Fraser, William - University of East Anglia

个人简介

Biography Professor Bill Fraser was born and educated in Glasgow, graduating from Glasgow University with BSc (Hons) MBChB and MD (Hons). He trained in Glasgow’s teaching hospitals before spending time as a consultant/travelling fellow in Canada. Career History Bill Fraser supervises a very active research group investigating the diagnosis and treatment of metabolic bone disease including osteoporosis and Paget’s Disease of bone. He is on the Editorial Board of several journals, a Director of the Supra Regional Assay Service for bone metabolism and calcium homeostasis, and a Medical Advisor to the National Osteoporosis Society. He was a recent recipient of the ACB Foundation Award and presenter of the John Ireland Lecture. Royal Liverpool University Hospital 1991 appointed Senior Lecturer in Chemical Pathology and Head of the Metabolic Bone Disease Unit 1998 promoted to Reader 2001 Professor 2008 Head of the Unit of Clinical Chemistry August 2008 appointed Director of the Masters in Research for Clinical Science 2010 Head of Department of Musculoskeletal Biology Norwich Medical School, University of East Anglia May 2011 Professor of Medicine

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He, C., Fraser, W., Tang, J., Brown, K., Renwick, S., Rudland-Thomas, J., Teah, J., Tanqueray, E., Gleeson, M.(2016)The effect of 14 weeks of vitamin D3 supplementation on antimicrobial peptides and proteins in athletesin Journal of Sports Sciences34.pp. 67-74 Full Text UEA Repository Gregson, C. L., Wheeler, L., Hardcastle, S. A., Appleton, L. H., Addison, K. A., Brugmans, M., Clark, G. R., Ward, K. A., Paggiosi, M., Stone, M., Thomas, J., Agarwal, R., Poole, K., McCloskey, E., Fraser, W. D., Williams, E., Bullock, A. N., Smith, G. D., Brown, M. A., Tobias, J. H., Duncan, E. L.(2016)Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass casesin Journal of Bone and Mineral Research31.pp. 640-649 Full Text UEA Repository Fraser, W., Varley, I., Greeves, J., Sale, C., Friedman, E., Moran, D., Yanovich, R., Wilson, P. J., Gartland, A., Hughes, D. C., Stellingwerff, T., Ranson, C., Gallagher, J. A.(2016)Functional Polymorphisms in the P2X7 Receptor Gene are Associated with Stress Fracture Injuryin Purinergic Signalling12.pp. 103-113 Full Text UEA Repository Piec, I., Washbourne, C., Tang, J., Fisher, E., Greeves, J., Jackson, S., Fraser, W. D.(2016)How Accurate is Your Sclerostin Measurement?: Comparison Between Three Commercially Available Sclerostin ELISA Kitsin Calcified Tissue International98.pp. 546-555 Full Text UEA Repository Izard, R. M., Fraser, W. D., Negus, C., Sale, C., Greeves, J. P.(2016)Increased density and periosteal expansion of the tibia in young adult men following short-term arduous trainingin Bone88.pp. 13-19 Full Text UEA Repository Green, D., Fraser, W., Dalmay, T.(2016)Transfer RNA-derived small RNAs in the cancer transcriptomein Pflugers Archive468.pp. 1041–1047 Full Text UEA Repository Townsend, R., Elliott-Sale, K. J., Pinto, A. J., Thomas, C., Scott, J. P., Currell, K., Fraser, W. D., Sale, C.(2016)Parathyroid Hormone Secretion Is Controlled by Both Ionized Calcium and Phosphate During Exercise and Recovery in Menin The Journal of Clinical Endocrinology and Metabolism101.pp. 3231-3239 Full Text UEA Repository Piec, I., Chipchase, A., Nicholls, H., Washbourne, C., Tang, J., Fraser, W. D.(2016)Chronic kidney disease bone disease(Poster)Berry, D. J., Dutton, J., Fraser, W. D., Järvelin, M., Hyppönen, E.(2016)Harmonization Study Between LC-MS/MS and Diasorin RIA for Measurement of 25-Hydroxyvitamin D Concentrations in a Large Population Surveyin Journal of Clinical Laboratory Analysis Full Text UEA Repository Parekh, D., Patel, J. M., Scott, A., Lax, S., Dancer, R. C. A., D’Souza, V., Greenwood, H., Fraser, W. D., Gao, F., Sapey, E., Perkins, G. D., Thickett, D. R.(2016)Vitamin D Deficiency in Human and Murine Sepsisin Critical Care Medicine Full Text UEA Repository Impey, S. G., Smith, D., Robinson, A., Owens, D., Bartlett, J., Smith, K., Limb, M., Tang, J., Fraser, W., Close, G., Morton, J. P.(2015)Leucine-enriched protein feeding does not impair exercise-induced free fatty acid availability and lipid oxidation: beneficial implications for training in carbohydrate-restricted states Full Text UEA Repository(Paper)Francis, R. M., Aspray, T. J., Bowring, C. E., Fraser, W. D., Gittoes, N. J., Javaid, M. K., Macdonald, H. M., Patel, S., Selby, P. L., Tanna, N.(2015)National Osteoporosis Society practical clinical guideline on vitamin D and bone healthin Maturitas80.pp. 119-121 Full Text UEA Repository Varley, I., Hughes, D. C., Greeves, J. P., Stellingwerff, T., Ranson, C., Fraser, W. D., Sale, C.(2015)RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletesin Bone71.pp. 131-136 Full Text UEA Repository Owens, D. J., Fraser, W. D., Close, G. L., 1, 25-dihydroxyvitamin-D(2015)Vitamin D and the athlete: emerging insightsin European Journal of Sport Science15.pp. 73-84 Full Text UEA Repository Gilbert, R., Bonilla, C., Metcalfe, C., Lewis, S., Evans, D. M., Fraser, W. D., Kemp, J. P., Donovan, J. L., Hamdy, F. C., Neal, D. E., Lane, J. A., Smith, G. D., Lathrop, M., Martin, R. M., 1, 25-dihydroxyvitamin-D(2015)Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: a nested case-control studyin Cancer Causes & Control26.pp. 205-18 Full Text UEA Repository Impey, S. G., Smith, D., Robinson, A. L., Owens, D. J., Bartlett, J. D., Smith, K., Limb, M., Tang, J., Fraser, W. D., Close, G. L., Morton, J. P.(2015)Leucine-enriched protein feeding does not impair exercise-induced free fatty acid availability and lipid oxidation: beneficial implications for training in carbohydrate-restricted statesin Amino Acids47.pp. 407-416 Full Text UEA Repository Green, D., Dalmay, T., Fraser, W.(2015)Paget's disease of bone-associated osteosarcoma: molecular basis, signs and symptoms, treatment and research(Letter)Real, A., Gilbert, N., Hauser, B., Kennedy, N., Shand, A., Gillett, H., Gillett, P., Goddard, C., Cebolla, Á., Sousa, C., Fraser, W., Satsangi, J., Ralston, S., Riches, P.(2015)Characterisation of osteoprotegerin autoantibodies in coeliac diseasein Calcified Tissue International97.pp. 125-133 Full Text UEA Repository Hannan, F. M., Walls, G. V., Babinsky, V. N., Nesbit, M. A., Kallay, E., Hough, T. A., Fraser, W. D., Cox, R. D., Hu, J., Spiegel, A. M., Thakker, R. V.(2015)The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing-receptor (CaSR) mutation: relevance to autosomal dominant hypocalcemia type 1 (ADH1)in Endocrinology156.pp. en20151269 Full Text UEA Repository Dancer, R. C. A., Parekh, D., Lax, S., D'Souza, V., Zheng, S., Bassford, C. R., Park, D., Bartis, D. G., Mahida, R., Turner, A. M., Sapey, E., Wei, W., Naidu, B., Stewart, P. M., Fraser, W. D., Christopher, K. B., Cooper, M. S., Gao, F., Sansom, D. M., Martineau, A. R., Perkins, G. D., Thickett, D. R.(2015)Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS)in Thorax70.pp. 617-24 Full Text UEA Repository