个人简介

Degrees PhD, Stanford University, 1990 BS, Texas A&M University, 1984 Awards and Honors U.S. National Committee Young Observer, IUPAC General Assembly (2001, 2003) Winship Distinguished Research Professor (2002) Novartis Award in Support of Synthetic Organic Chemistry (1998) Camille Dreyfus Teacher-Scholar (1997) Eli Lilly Grantee in Organic Chemistry (1995) National Science Foundation Young Investigator Award (1995) Alfred P. Sloan Research Fellow (1995) Camille and Henry Dreyfus New Faculty Award (1992)

研究领域

Synthetic Methods and Natural Products Synthesis

Courses CHEM 522: Advanced Organic Chemistry II (grad) CHEM 222: Organic Chemistry II CHEM 729: Special Topics: Organotransition Metal Chemistry (grad) CHEM 523: Advanced Organic Chemistry III

近期论文

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"Biomimetic Synthesis via Polyepoxide Cyclizations." Frank E. McDonald, Rongbiao Tong, Jason C. Valentine, and Fernando Bravo, Pure and Applied Chemistry, 2007, 79, 281-291. link "Biomimetic Syntheses from Squalene-Like Precursors: Synthesis of Abudinol B, and Reassessment of the Structure of Muzitone." Matthew A. Boone, Rongbiao Tong, Frank E. McDonald, Sheri Lense, Rui Cao, and Kenneth I. Hardcastle, Journal of the American Chemical Society, 2010, 132, 5300-5308. link "Synthesis of 15,28-Dideoxy-15,28-didehydrothyrsenol." Mary A. Smart and Frank E. McDonald, Heterocycles, 2012, 86, 535-553. link "Stereoselectivity of electrophile-promoted oxacyclizations of 1,4-dihydroxy-5-alkenes to 3-hydroxytetrahydropyrans." Frank E. McDonald, Kento Ishida, and Jessica A. Hurtak. Tetrahedron, 2013, 69, 7746-7758. link "Iodoetherification of Conformationally Restricted Dienyl Alcohols: Unexpected Formation of Oxocenes by 8-endo-mode Oxacyclizations." Kristen L. Stoltz, Andrea-Nekane R. Alba, Frank E. McDonald, Marika B. Wieliczko, and John Bacsa, Heterocycles, 2014, 88, 1519-1526. link Acyclic and macrocyclic natural products: "Total Synthesis of the Polyene-Polyol Macrolide RK-397, Featuring Cross-Couplings of Alkynylepoxide Modules." Svetlana A. Burova and Frank E. McDonald, Journal of the American Chemical Society, 2004, 126, 2495-2500. link "Modular Synthesis of the C9-C27 Degradation Product of Aflastatin A via Alkyne-Epoxide Cross-Couplings." Omar Robles and Frank E. McDonald, Organic Letters, 2008, 10, 1811-1814. link "Total Synthesis of the Sphingolipid Biosynthesis Inhibitor, Fumonisin B1." Claney L. Pereira, Yi-Hung Chen, and Frank E. McDonald, Journal of the American Chemical Society, 2009, 131, 6066-6067. link "Convergent Synthesis of Fostriecin via Selective Alkene Couplings and Regioselective Asymmetric Dihydroxylation." Omar Robles and Frank E. McDonald, Organic Letters, 2009, 11, 5498-5501. link "Fumonisin: A Template for Methodology Development and Drug Discovery." Frank E. McDonald, Claney L. Pereira, and Yi-Hung Chen, Pure and Applied Chemistry, 2011, 83, 445-459. link "Stereo- and Regioselective Synthesis of 2-Amino-3,5-diols via Stereospecific Crotyl Transfer and Regioselective Aminohydroxylation." Frank E. McDonald and Claney L. Pereira, Synthesis, 2012, 44, 3639-3648. link Oligosaccharides: "Convergent Synthesis of Digitoxin: Stereoselective Synthesis and Glycosylation of the Digoxin Trisaccharide Glycal." Frank E. McDonald and K. Subba Reddy, Angewandte Chemie International Edition in English, 2001, 40, 3653 – 3655. link "Fischer carbene catalysis of alkynol cycloisomerization: Application to the synthesis of the altromycin B disaccharide." BonSuk Koo and Frank E. McDonald, Organic Letters, 2007, 9, 1737-1740. link "Stereo- and Regioselective Glycosylations to the Bis-C-arylglycoside of Kidamycin." ZhongBo Fei and Frank E. McDonald, Organic Letters, 2007, 9, 3547-3550. link "1,5-α-D-Mannoseptanosides, Ring-size Isomers That Are Impervious to α-Mannosidase-catalyzed Hydrolysis." Matthew A. Boone, Frank E. McDonald, Joseph Lichter, Stefan Lutz, Rui Cao, and Kenneth I. Hardcastle, Organic Letters, 2009, 11, 851-854. link "Brønsted Acid-Promoted Glycosylations of Disaccharide Glycal Substructures of the Saccharomicins." Bradley R. Balthaser and Frank E. McDonald, Organic Letters, 2009, 11, 4850-4853. link "Synthesis of Human Milk Oligosaccharides: 2′- and 3-Fucosyllactose." Claney L. Pereira and Frank E. McDonald, Heterocycles, 2012, 84, 637-655. link