Williams, Spencer - University of Melbourne

研究领域

Carbohydrate chemistry and biochemistry (carbohydrate chemistry; chemical biology) Glycolipid immunology (glycoimmunology; organic chemistry) Total synthesis of bioactive natural products (organic chemistry; reaction development)

近期论文

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Erratum: Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases - Key enzymes in bacterial and fungal mannoprotein metabolism (Angewandte Chemie - International Edition (2015) 54 (5378-5382) DOI: 10.1002/anie.201410502). Angewandte Chemie - International Edition. 55. 2016 Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from: Lactobacillus plantarum and identification of its ability to signal through Mincle. Chemical Communications. 52. 2016 Chronic Brain Inflammation: The Neurochemical Basis for Drugs to Reduce Inflammation. Neurochemical Research. 41. 2016 Investigation of benzoyloximes as benzoylating reagents: benzoyl-Oxyma as a selective benzoylating reagent. Organic & Biomolecular Chemistry. 14. 2016 Corrigendum: Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 520. 2015 A Single Glycosidase Harnesses Different Pyranoside Ring Transition State Conformations for Hydrolysis of Mannosides and Glucosides 2015 Antigen Specificity of Type I NKT Cells Is Governed by TCR beta-Chain Diversity. Journal of Immunology. 195. 2015 Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle. Chemical Communications. 51. 2015 Evidence for a Boat Conformation at the Transition State of GH76 alpha-1,6-Mannanases-Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism. Angewandte Chemie - International Edition. 54. 2015 Formation of sugar radical cations from collision-induced dissociation of non-covalent complexes with S-nitroso thiyl radical precursors. International Journal of Mass Spectrometry. 378. 2015 Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 517. 2015 Mycobacterium tuberculosis beta-gentiobiosyl diacylglycerides signal through the pattern recognition receptor Mincle: total synthesis and structure activity relationships. Chemical Communications. 51. 2015 Structural and Kinetic Dissection of the endo-alpha-1,2-Mannanase Activity of Bacterial GH99 Glycoside Hydrolases from Bacteroides spp.. Chemistry - A European Journal. 21. 2015 The carbohydrate-binding promiscuity of Euonymus europaeus lectin is predicted to involve a single binding site. Glycobiology. 25. 2015