith, R. D., De Leenheer, P., Payne, S. H., Johnston, A. W., Davie-Martin, C. L., Halsey, K. H., Giovannoni, S. J.(2016)The abundant marine bacterium Pelagibacter simultaneously catabolizes dimethylsulfoniopropionate to the gases dimethyl sulfide and methanethiolin Nature Microbiology1. Full Text UEA Repository(Article) Carrion Fonseca, O., Curson, A., Kumaresan, D., Fu, Y., Lang, A., Mercadé, E., Todd, J.(2015)A novel pathway producing dimethylsulphide in bacteria is widespread in soil environmentsin Nature Communications6. Full Text UEA Repository(Article) Brummett, A. E., Schnicker, N. J., Crider, A., Todd, J., Dey, M.(2015)Biochemical, Kinetic, and Spectroscopic Characterization of Ruegeria pomeroyi DddW-A Mononuclear Iron-Dependent DMSP Lyasein PLoS ONE10. Full Text UEA Repository(Article) Curson, A., Burns, O., Voget, S., Daniel, R., Todd, J., McInnis, K., Wexler, M., Johnston, A.(2014)Screening of Metagenomic and Genomic Libraries Reveals Three Classes of Bacterial Enzymes That Overcome the Toxicity of Acrylate UEA Repository(Paper)Curson, A. R. J., Burns, O. J., Voget, S., Daniel, R., Todd, J. D., McInnis, K., Wexler, M., Johnston, A. W. B.(2014)Screening of Metagenomic and Genomic Libraries Reveals Three Classes of Bacterial Enzymes That Overcome the Toxicity of Acrylatein PLoS ONE9. Full Text UEA Repository(Article) Green, R., Todd, J., Johnston, A.(2013)Manganese uptake in marine bacteria; the novel MntX transporter is widespread in Roseobacters, Vibrios, Alteromonadales and the SAR11 and SAR116 cladesin The ISME Journal7.pp. 581-591 Full Text UEA Repository(Article) Todd, J., Kirkwood, M., Newton-Payne, S., Johnston, A.(2012)DddW, a third DMSP lyase in a model Roseobacter marine bacterium, Ruegeria pomeroyi DSS-3in The ISME Journal6.pp. 223-226 Full Text UEA Repository(Article) Curson, A., Fowler, E., Dickens, S., Johnston, A., Todd, J.(2012)Multiple DMSP lyases in the γ-proteobacterium Oceanimonas doudoroffiiin Biogeochemistry110.pp. 109-119 Full Text UEA Repository(Article) Sun, L., Curson, A., Todd, J., Johnston, A.(2012)Diversity of DMSP transport in marine bacteria, revealed by genetic analysesin Biogeochemistry110.pp. 121-130 Full Text UEA Repository(Article) Todd, J., Curson, A., Sullivan, M., Kirkwood, M., Johnston, A.(2012)The Ruegeria pomeroyi acuI Gene Has a Role in DMSP Catabolism and Resembles yhdH of E. coli and Other Bacteria in Conferring Resistance to Acrylatein PLoS ONE7. Full Text UEA Repository(Article) Curson, A., Todd, J., Sullivan, M., Johnston, A.(2011)Catabolism of dimethylsulphoniopropionate: microorganisms, enzymes and genesin Nature Reviews Microbiology9.pp. 849-859 Full Text UEA Repository(Article) White, G., Singleton, C., Todd, J., Cheesman, M., Johnston, A., Le Brun, N.(2011)Heme binding to the second, lower-affinity site of the global iron regulator Irr from Rhizobium leguminosarum promotes oligomerizationin FEBS Journal278.pp. 2011-2021 Full Text UEA Repository(Article) Todd, J., Curson, A., Kirkwood, M., Sullivan, M., Green, R., Johnston, A.(2011)DddQ, a novel, cupin-containing, dimethylsulfoniopropionate lyase in marine roseobacters and in uncultured marine bacteriain Environmental Microbiology13.pp. 427-438 Full Text UEA Repository(Article) Sullivan, M., Curson, A., Shearer, N., Todd, J., Green, R., Johnston, A.(2011)Unusual regulation of a leaderless operon involved in the catabolism of dimethylsulfoniopropionate in Rhodobacter sphaeroidesin PLoS ONE6. Full Text UEA Repository(Article) Curson, A., Sullivan, M., Todd, J., Johnston, A.(2011)DddY, a periplasmic dimethylsulfoniopropionate lyase found in taxonomically diverse species of Proteobacteriain The ISME Journal5.pp. 1191-1200 Full Text UEA Repository(Article) Singleton, C., White, G., Todd, J., Marritt, S., Cheesman, M., Johnston, A., Le Brun, N.(2010)Heme-responsive DNA binding by the global iron regulator Irr from Rhizobium leguminosarumin The Journal of Biological Chemistry285.pp. 16023-16031 Full Text UEA Repository(Article) Kirkwood, M., Le Brun, N., Todd, J., Johnston, A.(2010)The dddP gene of Roseovarius nubinhibens encodes a novel lyase that cleaves dimethylsulfoniopropionate into acrylate plus dimethyl sulfidein Microbiology156.pp. 1900-1906 Full Text UEA Repository(Article) Kirkwood, M., Le Brun, N., Todd, J., Johnston, A.(2010)The ddP gene of Roseovarius nubinhibens encodes a novel lyase that cleaves dimethylsulfoniopropionate into acrylate plus dimethyl sulfidein Microbiology156.pp. 1900-1906 UEA Repository(Article) Todd, J., Curson, A., Nikolaidou-Katsaraidou, N., Brearley, C., Watmough, N., Chan, Y., Bulman Page, P., Sun, L., Johnston, A.(2010)Molecular dissection of bacterial acrylate catabolism - unexpected links with dimethylsulfoniopropionate catabolism and dimethyl sulfide productionin Environmental Microbiology12.pp. 327-343 Full Text UEA Repository(Article)

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