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个人简介

2020.07-至今:中国农业大学,营养与健康系,副教授 2019.04-2020.07:华盛顿州立大学,博士后 2016.03-2019.03:中国农业大学,北京食品营养与人类健康高精尖创新中心,岗位科学家 2013.07-2016.02:国家粮食局科学研究院,助理研究员、副研究员 2008.09-2013.06:中国农业大学,工学博士 2004.09-2008.06:天津大学,工学学士

研究领域

免疫与代谢 功能因子挖掘(重点糖脂代谢、肠道健康) 危害因子的内分泌干扰效应

近期论文

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Bing Fang#, Yixuan Li#, Fazheng Ren*. Chiral nanoparticles as adjuvants for vaccines. Chem, 2022, 8: 1-3. Guo-ping Zhao, Jin-wang Li, Fang-wei Yang, Xue-feng Yin, Fa-zheng Ren, Bing Fang*, Guo-fang Pang*. Spermiogenesis toxicity of imidacloprid in rats, possible role of CYP3A4. Chemosphere, 2021, 282: 131120. Fang-Wei Yang, Bing Fang*, Guo-Fang Pang, Ming Zhang, Fa-Zheng Ren. Triazophos and its metabolite diethyl phosphate have different effects on endocrine hormones and gut health in rats. Journal of Environmental Science and Health Part B, 2021, 56(6): 1-11. 杨志轩, 方冰*, 任发政, 冷小京. 牛α-乳白蛋白-油酸复合物对肿瘤细胞能量代谢的影响. 中国食品学报, 2021, 21(1): 38-43. Bing Fang*, Zhi-xuan Yang, Fa-zheng Ren. The self-assembled α-lactalbumin-oleic acid complex inhibits ATP supply from both glycolysis and the TCA cycle in HepG2 cells and HepG2-bearing nude mice. International Journal of Biological Macromolecules, 2020, 159: 258-263. Sun, Y., Yang, Z., Ren, F.Z., Fang, B*. FGF19 alleviates palmitate-induced atrophy in C2C12 cells by inhibiting mitochondrial overload and insulin resistance. International Journal of Biological Macromolecules, 2020, 158: 401-407. Sun, Y., Huang, J., Chen, Z., Du, M., Ren, F.Z., Luo, J.*, Fang, B*. Amyotrophy induced by a high-fat diet is closely related to inflammation and protein degradation determined by quantitative phosphoproteomic analysis in skeletal muscle of C57BL/6J mice. The Journal of Nutrition, 2020, 150(2), 294-302. 方冰*, 董立杰, 任发政, 周晓娟, 葛绍阳. 益生菌骆驼乳粉对II型糖尿病患者的辅助降糖作用. 中国乳品工业, 2020, 48(6): 14-17. Li, J.W., Fang, B.*, Pang, G.F., Zhang, M., Ren, F.Z. Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. Pesticide Biochemistry and Physiology, 2019, 59, 68-79. Yang, F.W., Fang, B.*, Pang, G.F., Ren, F.Z. Organophosphorus pesticide triazophos: a new endocrine disruptor chemical of hypothalamus-pituitary- adrenal axis. Pesticide Biochemistry and Physiology, 2019, 59, 91-97. Li, J.W., Pang, G.F., Ren, F.Z., Fang, B*. Chlorpyrifos-induced reproductive toxicity in rats could be partly relieved under high-fat diet. Chemosphere, 2019, 229, 94-102. Xing, H.Z., Fang, B.*, Pang, G.F., Ren, F.Z. 3-Monochloropropane-1, 2-diol causes irreversible damage to reproductive ability independent of hormone changes in adult male rats. Food and Chemical Toxicology, 2019, 124, 10-16. 方冰, 张昊, 郭慧媛, 任发政*. 毛细管区带电泳在牛乳蛋白掺假检测中的应用及方法优化. 中国食品学报, 2019, 19(3): 289-298 (EI). Fang, B.*, Li, J.W., Zhang, M., Ren, F.Z., Pang, G.F*. Chronic chlorpyrifos exposure elicits diet-specific effects on metabolism and the gut microbiome in rats. Food and Chemical Toxicology, 2018, 111, 144-152. Yang, F.W., Li, J.W., Pang, G.F., Ren, F.Z., Fang, B*. Effects of diethyl phosphate, a non-specific metabolite of organophosphorus pesticides, on serum lipid, hormones, inflammation, and gut microbiota. Molecules, 2019, 24, 2003. Fang, B.*, Zhang, M., Shan, G.K., Xing, H.Z., Ren, F.Z. α-Lactalbumin-oleic acid complex kills tumor cells by inducing excess energy metabolism but inhibiting mRNA expression of the related enzymes. Journal of Dairy Science, 2018, 101(6), 4853-4863. Fang, B.*, Zhang, M., Wu, H., Fan, X., Ren, F.Z. Internalization properties of the anti-tumor α-lactalbumin-oleic acid complex. International Journal of Biological Macromolecule, 2017, 96, 44-51. Fang, B.*, Zhang, M., Shen, Y.M. Importance of the higher retention of tocopherols and sterols for the oxidative stability of soybean and rapeseed oils. Journal of Food Science and Technology, 2017, 54(7), 1938-1944. 方冰*, 王瑛瑶, 周晓丹, 任发政. 以秀丽隐杆线虫评价植物油膳食对机体寿命的影响. 中国食品学报, 2017, 17(6), 225-231 (EI). 方冰, 栾霞, 李晓宁, 王莹辉. 利用主成分回归分析法建立微量成分与菜籽油烟点间的预测方程. 中国粮油学报, 2017, 32(4), 127-132. Fang, B.*, Zhang, M., Fan, X., Ren, F.Z. The targeted proteins in tumor cells treated with the α-lactalbumin-oleic acid complex examined by descriptive and quantitative liquid chromatography-tandem mass spectrometry. Journal of Dairy Science, 2016, 99(8), 5991-6004. Fang, B.*, Zhang, M., Ren, F.Z., Zhou, X.D. Lifelong diet including common unsaturated fatty acids extends the lifespan and affects oxidation in Caenorhabditis elegans consistently with hormesis model European Journal of Lipid Science and Technology, 2016, 118(7), 1084-1092. Wu, Y., Fang, B.*, Wu, H., Zhang, M., Shen, Y. Establishment of mathematical relationships between smoke point and minor compounds in vegetable oils using principal component regression analysis. Chemical Engineering transactions, 2016, 51, 1153-1158 (EI). 方冰, 王瑛瑶, 栾霞, 王莹辉, 朱宁科, 杨宁. 生育酚及甾醇含量对大豆油氧化稳定性及贮藏稳定性的影响. 中国粮油学报, 2016, 31(11), 69-73. 方冰, 朱宁科, 王瑛瑶, 栾霞. 大豆油和菜籽油中游离脂肪酸与烟点的数学关系研究. 中国粮油学报, 2016, 31(10), 56-59. Fang, B., Zhang, M., Tian, M., Ren, F.Z*. Self-assembled β-lactoglobulin–oleic acid and β-lactoglobulin–linoleic acid complexes with anti-tumor activities. Journal of Dairy Science, 2015, 98(5), 2898-2907. Fang, B., Zhang, M., Tian, M., Jiang, L., Ren, F.Z*. Bovine lactoferrin binds oleic acid to form an anti-tumor complex similar to HAMLET. Biochimica et Biophysica Acta- Molecular and Cell Biology of Lipids, 2014, 1841(4), 535-543. Fang, B., Guo, H.Y., Zhang, M., Jiang, L., Ren, F.Z*. The six amino acid antimicrobial peptide bLFcin6 penetrates cells and delivers siRNA. FEBS Journal, 2013, 280(4), 1007-1017. Fang, B., Jiang, L., Zhang, M., Ren, F.Z*. A novel cell-penetrating peptide TAT-A1 delivers siRNA into tumor cells selectively. Biochimie, 2013, 95(2), 251-257. Fang, B., Zhang, M., Jiang, L., Jing, H., Ren, F.Z*. Influence of pH on the structure and oleic acid binding ability of bovine α-lactalbumin. Protein Journal, 2012, 31, 564-572. Fang, B., Jiang, L., Ren, F.Z*. Effects of initial heating temperature on the crystallization rate of trans-free palm oil. Journal of Thermal Analysis and Calorimetry, 2010, 100(3), 1085-1090.

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