SNAPE, TIM - University of Central Lancashire - School of Pharmacy and Biomedical Sciences

个人简介

After graduating from the University of Nottingham in 2000 with an MSci (Hons) in Chemistry, Tim moved to the University of Liverpool to study for a Ph.D. under the guidance of Professor Stan Roberts, studying “The Synthesis and Biological Evaluation of Cyclopentenone Prostanoids”. Following on from this, Tim spent a brief spell with a contract chemical research company in Manchester (Ultrafine Ltd) before returning to academia and a postdoctoral position under the supervision of Professor Jonathan Clayden at the University of Manchester. Having completed his postdoctoral studies in 2006, Tim took up a Research Fellow position within the Centre of Excellence for Biocatalysis, Biotransformations and Biocatalytic Manufacture (CoEBio3) within the School of Chemistry, also at the University of Manchester.

近期论文

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Chiral 1,1-diaryl compounds as important pharmacophores: Dana M. Hamad Ameen and Timothy J. Snape,* Med. Chem. Commun., 2013, 4 (6), 893 - 907. Synthetic oligoureas of metaphenylenediamine mimic host defence peptides in their antimicrobial behaviour: Sarah R. Dennison, David A. Phoenix, and Timothy J. Snape,* Bioorg. Med. Chem. Lett., 2013, 23, 9, 2518–2521. Anionic antimicrobial and anticancer peptides from plants: Saurabh Prabhu, Sarah R. Dennison, Bob Lea, Timothy J. Snape, Iain D. Nicholl, Iza Radek and Frederick Harris, Crit. Rev. Plant Sci., 2013, 32, 303–320. Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma: Saurabh Prabhu, Zaheer Akbar, Frederick Harris, Katherine Karakoula, Robert Lea, Farzana Rowther, Tracy Warr and Timothy Snape,* Bioorg. Med. Chem., 2013, 21, 1918-1924.