Cameron, Neil - Monash University - Department of Materials Science and Engineering

研究领域

Our research interests lie at the interface between materials chemistry and biology. We use modern synthetic chemistry to create designed macromolecules and materials that interrogate, interrupt or mimic biological systems and processes. This in turn leads to opportunities to create novel systems with therapeutic or biotechnological applications. Research projects fall into one or more of the following interlinked themes., New Tools for Biology: scaffolds for 3D cell culture; glycopolymers; polypeptides, New Tools for Chemistry: supported catalysts, organocatalysts, biocatalysts and, reagents; novel materials; new mass spectrometry methods for polymer sequencing, Materials for Medicine: tissue engineering; regenerative medicine; nanomedicine;, targeted delivery, Synthetic Biology: polymersomes as protocells, Current work in the group is exploring i) polypeptide nanoparticles and nanocapsules for drug delivery to the posterior segment of the eye; ii) glycosylated giant polymersomes as protocells; iii) emulsion templated and electrospun porous scaffolds as 3D cell culture substrates; iv) biodegradable emulsion templated scaffolds for the regeneration of ligaments and tendons; v) surface chemical functionalisation of porous materials to allow attachment of molecules of interest; vi) self-assembling nanostructures from biocompatible polypeptide block copolymers; vii) the application of novel mass spectrometry methods to polymer sequencing; viii) chemical functionalisation of cellulose; ix) network polymers of enhanced chemical resistance

近期论文

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V. Dao, N.R. Cameron, K. Saito, "Synthesis, properties and performance of novel organic polymers employed in flocculation applications", Polym. Chem., 7, 11-25 (2016). D.E. Mitchell, N.R. Cameron, M.I. Gibson, "Rational, yet simple, design and synthesis of an antifreeze-protein inspired polymer for cellular cryopreservation", Chem. Commun., 51, 12977-12980 (2015). D.W. Johnson, C.R. Langford, M.P. Didsbury, B. Lipp, S.A. Przyborski, N.R. Cameron, "Fully Biodegradable and Biocompatible Emulsion Templated Polymer Scaffolds by Thiol-Acrylate Polymerization of Polycaprolactone Macromonomers", Polym. Chem., 6, 7256-7263 (2015). Andres-Guerrero, M. Zong, E. Ramsay, B. Rojas, S. Sarkhel, B. Gallego, R. de Hoz, A.I. Ramirez, J.J. Salazar, A. Trivino, J.M. Ramirez, N. Cameron, B. de-las-Heras, A. Urtti, G. Mihov, A. Dias, R. Herrero-Vanrell "Novel Biodegradable Polyesteramide Microspheres for Controlled Drug Delivery in Ophthalmology", J. Contr. Rel., 211, 105-117 (2015). C.R. Langford, D.W. Johnson, N.R. Cameron, "Preparation of Hybrid Thiol-Acrylate Emulsion-templated Porous Polymers by Interfacial Co-Polymerization of High Internal Phase Emulsions", Macromol. Rapid Commun., 36, 834-839 (2015). F. Joubert, O. Musa, D.R.W. Hodgson, N.R. Cameron, "Graft copolymers of hydroxyethyl cellulose by a grafting to method: 15N labelling as a powerful characterisation tool in click polymer chemistry", Polym. Chem., 6, 1567-1575 (2015). F. Lapierre, N.R. Cameron, Y. Zhu, "Ready... set, flow: simple fabrication of microdroplet generators and their use in the synthesis of PolyHIPE microspheres", J. Micromech. Microeng. 25, 035011 (2015). T. Stukenkemper, A. Dose, M. Caballo Gonzalez, A.J.J. Groenen, S. Hehir, V. Andres-Guerrero, R. Herrero Vanrell, N.R. Cameron, "Block Copolypeptide Nanoparticles for the Delivery of Ocular Therapeutics", Macromol. Biosci., 15, 138-145 (2015). F. Joubert, G.J. Sharples, O.M. Musa, D.R.W. Hodgson, N.R. Cameron, "Preparation, properties and anti-bacterial behaviour of a novel cellulose derivative containing lactam groups", J. Polym. Sci. Pt. A: Polym. Chem., 53, 68-78 (2015). A.S. Hayward, N.R. Cameron, S.A. Przyborski, "Biointerfaces Between Cells and Substrates in Three Dimensions (3D)", in: "Biointerfaces: where material meets biology", D.W. Hutmacher and W. Chrzanowski (Eds.), Royal Society of Chemistry, Cambridge, 2015.