Kelemen, Gabriella - University of East Anglia - School of Biological Sciences

个人简介

Senior Lecturer, University of East Anglia (2014-present) Lecturer, University of East Anglia (2000-present) Post Doctoral Fellow, John Innes Centre (1993-2000) Post Doctoral Fellow, University of Leicester (1991-1993) Leverhulme Trust Fellowship, University of Leicester, Department of Biochemistry (1989-1990) Ph.D. - Eötvös Loránd University Budapest, Hungary (1987) B.Sc. - Chemistry; Eötvös Loránd University Budapest, Hungary (1984)

研究领域

Our main research interest is studying bacterial development of Streptomyces coelicolor, a Gram-positive, filamentous bacterium. Unlike most bacteria that divide by binary fission, in Streptomyces coelicolor long, multigenomic filaments are formed with ocasional septa and regular branching. Cell division is completed only during sporulation when 50-100 sporulation septa are laid down synchronously in the aerial hyphae generating unigenomic spore compartments.

近期论文

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Tzanis, A., Dalton, K. A., Hesketh, A., Den Hengst, C. D., Buttner, M. J., Thibessard, A., Kelemen, G. H.(2014)A sporulation specific, sigF -dependent protein, SspA, affects septum positioning inin Molecular Microbiology91.pp. 363-380 Full Text UEA Repository(Article) Holmes, N., Walshaw, J., Leggett, R., Thibessard, A., Dalton, K., Gillespie, M., Hemmings, A., Gust, B., Kelemen, G.(2013)Coiled-coil protein Scy is a key component of a multiprotein assembly contrlling polarized growth in Streptomycesin Proceedings of the National Academy of Sciences of the United States of America (PNAS)110.pp. 397-406 UEA Repository(Article) Ditkowski, B., Holmes, N., Rydzak, J., Donczew, M., Bezulska, M., Ginda, K., Kedzierski, P., Zakrzewska-Czerwinska, J., Kelemen, G., Jakimowicz, D.(2013)Dynamic interplay of ParA with the polarity protein, Scy, coordinates growth with chromosome segregation in Streptomyces coelicolorin Open Biology3. Full Text UEA Repository(Article) Walshaw, J., Gillespie, M., Kelemen, G.(2010)A novel coiled-coil repeat variant in a class of bacterial cytoskeletal proteinsin Journal of Structural Biology170.pp. 202-215 Full Text UEA Repository(Article) Leggett, R., Grandison, S., Morris, R., Kelemen, G., Moulton, V.(2009)Statistical analysis of the growth and morphology of the filamentous microbe Streptomyces coelicolor.(Other)Gaskell, A., Crack, J., Cheeseman, M., Kelemen, G., Hutchings, M., Le Brun, N.(2007)RsmA, an anti-sigma factor from Streptomyces coelicolor, modulates its activity through a [2Fe-2s] cluster cofactorin Journal of Biological Chemistry282.pp. 31812-31820 Full Text UEA Repository(Article) Dalton, K., Thibessard, A., Hunter, J., Kelemen, G.(2007)A novel compartment, the 'subqpical stem' of the aerial hyphae, is the location of a sigN-dependent, developmentally distinct transcription in Streptomyces coelicolor.in Molecular Microbiology64.pp. 719-737 Full Text UEA Repository(Article) Hunt, A., Servin-Gonzalez, L., Kelemen, G., Buttner, M.(2005)The bldC developmental locus of Streptomyces coelicolor encodes a member of a family of small DNA-binding proteins related to the DNA-binding domains of the MerR family.in Journal of Bacteriology187.pp. 716-728 Full Text UEA Repository(Article) Traag, B., Kelemen, G., van Wezel, G.(2004)Transcription of the sporulation gene ssgA is activated by the IcIR-type regulator SsgR in a whi-independent manner in Streptomyces coelicolor A3(2).in Molecular Microbiology53.pp. 985-1000 Full Text UEA Repository(Article) Viollier, P., Kelemen, G., Dale, G., Nguyen, K., Buttner, M., Thompson, C.(2003)Specialized osmotic stress response systems involve multiple SigB-like sigma factors in Streptomyces coelicolor.in Molecular Microbiology47.pp. 699-714 Full Text UEA Repository(Article) Kelemen, G., Viollier, P., Tenor, J., Marri, L., Buttner, M., Thompson, C.(2001)A connection between stress and development in the multicelular prokaryote Streptomyces coelicolor.in Molecular Microbiology40.pp. 804-814 Full Text UEA Repository(Article)