Mogensen, Mette - University of East Anglia - School of Biological Sciences

个人简介

Senior Lecturer in Cell and Developmental Biology, UEA (2009 - present) Lecturer in Cell and Developmental Biology, UEA (2001- 2009) Welcome Trust Lecturer / Research Fellow, Univ of Dundee. (1997-2000) Senior Postdoctoral Research Associate, Univ of St. Andrews (1991-1997) Postdoctoral Research Associate, University of St. Andrews (1985-1991) Demonstrator in Cell Biology, University of Manchester (1983-1985) Education Post Graduate Certificate in Higher Education Practice (2004) Ph.D. in Cell Biology, University of Manchester (1985) B.Sc. in Genetics and Cell Biology, University of Manchester (1980)

研究领域

Our research is concerned with the cytoskeleton in health and disease with a main focus on microtubule and centrosome reorganization during epithelial differentiation. The aims are to determine the mechanisms and molecular bases for the generation and maintenance of non-centrosomal apico-basal microtubules arrays in polarised epithelial cells. The studies address basic cell biological problems as well as issues of importance for advancing our understanding of cancer. Lab.

近期论文

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Goldspink, D., Gadsby, J., Bellett, G., Keynton, J., Tyrrell, B., Lund, E., Powell, P., Thomas, P., Mogensen, M.(2013)The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiationin Journal of Cell Science126.pp. 4000-4014 Full Text UEA Repository(Article) Zhou, Z., Mogensen, M. M., Powell, P. P., Curry, S., Wileman, T., Microscopy, Fluorescence(2013)Foot-and-mouth disease virus 3C protease induces fragmentation of the Golgi compartment and blocks intra-Golgi transportin Journal of Virology87.pp. 11721-11729 Full Text UEA Repository(Article) Bellett, G., Carter, J., Keynton, J., Goldspink, D., James, C., Moss, D., Mogensen, M.(2009)Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cellsin Cell Motility and the Cytoskeleton66.pp. 893-908 Full Text UEA Repository(Article) Kohlmaier, G., Loncarek, J., Meng, X., McEwen, B., Mogensen, M., Spektor, A., Dynlacht, B., Khodjakov, A., Gonczy, P.(2009)Overly Long Centrioles and Defective Cell Division upon Excess of the SAS-4-Related Prootein CPAPin Current Biology19.pp. 1012-1018 Full Text UEA Repository(Article) Wagstaff, L., Bellett, G., Mogensen, M., Munsterberg, A.(2008)Multicellular rosette formation during cell ingression in the avian primitive streakin Developmental Dynamics237.pp. 91-96 Full Text UEA Repository(Article) Dahm, R., Procter, J., Ireland, M., Lo, W., Mogensen, M., Quinlan, R., Prescott, A.(2007)Reorganisation of centrosomal marker proteins coincides with epithelial cell differentiation in vertebrate lensin Experimental Eye Research85.pp. 696-713 Full Text UEA Repository(Article) Hoppeler-Lebel, A., Celati, C., Bellett, G., Mogensen, M., Klein-Hitpass, L., Bornens, M., Tassin, A.(2007)Centrosomal CAP350 protein stabilises microtubule associated with the Golgi complexin Journal of Cell Science120.pp. 3299-3308 Full Text UEA Repository(Article) Mogensen, M., Rzadzinska, A., Steel, K.(2007)The deaf mouse mutant whirler suggests a role for whirlin in actin filament dynamics and sterocilia development.in Cell Motility and the Cytoskeleton64.pp. 496-508 Full Text UEA Repository(Article) Moss, D., Bellett, G., Carter, J., Liovic, M., Keynton, J., Prescott, A., Lane, E., Mogensen, M.(2007)Ninein is released from the centrosome and moves bi-directionally along microtubulesin Journal of Cell Science120.pp. 3064-3074 Full Text UEA Repository(Article) Baird, D., Myers, K., Mogensen, M., Moss, D., Baas, P.(2004)Distribution of the microtubule-related protein ninein in developing neurons.in Neuropharmacology47.pp. 677-683 Full Text UEA Repository(Article) Mogensen, M.(2004)Microtubule organizing centers in polarized epithelial cells.Wiley-VCH, Weinheimpp. 299-312 Full Text UEA Repository(Chapter)Gromley, A., Jurczyk, A., Sillibourne, J., Halilovic, E., Mogensen, M., Groisman, I., Blomberg, M., Doxsey, S.(2003)A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase.in Journal of Cell Biology161.pp. 535-545 Full Text UEA Repository(Article) Keryer, G., Di Fiore, B., Celati, C., Lechtreck, K., Mogensen, M., Delouvee, A., Lavia, P., Bornens, M., Tassin, A.(2003)Part of Ran is associated with AKAP450 at the Centrosome: Involvement in microtubule-organizing activity.in Molecular Biology of the Cell14.pp. 4260-4271 Full Text UEA Repository(Article) Keryer, G., Di Fiore, B., Celati, C., Lechtreck, K., Mogensen, M., Delouvee, A., Lavia, P., Bornens, M., Tassin, A.(2003)Ran is associated with the centrosome through AKAP450 during interphase: Involvement in microtubule nucleation.in Cell Motility and the Cytoskeleton54.pp. 51 UEA Repository(Article) Liovic, M., Mogensen, M., Prescott, A., Lane, E.(2003)Observation of keratin particles showing fast bidirectional movement colocalized with microtubules.in Journal of Cell Science116.pp. 1417-1427 Full Text UEA Repository(Article) Moss, D., Bellett, G., Liovic, M., Piel, M., Prescott, A., Lane, E., Bornens, M., Mogensen, M.(2003)Two functionally distinct centrosomal complexes are responsible for microtubule nucleation and anchorage.in Cell Motility and the Cytoskeleton54.pp. 40 UEA Repository(Article) Abal, M., Piel, M., Bouckson-Castaing, V., Mogensen, M., Sibarita, J., Bornens, M.(2002)Microtubule release from the centrosome in migrating cells.in Journal of Cell Biology159.pp. 731-737 Full Text UEA Repository(Article) Gromley, A., Blomberg-Wirschell, M., Groisman, I., Mogensen, M., Craig, R., Powers, C., Doxsey, S.(2002)A mammalian centriole protein homologous to a component of the mitotic exit network plays a role in completion of cytokinesis, cell cycle progression and microtubule organization.in Molecular Biology of the Cell12.pp. 2256 UEA Repository(Article) Mogensen, M., Tucker, J., Mackie, J., Prescott, A., Nathke, I.(2002)Involvement of the Adenomatous Polyposis Coli Protein in establishing polar microtubule arrays in the inner ear epithelium.in Molecular Biology of the Cell12.pp. 266 UEA Repository(Article) Mogensen, M., Tucker, J., Mackie, J., Prescott, A., Nathke, I.(2002)The adenomatous polyposis coli protein unambiguously localizes to microtubule plus-ends and is involved in establishing parallel arrays of microtubule bundles in highly polarised epithelial cellsin Journal of Cell Biology157.pp. 1041-1048 Full Text UEA Repository(Article)