Gavrilovic, Jelena - University of East Anglia - School of Biological Sciences

个人简介

Senior Lecturer in Cell Biology, University of East Anglia (2002-present; full-time since 2014) Lecturer in Cell Biology (75% time), University of East Anglia (1997-2002) Group Leader (60% time) Strangeways Research Laboratory (1994-1997) Post-doctoral Associate (50% time) , Strangeways Research Laboratory, Cambridge (1993-1994) One-year career break after birth of first child (1992-1993) Post-doctoral Fellow, University College London (1989-1992) Royal Society and EMBO Post-doctoral Fellow Ecole Normale Superieure, Paris, France(1987-1989) Ph.D. - Strangeways Research Laboratory, Cambridge (1987) B.Sc. - Cell Biology, University College London (1978)

研究领域

Our interests lie in cell-cell and cell-matrix interactions in health and disease, with an emphasis on inflammation. We have some focus on how metalloproteinases of the MMP, ADAM and ADAMTS families may modulate these interactions.

近期论文

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Bevan, D., Baker, N., Goldring, M., Donell, S., Gavrilovic, J.(2016)Chondrocyte responses to neurovascular peptides, cytokines, and a 3D environment: focus on ADAMsin Metalloproteinases in Medicine3.pp. 63-74 Full Text UEA Repository(Article) Kelwick, R., Wagstaff, L., Decock, J., Roghi, C., Cooley, L. S., Robinson, S. D., Arnold, H., Gavrilovic, J., Jaworski, D. M., Yamamoto, K., Nagase, H., Seubert, B., Krüger, A., Edwards, D. R.(2015)Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15: ADAMTS-15 Inhibits Breast Cancer Cell Migrationin International Journal of Cancer136.pp. E14–E26 Full Text UEA Repository(Article) Murray, M., Birkland, T., Howe, J., Rowan, A. D., Fidock, M., Parks, W., Gavrilovic, J.(2013)Macrophage Migration and Invasion Is Regulated by MMP10 Expressionin PLoS ONE8. Full Text UEA Repository(Article) Baker, N., Sharpe, P., Culley, K., Otero, M., Bevan, D., Newham, P., Barker, W., Clements, K., Langham, C., Goldring, M., Gavrilovic, J.(2012)Dual regulation of metalloproteinase expression in chondrocytes by Wnt-1–inducible signaling pathway protein 3/CCN6in Arthritis & Rheumatism64.pp. 2289–2299 Full Text UEA Repository(Article) Galindo, F., Kabir, N., Gavrilovic, J., Russell, D.(2008)Spectroscopic studies of 1,2-diaminoanthraquinone (DAQ) as a fluorescent probe for the imaging of nitric oxide in live cellsin Photochemical & Photobiological Sciences7.pp. 126-130 Full Text UEA Repository(Article) Zhong, J., Poghosyan, Z., Pennington, C., Scott, X., Handsley, M., Warn, A., Gavrilovic, J., Honert, K., Kruger, A., Span, P., Sweep, F., Edwards, D.(2008)Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinomain Molecular Cancer Research6.pp. 383-394 Full Text UEA Repository(Article) Worley, J., Hughes, D., Dozio, N., Gavrilovic, J., Sampson, M.(2007)Low density lipoprotein from patients with Type 2 diabetes increases expression of monocyte matrix metalloproteinase and ADAM metalloproteinase genesin Cardiovascular Diabetology6.pp. 21 Full Text UEA Repository(Article) Sampson, M., Wall, S., Baugh, M., Worley, J., Davies, I., Hughes, D., Gavrilovic, J.(2006)Monocyte matrix and ADAM metalloproteinase expression in type 2 diabetes after aspirin therapy.in Diabetes Research and Clinical Practice71.pp. 45-51 Full Text UEA Repository(Article) Wieder, M., Hone, D., Cook, M., Handlsey, M., Gavrilovic, J., Russell, D.(2006)Intracellular Photodynamic Therapy with Photosensitizer-Nanoparticle Conjugates: Cancer Therapy Using a 'Trojan Horse'in Photochemical & Photobiological Sciences5.pp. 727-734 Full Text UEA Repository(Article) Galindo, F., Burguete, M. I., Vigara, L., Luis, S. V., Kabir, N., Gavrilovic, J., Russell, D. A.(2005)Synthetic Macrocyclic Peptidomimetics as Tunable pH Probes for the Fluorescence Imaging of Acidic Organelles in Live Cellsin Angewandte Chemie-International Edition44.pp. 6504-6508 Full Text UEA Repository(Article) Singh, R., Mason, J., Lidington, E., Edwards, D., Nuttall, R., Khokha, R., Knauper, V., Murphy, G., Gavrilovic, J.(2005)Cytokine stimulated vascular cell adhesion molecule-1 (VCAM-1) ectodomain release is regulated by TIMP-3.in Cardiovascular Research67.pp. 39-49 Full Text UEA Repository(Article) Sampson, M., Davies, I., Gavrilovic, J., Sussams, B., Brown, J., Astley, S., Hughes, D.(2004)Plasma matrix metalloproteinases, low density lipoprotein oxidisability and soluble adhesion molecules after a glucose load in Type 2 diabetesin Cardiovascular Diabetology3.pp. 7 Full Text UEA Repository(Article) Harrison, M., Abu-elmagd, M., Grocott, T., Yates, C., Gavrilovic, J., Wheeler, G. N.(2004)Matrix metalloproteinase genes inXenopus developmentin Developmental Dynamics231.pp. 214-220 Full Text UEA Repository(Article) Baugh, M., Gavrilovic, J., Davies, I., Hughes, D., Sampson, M.(2003)Monocyte matrix metalloproteinase production in Type 2 diabetes and controls - a cross sectional study.in Cardiovascular Diabetology2.pp. 1-4 Full Text UEA Repository(Article) Platt, C., Krekoski, C., Edwards, D., Gavrilovic, J.(2003)Extracellular matrix and matrix metalloproteinases in sciatic nerve.in Journal of Neuroscience Research74.pp. 417-429 Full Text UEA Repository(Article) Worley, J., Baugh, M., Hughes, D., Edwards, D., Hogan, A., Sampson, M., Gavrilovic, J.(2003)Metalloproteinase expression in PMA stimulated THP-1 cells: effects of peroxisome proliferator-activated receptor-y (PPARy) agonists and 9-cis-retionic acid.in Journal of Biological Chemistry278.pp. 51340-51346 Full Text UEA Repository(Article) Stringa, E., White, D., Tuan, R., Knauper, V., Gavrilovic, J.(2002)Role of newly synthesized fibronectin in vascular smooth muscle cell migration on matrix-metalloproteinase-degraded collagen.in Biochemical Society Transactions30.pp. 102-111 Full Text UEA Repository(Article) Tamiya, S., Wormstone, I., Marcantonio, J., Gavrilovic, J., Duncan, G.(2000)Induction of Matrix Metalloproteinases 2 and 9 following Stress to the Lensin Experimental Eye Research71.pp. 591-597 Full Text UEA Repository(Article) Murphy, G., Knäuper, V., Atkinson, S., Gavrilovic, J., Edwards, D.(2000)Cellular mechanisms for focal proteolysis and the regulation of the microenvironmentin Fibrinolysis and Proteolysis14.pp. 165-174 Full Text UEA Repository(Article)