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个人简介

教育背景: 1999.8 ~ 2004.6 硕、博连读,博士,北京大学医学部 1991.8-~ 1996.6 学士,首都医科大学 研究经历: 2015.3-~至今 中国医学科学院药物研究所、北京协和医学院 研究员 博士生导师 2013.2~2015.3 Assistant professor, faculty. John Wayne Cancer Institute, Los Angeles, CA 90404 (美国) 2010.8~2013.1 Medical scientist, John Wayne Cancer Institute, Los Angeles, CA 90404. (美国) 2007.10~ 2010.7 Research Associate, Department of Molecular Oncology, John Wayne Cancer Institute. Los Angeles, CA 90404. (美国) 2006.7~ 2007.10 Research Associate, Department of Neuropathology, Case Western Reserve University, Cleveland, Ohio USA. (美国) 2004.6 ~ 2006.6 博士后,中国医学科学院药物研究所 1996.8-~ 1999.8 江西省人民医院

研究领域

肿瘤的药物靶点、新药筛选、发现及药理研究

近期论文

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1. Jinhua Wang*, Ying Qu*, Partha S. Ray et al. Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signaling. Journal of Clinical Investigation. 2011;121(1):212-225. (The article was elected as highlighted article) (IF:14.689) 2. Jinhua Wang*,Partha S. Ray*, Ying Qu* et al. FOXC1 is a prognostic biomarker and is functionally necessary for maintenance of aggressive cellular features in basal-like breast cancer. Cancer Research, 2010; 70(10):1-7.(The pictures in the article were chosen as the cover of magazine) (IF:8.576) 3. Jinhua Wang, I Kuiatse , AJ Casa ,AV Lee ,X Cui. JNK, essential for anticancer therapy-induced apoptosis promotes cancer breast progession. Cancer Research, 2009; 69( suppl.):(2).January 15,2009 (IF:8.576) 4. Jinhua Wang, Ying Qu, Xiaojiang, et Cui et al. FOXC1 orchestrates basal-like breast cancer cell functions by regulating NF-KB signaling (Oncogene, 2012 Nov 8;31(45):4798-802) (IF:7.18) 5. Jinhua Wang, Sharon Hunag, Ling Takeshima et al. Acquire resistance to braf-inhibitor by increasing EGFR expression. Journal of Investigative Dermatology . 2015; 135:532–541. (IF:7.216) 6. Jinhua Wang, Wei hua Sharon Huang et al. RASSF8 Regulates Progression of Cutaneous Melanoma through Nuclear Factor-κb. (Oncotarget, 2015:6:30165-30177) (IF:6.63 ) 7. Jinhua Wang, Kelly K. Chong, Yoshitaka Nakamura et al. B7-H3 Associated with Tumor Progression and Epigenetic Regulatory Activity in Cutaneous Melanoma. Journal of Investigative Dermatology. 2013; 133(8):2050-8. ( IF:6.19) 8. Jinhua Wang, Isere Kuiatse, Adrian V. Lee et al. Sustained JNK Activity Promotes Epithelial-Mesenchymal Transition, Invasion, and Survival of Breast Cancer Cells by Regulating ERK Activation. (Molecular Cancer Research, 2010; 8(2):266-277). (The article was elected as highlighted article) (IF:4.937) 9. Jinhua Wang*, Ying Qu*, Bingya Liu, Armando Giuliano, James Barsoum, and Xiaojiang Cui. Elesclomol, counteracted by Akt survival signaling, enhances the apoptotic effect of chemotherapy drugs in breast cancer cells. (Breast Cancer Research Treatment, 2010;121(2):311-21. (IF:4.467) 10. Jinhua Wang, Weibo Ka, DaGong Sun, Weijuan Yao, ZongYao Wen , and Shu Chien.Synergistic effect of cytokines EPO, IL-3 and SCF on the proliferation, differentiation and apoptosis of erythroid progenitor cells. Clinical Hemorheology and microcirculation. Clinical Hemorheology and micro circulation. 2007; 37(4): 291-9. (IF:3.398) 11. Jinhua Wang, Weibo Ka, Zhiyu Tang et al. Rheological studies on precursor cells at different stage in mice. Clinical Hemorheology and microcirculation. 2003, 29:63-69. (IF:3.398) 12. Jinhua Wang, Weibo Ka, DaGongSun, Weijuan Yao, ZongYao Wen, Shu Chien. Biochemical and biophysical studies on the precursor cells of mouse erythrocytes at different stages. Cell Biochemistry and Biophysics .2006, 45:147-156. (the article was elected as highlighted article) (IF:2.7) 13. Jin-Hua Wang*,Qing-Shan Liu*, Jian Cui, Zhi-Hong Yang, Guan-Hua Du. A novel acute anemia model for pharmacological research in mice by compelled acute exercise. Acta Pharmacologica Sinica (2009) 30: 1643-1647. (IF:2.521) 14. Jinhua Wang, Weibo Ka, Dagong Sun et al Biophysical and biorheology studies on the precursor cells at different stages. Science in China (Series. C). 2002, 45: 421-428. (IF:1.2) 15. P.S Ray , Jinhua Wang, Ying Qu, et al. Role of FOXC1 in regulation of basal-like/triple-negative breast cancer. Journal of Clinical Oncology. 2009; 27: 562S (No 15S, Part I of II). (IF:17.255) 16. Jensen TW, Ray T, Wang Jinhua, Li X et al. Diagnosis of Basal-Like Breast Cancer Using a FOXC1-Based Assay. J Natl Cancer Inst. 2015 Jun 3;107(8). (IF:13.584) 17. Min Feng, Yi Bao, Zhimei Li, Juntao Li, Min Gong, Jinhua Wang, Dave S.B. Hoon, and Qiang Yu. RASAL2 activates RAC1 to promote triple-negative breast cancer progression. J Clin Invest. 2014;124(12):5291–5304. (IF: 13.261) 18. Shuet Theng Lee, min feng …. Jinhua Wang et al. Protein Tyrosine Phosphatase UBASH3B is Overexpressed in Triple-Negative Breast Cancer and Promotes Invasion and Metastasis. Proc Natl Acad Sci U S A 2013 Jul 2;110(27):11121-6. (IF:9.598) 19. Marzese DM, Scolyer RA,….Jinhua Wang, Kawas NP, Donovan NC, Hata K, Wilmott JS, Murali R, Buckland ME, Shivalingham B, Thompson JF, Morton DL, Kelly DF and Hoon DSB. Epigenome-wide DNA Methylation Landscape of Melanoma Progression to Brain Metastasis Reveals Aberrations on Homeobox D Cluster Associated with Prognosis. Human Molecular Genetics, 2013; 23(1): 226-38. (IF:7.541) 20. Katsuya Ohta, Hiromitsu Hoshino, Jinhua Wang, et al.MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A. Oncotarget. 2015:6(5):3211-24. (IF: 6.63)

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