Hernandez, Noemi Tejera - University of East Anglia - Department of Nutrition and Preventive Medicine

个人简介

Senior Research Associate in Nutrition Department, University of East Anglia, UK, 2012 Postdoctoral Fellow Vanderbilt University, Pharmacology Department, USA, 2009-2012 Postdoctoral Fellow University of La Laguna, Department of Animal Physiology, Spain, 2008 Research Associate/Assistant, University of La Laguna, Department of Animal Physiology, Spain, 2001-2007 Academic Background Ph.D. University of La Laguna, Spain- 2007. Diploma of Advanced Studies, University of La Laguna, Spain- 2004. BSc. in Biological Sciences. University of La Laguna, Spain- 2001.

研究领域

Alternative sources of Long chain Omega 3 fatty acids Arachidonic acid, EPA and DHA and human health Lipid Metabolism Biomarkers of inflammation Lipidomics The main goal of my studies is to compare the impact of equivalent doses of EPA and DHA fed either as fish oils or vegetable oil on plasma and tissue fatty acid enrichment and vascular performance in both a rodent model and a human pilot study. Also, given the importance of lipid mediators as biomarkers of oxidative stress, inflammation and resolution of inflammation, my research it is focused into develop a method for the analysis of several of these biomarkers in biological samples. These results are expected to give us a first insight of the physiological impact of plant derived long chain n-3 PUFA and a better understanding on lipid metabolism. At present, I also co-lead Objective 4 of the BBSRC ISP, known as COB Study (n=240 participants, 2013-2014). COB is the first comprehensive investigation of the impact of age, sex, genetic make-up and gut microflora composition on flavonoids’ absorption, distribution, metabolism and elimination in humans. We expect the results obtained in this study to significantly advance our current understanding of factors which modulate flavonoid absorption and metabolism and provide insight into which individuals are most likely to benefit from increased flavonoid and fruits and vegetable intake.

近期论文

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Tejera, N., Vauzour, D., Betancor, M. B., Sayanova, O., Usher, S., Cochard, M., Rigby, N., Ruiz-Lopez, N., Menoyo, D., Tocher, D. R., Napier, J. A., Minihane, A. M.(2016)A transgenic Camelina sativa seed oil effectively replaces fish oil as a dietary source of eicosapentaenoic acid in micein Journal of Nutrition146.pp. 227-235 Full Text UEA Repository(Article) McManus, S., Tejera, N., Awwad, K., Vauzour, D., Rigby, N., Fleming, I., Cassidy, A., Minihane, A.(2016)Differential effects of EPA vs. DHA on postprandial vascular function and the plasma oxylipin profile in menin The Journal of Lipid Research57.pp. 1720-1727 Full Text UEA Repository(Article) Vauzour, D., Tejera, N., O'Neill, C., Booz, V., Jude, B., Wolf, I. M., Rigby, N., Silvan, J. M., Curtis, P. J., Cassidy, A., De Pascual-Teresa, S., Rimbach, G., Minihane, A.(2015)Anthocyanins do not influence long-chain n-3 fatty acid status: Studies in cells, rodents and humansin Journal of Nutritional Biochemistry26.pp. 211-218 Full Text UEA Repository(Article) McElroy, S. J., Hobbs, S., Kallen, M., Tejera Hernandez, N., Rosen, M. J., Grishin, A., Matta, P., Schneider, C., Upperman, J., Ford, H., Polk, D. B., Weitkamp, J., Receptor, Epidermal Growth Factor(2012)Transactivation of EGFR by LPS induces COX-2 expression in enterocytesin PLoS ONE7. Full Text UEA Repository(Article) Tejera Hernandez, N., Boeglin, W., Suzuki, T., Schneider, C.(2012)COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytesin The Journal of Lipid Research53.pp. 87-94 Full Text UEA Repository(Article) Griesser, M., Pistis, V., Suzuki, T., Tejera, N., Pratt, D. A., Schneider, C., Cell Transformation, Neoplastic, Cells, Cultured(2011)Autoxidative and Cyclooxygenase-2 Catalyzed Transformation of the Dietary Chemopreventive Agent Curcuminin Journal of Biological Chemistry286.pp. 1114-1124 Full Text UEA Repository(Article) Griesser, M., Suzuki, T., Tejera Hernandez, N., Mont, S., Boeglin, W. E., Pozzi, A., Schneider, C., Cells, Cultured(2011)Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathwaysin Proceedings of the National Academy of Sciences of the United States of America (PNAS)108.pp. 6945-6950 Full Text UEA Repository(Article) Tejera, N., Cejas, J. R., Rodríguez, C., Jerez, S., Pérez, J. A., Felipe, B. C., Lorenzo, A.(2010)Pigmentation, carotenoids, lipid peroxides and lipid composition of red porgy (Pagrus pagrus) skin reared under open-cage conditionsin Aquaculture Research41.pp. 1043–1053 Full Text UEA Repository(Article) Mulugeta, S., Suzuki, T., Hernandez, N. T., Griesser, M., Boeglin, W. E., Schneider, C.(2010)Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2in The Journal of Lipid Research51.pp. 575-585 Full Text UEA Repository(Article) Tejera, N., Cejas, J. R., Rodríguez, C., Bjerkeng, B., Jerez, S., Bolaños, A., Lorenzo, A.(2007)Pigmentation, carotenoids, lipid peroxides and lipid composition of skin of red porgy (Pagrus pagrus) fed diets supplemented with different astaxanthin sourcesin Aquaculture270.pp. 218-230 Full Text UEA Repository(Article) Almansa, E., Domingues, P., Sykes, A., Tejera, N., Lorenzo, A., Andrade, J. P.(2006)The effects of feeding with shrimp or fish fry on growth and mantle lipid composition of juvenile and adult cuttlefish (Sepia officinalis)in Aquaculture256.pp. 403-413 Full Text UEA Repository(Article) Cejas, J. R., Almansa, E., Tejera Hernandez, N., Jerez, S., Bolaños, A., Lorenzo, A.(2003)Effect of dietary supplementation with shrimp on skin pigmentation and lipid composition of red porgy (Pagrus pagrus) alevinsin Aquaculture218.pp. 457-469 Full Text UEA Repository(Article)