Munsterberg, Andrea - University of East Anglia - School of Biological Sciences

个人简介

Since 2010 Professor of Developmental Biology Reader in Developmental Biology, University of East Anglia, (2006 – 2010) Senior Lecturer in Developmental Biology, University of East Anglia (2001-2006) Wellcome Trust Career Development Fellow, University of Dundee (1997-2001) Lecturer and Principal Investigator, University of Dundee (1996-1997) MDA Postdoctoral Fellow, Harvard Medical School, Boston, USA (1994-1996) HFSPO Postdoctoral Fellow, Harvard Medical School, Boston, USA (1992-1994) Ph.D. - National Institute for Medical Research, MRC, Mill Hill, London (1992) German Diploma - Biology, University of Heidelberg (1988)

研究领域

My group investigates cellular and molecular mechanisms that underlie embryonic development. We use the chick embryo as a vertebrate model organism and are particularly interested in the signals that control cell fate decisions. For example, developing somites give rise to skeletal muscle, cartilage, bone and tendon. How are these different cell types specified? in the developing heart we have characterized the origin and migration of cells that contribute to different parrts of this important tissue. The mechanistic insights obtained do not only increase our understanding of early embryo development, but also impact areas such as stem cell science and regenerative medicine.

近期论文

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Grocott, T., Thomas, P., Munsterberg, A.(2016)Atlas Toolkit: Fast registration of 3D morphological datasets in the absence of landmarksin Scientific Reports6. Full Text UEA Repository(Article) Giusti, J., Pinhal, D., Moxon, S., Lovaglio Campos, C., Munsterberg, A., Martins, C.(2016)MicroRNA-10 modulates Hox genes expression during Nile tilapia embryonic developmentin Mechanisms of Development140.pp. 12-18 Full Text UEA Repository(Article) Wittig, J., Munsterberg, A.(2016)The early stages of heart development: insights from chicken embryosin Journal of Cardiovascular Development and Disease3. Full Text UEA Repository(Article) Lu, W., Shi, Y., Ma, Z., Wang, G., Liu, L., Chuai, M., Song, X., Munsterberg, A., Cao, L., Yang, X.(2016)Proper autophagy is indispensable for angiogenesis during chick embryo developmentin Cell Cycle15.pp. 1742-1754 Full Text UEA Repository(Article) Hatch, V., Marin Barba, M., Moxon, S., Ford, C., Ward, N., Tomlinson, M., Desanlis, I., Hendry, A., Hontelez, S., van Krujsbergen, I., Veenstra, G. J., Munsterberg, A., Wheeler, G.(2016)The positive transcriptional elongation factor (P-TEFb) is required for neural crest specificationin Developmental Biology416.pp. 361–372 Full Text UEA Repository(Article) Abu-Elmagd, M., Goljanek-Whysall, K., Wheeler, G., Munsterberg, A.(2015)Sprouty2 mediated tuning of signalling is essential for somite myogenesisin BMC Medical Genomics8. Full Text UEA Repository(Article) About-Elhamd, A., Alrefaei, A., Mok, G. F. (., Garcia-Morales, C., Abu-Elmagd, M., Wheeler, G., Munsterberg, A.(2015)Klhl31 attenuates β-catenin dependent Wnt signaling and regulates embryo myogenesisin Developmental Biology402.pp. 61-71 Full Text UEA Repository(Article) Ahmed, A., Ward, N. J., Moxon, S., Lopez-Gomollon, S., Viaut, C., Tomlinson, M. L., Patrushev, I., Gilchrist, M. J., Dalmay, T., Dotlic, D., Munsterberg, A. E., Wheeler, G. N.(2015)A Database of microRNA Expression Patterns in Xenopus laevisin PLoS ONE10. Full Text UEA Repository(Article) Reynolds, A., Wharton, N., Parris, A., Mitchell, E., Sobolewski, A., Kam, C., Bigwood, L., El Hadi, A., Münsterberg, A., Lewis, M., Speakman, C., Stebbings, W., Wharton, R., Sargen, K., Tighe, R., Jamieson, C., Hernon, J., Kapur, S., Oue, N., Yasui, W., Williams, M., Aged, 80 and over, Microscopy, Confocal(2014)Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epitheliumin Gut63.pp. 610-621 Full Text UEA Repository(Article) Song, J., Mccoll, J., Camp Navarro, E., Kennerley, N., Mok, G., Mccormick, D., Grocott, T., Wheeler, G., Munsterberg, A.(2014)Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cellsin Proceedings of the National Academy of Sciences111.pp. 7337-7342 Full Text UEA Repository(Article) Goljanek-Whysall, K., Mok, G. F., Alrefaei, A., Kennerley, N., Wheeler, G., Munsterberg, A.(2014)myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesisin Development141.pp. 3378-3387 Full Text UEA Repository(Article) Li, Y., Wang, X., Ma, Z., Chuai, M., Munsterberg, A., Lee, K. K., Yang, X.(2014)Endoderm contributes to endocardial composition during cardiogenesisin Chinese Science Bulletin59.pp. 2749-2755 Full Text UEA Repository(Article) Wang, X., Li, Y., Wang, G., Munsterberg, A., Chuai, M., Lee, K., Wang, L., Yang, X.(2014)Combinational electroporation and transplantation approach of studying gene functions in avian embryos.in Chinese Science Bulletin59.pp. 616-624 Full Text UEA Repository(Article) Wang, X., Li, Y., Ma, Z., Wang, L., Chuai, M., Munsterberg, A., Geng, J., Yang, X.(2013)Retention of stem cell plasticity in avian primitive streak cells and the effects of local micro-environmentin The Anatomical Record296.pp. 533-543 Full Text UEA Repository(Article) Goljanek-Whysall, K., Pais, H., Rathjen, T., Sweetman, D., Dalmay, T., Munsterberg, A.(2012)Regulation of multiple target genes by miR-1 and miR-206 is pivotal for C2C12 myoblast differentiationin Journal of Cell Science125.pp. 3590-3600 Full Text UEA Repository(Article) Swingler, T., Wheeler, G., Carmont, V., Elliott, H., Barter, M., Abu-Elmagd, M., Donell, S., Boot-Handford, R., Hajihosseini, M., Munsterberg, A., Dalmay, T., Young, D., Clark, I.(2012)The expression and function of microRNAs in chondrogenesis and osteoarthritisin Arthritis & Rheumatism64.pp. 1909-1919 Full Text UEA Repository(Article) Goljanek-Whysall, K., Sweetman, D., Munsterberg, A.(2012)microRNAs in skeletal muscle differentiation and diseasein Clinical Science123.pp. 611-625 Full Text UEA Repository(Article) Goljanek-Whysall, K., Sweetman, D., Abu-Elmagd, M., Chapnik, E., Dalmay, T., Hornstein, E., Munsterberg, A.(2011)MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesisin Proceedings of the National Academy of Sciences108.pp. 11936-11941 Full Text UEA Repository(Article) Camp Navarro, E., Munsterberg, A.(2011)Ingression, migration and early differentiation of cardiac progenitorsin Frontiers in Bioscience-Landmark16.pp. 2416-2426 Full Text UEA Repository(Article) Swingler, T., Nicolas, F., Soond, S., Munsterberg, A.(2011)Identification and characterisation of microRNAs involved in chondrocyte differentiation and osteoarthritis()