Muller, Michael - University of East Anglia - Department of Nutrition and Preventive Medicine

个人简介

Professor Michael Müller is Director of the Norwich Research Park Food and Health Alliance and a Professor of Nutrigenomics and Systems Nutrition. He is a renowned expert in the area of molecular nutrition related to lipid homeostasis, nutrigenomics and nutritional systems biology and his work is focussed on the molecular mechanisms underlying genome-wide effects of foods (specific bioactive components or nutrients) on immuno-metabolic health and plasticity. Professor Muller was a member of the editorial boards of numerous journals, i.e. “BMC Genomics” (associate editor), "European Journal of Nutrition" (section editor "Nutrigenomics") and “PLOS One” (academic editor), visiting professor at Nanijng Agricultural University and (co)author of more than 230 peer-reviewed publications with more than 10500 citations. As promoter he has supervised 24 PhD students, has an H-factor of 59 and is a member of the “Faculty of 1000” (Biology/Physiology). Career History 1988 – 1994 German Cancer Research Center, Division of Tumorbiochemistry, Heidelberg/Germany. Postdoctoral fellow and scientific employee at the German Cancer Research Center. 1994 - Nov 2000 University Hospital Groningen, Division of Gastroenterology and Hepatology, Groningen/The Netherlands. Associate professor, senior scientist and research leader (“Regulation of transport proteins in normal and diseased liver”) 2000 – 2013 University Wageningen, Nutrition, Metabolism and Genomics group, Wageningen/ The Netherlands. Full professor and Chair of Nutrition, Metabolism and Genomics at Wageningen University/The Netherlands. From 2003-2009 he was Scientific Director of the Nutrigenomics Consortium. From 2010-2013 he was Scientific Director of the Netherlands Nutrigenomics Center. He was board member of the NUGO. 2014 – now University of East Anglia Norwich/UK. Full Professor at the Norwich Medical School (Molecular Nutrition and Nutrigenomics) and Director of the Food and Health Alliance (FAHA; Norwich Research Park). He is also interim director of NUGO. Academic Background 1983 - 1988 University Freiburg/Germany PhD thesis project 1979 - 1983 University Freiburg/Germany Examination as chemist (Diplomchemiker) 1976 - 1979 University Dortmund/Germany Pre examination chemistry

研究领域

Molecular nutrition related to lipid homeostasis, nutrigenomics and nutritional systems biology. Molecular mechanisms underlying genome-wide effects of foods (specific bioactive components or nutrients) on metabolic health and plasticity.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Hangelbroek, R. W., Fazelzadeh, P., Tieland, M., Boekschoten, M. V., Hooiveld, G. J., van Duynhoven, J. P., Timmons, J. A., Verdijk, L. B., de Groot, L. C., van Loon, L. J., Müller, M.(2016)Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weaknessin Journal of Cachexia, Sarcopenia and Muscle Full Text UEA Repository(Article) Cubero, F. J., Zoubek, M. E., Peng, J., Hu, W., Zhao, G., Nevzorova, Y. A., Al Masaoudi, M., Bechmann, L. P., Boekschoten, M. V., Muller, M., Preisinger, C., Gassler, N., Canbay, A. E., Luedde, T., Davis, R. J., Liedtke, C., Trautwein, C.(2016)Combined activities of JNK1 and JNK2 in hepatocytes protect against toxic liver injuryin Gastroenterology150.pp. 968-981 Full Text UEA Repository(Article) Song, S., Hooiveld, G. J., Li, M., Zhao, F., Zhang, W., Xu, X., Muller, M., Li, C., Zhou, G.(2016)Dietary soy and meat proteins induce distinct physiological and gene expression changes in ratsin Scientific Reports6. Full Text UEA Repository(Article) Fazelzadeh, P., Hangelbroek, R. W. J., Tieland, M., de Groot, L. C., Verdijk, L. B., van Loon, L. J. C., Smilde, A. K., Alves, R. D. A. M., Vervoort, J., Muller, M., van Duynhoven, J. P. M., Boekschoten, M. V.(2016)The muscle metabolome differs between healthy and frail older adultsin Journal of Proteome Research15.pp. 499-509 Full Text UEA Repository(Article) Song, S., Hooiveld, G. J., Li, M., Zhao, F., Zhang, W., Xu, X., Muller, M., Li, C., Zhou, G.(2016)Distinct physiological, plasma amino acid, and liver transcriptome responses to purified dietary beef, chicken, fish, and pork proteins in young ratsin Molecular Nutrition & Food Research60.pp. 1199-1205 Full Text UEA Repository(Article) Nyima, T., Muller, M., Hooiveld, G. J., Morine, M. J., Scotti, M.(2016)Nonlinear transcriptomic response to dietary fat intake in the small intestine of C57BL/6J micein BMC Genomics17. Full Text UEA Repository(Article) Matualatupauw, J. C., Radonjic, M., van de Rest, O., de Groot, L., Geleijnse, J., Müller, M., Afman, L.(2016)Apolipoprotein E genotype status affects habitual human blood mononuclear cell gene expression and its response to fish oil interventionin Molecular Nutrition & Food Research60.pp. 1649-1660 Full Text UEA Repository(Article) Steegenga, W. T., Mischke, M., Lute, C., Boekschoten, M. V., Lendvai, A., Pruis, M. G., Verkade, H. J., van de Heijning, B. J., Boekhorst, J., Timmerman, H. M., Plösch, T., Muller, M., Hooiveld, G. J.(2016)Maternal exposure to a Western-style diet causes differences in intestinal microbiota composition and gene expression of suckling mouse pupsin Molecular Nutrition & Food Research Full Text UEA Repository(Article) Strong, R., Miller, R. A., Antebi, A., Astle, C. M., Bogue, M., Denzel, M. S., Fernandez, E., Flurkey, K., Hamilton, K. L., Lamming, D. W., Javors, M. A., Pedro de Magalhães, J., Marinez, P. A., McCord, J. M., Miller, B. F., Muller, M., Nelson, J. F., Ndukum, J., Rainger, G. E., Richardson, A., Sabatini, D. M., Salmon, A. B., Simpkins, J. W., Steegenga, W. T., Nadon, N. L., Harrison, D. E.(2016)Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducerin Aging Cell15.pp. 872–884 Full Text UEA Repository(Article) Rusli, F., Deelen, J., Andriyani, E., Boekschoten, M. V., Lute, C., van den Akker, E. B., Muller, M., Beekman, M., Steegenga, W. T.(2016)Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J micein Scientific Reports6. Full Text UEA Repository(Article) Van Bussel, I. P. G., Jolink-Stoppelenburg, A., De Groot, C. P. G. M., Müller, M. R., Afman, L. A.(2016)Differences in genome-wide gene expression response in peripheral blood mononuclear cells between young and old men upon caloric restrictionin Genes & Nutrition11. Full Text UEA Repository(Article) Pedro de Magalhães, J., Muller, M., Rainger, G. E., Steegenga, W.(2016)Fish oil supplements, longevity and agingin Aging8.pp. 1578-1582 Full Text UEA Repository(Article) Cubero, F. J., Zhao, G., Nevzorova, Y. A., Hatting, M., Masaoudi, M. A., Verdier, J., Peng, J., Schaefer, F. M., Hermanns, N., Boekschoten, M. V., Grouls, C., Gassler, N., Kiessling, F., Muller, M., Davis, R. J., Liedtke, C., Trautwein, C.(2015)Hematopoietic cells-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injuryin Journal of Hepatology62.pp. 140-149 Full Text UEA Repository(Article) Rusli, F., Boekschoten, M. V., Zubia, A. A., Lute, C., Müller, M., Steegenga, W. T.(2015)A weekly alternating diet between caloric restriction and medium fat protects the liver from fatty liver development in middle-aged C57BL/6J micein Molecular Nutrition & Food Research59.pp. 533–543 Full Text UEA Repository(Article) Hemmerling, J., Jansen, J., Müller, M., Haller, D.(2015)Fetal gut laser microdissection in combination with RNA preamplification enables epithelial-specific transcriptional profilingin Journal of Immunological Methods416.pp. 189–192 Full Text UEA Repository(Article) Haksier, E., Boekschoten, M. V., Hu, W., Haybaeck, J., Gassler, N., Muller, M., Liedtke, C., Trautwein, C.(2015)p21 ablation in liver enhances DNA damage, cholestasis and carcinogenesisin Cancer Research75. Full Text UEA Repository(Article) van Norren, K., Rusli, F., van Dijk, M., Lute, C., Nagel, J., Dijk, F., Boekschoten, M., Luiking, Y., Witkamp, R. F., Muller, M., Steegenga, W. T.(2015)Behavioural changes are a major contributing factor in the reduction of sarcopenia in calorie-restricted ageing micein Journal of Cachexia, Sarcopenia and Muscle6.pp. 253–268 Full Text UEA Repository(Article) Gruber, L., Hemmerling, J., Schuppel, V., Muller, M., Boekschoten, M. V., Haller, D.(2015)Maternal high-fat diet accelerates development of CD-like ileitis in TNF-ARE/WT offspring without affecting fetal epithelial gene expressionin Inflammatory Bowel Diseases21.pp. 2016-2025 Full Text UEA Repository(Article) Esser, D., van Dijk, S., Oosterink, E., Lopez, S., Muller, M., Afman, L.(2015)High fat challenges with different fatty acids affect distinct atherogenic gene expression pathways in immune cells from lean and obese subjectsin Molecular Nutrition & Food Research59.pp. 1563–1572 Full Text UEA Repository(Article) Lange, K., Hugenholtz, F., Jonathan, M., Schols, H., Kleerebezem, M., Smidt, H., Muller, M., Hooiveld, G.(2015)Comparison of the effects of five dietary fibres on mucosal transcriptional profiles and luminal microbiota composition and SCFA concentrations in murine colonin Molecular Nutrition & Food Research59.pp. 1590-1602 Full Text UEA Repository(Article)