丁寒锋 - 浙江大学

个人简介

2003年本科毕业于浙江大学化学系，2008年获得浙江大学博士学位，2008至2011年在新加坡科技研究局从事博士后研究和担任研究科学家。2011年8月进入浙江大学化学系工作，现为浙江大学求是特聘教授、博士生导师，浙江省化学会副理事长。国家自然科学基金委青年科学基金（A类、B类）获得者，入选国家“万人计划”。研究领域为天然产物全合成及导向天然产物的新反应方法学，在多种学术刊物上发表学术论文五十余篇。曾获得Thieme Chemistry Journals Award、ACP Lectureship Award等奖励和荣誉。

研究领域

1）导向天然产物（药物）的新合成方法学开发 2）重要活性天然产物的全合成及药物化学研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

"Asymmetric Total Syntheses of Hetidine-Type C20-Diterpenoid Alkaloids: Spirasines V and VI, Spiradine D, and the Proposed Structures of Spirafines II and III" Fengjie Yao, Yufei Wu,# Yidian Sheng (UG),# Kuan Yu, Peirong Rao, Jun Xuan,* Hanfeng Ding.* J. Am. Chem. Soc. 2025, DOI: 10.1021/jacs.5c13564. "Divergent Total Syntheses of Elisapterane and Relevant Diterpenoids Assisted by In Silico Structure Reassignment" Chun-Hui Liu,# Han Gong,# Yidian Sheng (UG), Wentao Wang, Qidong Xia,* Hanfeng Ding.* J. Am. Chem. Soc. 2025, 147, 33136-33152. "A Biomimetic Approach for Construction of an Advanced Intermediate en Route to Melicolones A and B" Tianzhe Wang,# Ziqi Jia,# Chenlong Zhu, Li Zhang,* Hanfeng Ding.* J. Org. Chem. 2025, 90, 7531-7539. "Forging the Tetracyclic Core Framework of Daphlongamine B Enabled by a Peripheral Derivation of the Aza-Angular Triquinane Strategy" Huijuanzi Rao, Bin-Bin Deng, Peijie Sun, Qidong Xia, Hanfeng Ding.* Org. Lett. 2025, 27, 1779-1785. "Recent Advances on Electrocyclic Reactions in Complex Natural Product Synthesis: An Update" Ruyi Chen, Yanlin Liu, Hanfeng Ding.* Org. Chem. Front. 2025, 12, 2415-2438. "Divergent Total Syntheses of Phragmalin and Khayanolide-Type Limonoids: A Torquoselective Interrupted Nazarov Approach" Peirong Rao, Dongmin Tang, Qidong Xia, Jialei Hu, Xufeng Lin, Jun Xuan,* Hanfeng Ding.* J. Am. Chem. Soc. 2025, 147, 3003-3009. "Advances in the Total Syntheses of Tetraquinane and Tetraquinane-type Terpenes" Yunbo Yang, Hanfeng Ding.* Chin. J. Org. Chem. 2025, 45, 725-747. "Cooperative Iodine and Nitrate Catalyzed Oxidation of Stilbenes to α-Diketones in Water" Junfei Luo,* Yue Lv, Keqi Tang, Hanfeng Ding.* Chem. Asian J. 2025, 20, e202401557. (book chapter) "[5+2] and [6+2] Cycloaddition Reaction of Alkenes, Alkynes, Allenes and 1,3-Dienes" Hanfeng Ding, Kai Gao, Yong Qu, Qidong Xia. In Comprehensive Organic Synthesis, 3rd Edition, Garry Molander, Paul Knochel., Eds., Elsevier, 2025, Vol. 5, pp. 67-189. "Bench-Stable Meisenheimer Complexes: Synthesis, Characterization, and Divergent Reactivity for Dearomatization" Wei-Long Zeng,# Qidong Xia,# Chu-Qiao Li, Ming-Yang Wang, Wang-Ye Jin, Hanfeng Ding,* Wei Li.* J. Am. Chem. Soc. 2024, 146, 30764-30770. "Five Decades of Endeavor towards Total Syntheses of Grayanane Diterpenoids" Qidong Xia, Hanfeng Ding,* Tetrahedron Lett. 2024, 145, 155160. "A Unified Synthetic Approach to the Pleurotin Natural Products" Yong Gao, Qidong Xia, An Zhu, Wenkuan Mao, Yiming Mo, Hanfeng Ding,* Jun Xuan.* J. Am. Chem. Soc. 2024, 146, 18230-18235. "Forging the Tetracyclic Core Framework of Rhodomolleins XIV and XLII: A Ring Distortion Approach" Zhen-Ning Yang,# Huijuanzi Rao,# Yuhao Yin, Shan Mu, Ziqi Jia, Hanfeng Ding.* Org. Lett. 2024, 26, 3524-3529. "Total Synthesis of (−)-Retigeranic Acid A: A Reductive Skeletal Rearrangement Strategy"Dongyu Sun,# Ruyi Chen,# Dongmin Tang,# Qidong Xia (UG), Yifan Zhao, Chun-Hui Liu, Hanfeng Ding.* J. Am. Chem. Soc. 2023, 145, 11927-11932. "A Study Travel of Sodium Nitrite" Xiang Li (UG), Taibao Wang (UG), Ping Lu, Hanfeng Ding.* Univ. Chem. 2023, 38, 32−37. "Divergent Total Syntheses of (+)-Vulgarisins A–E"Kaixiang Xu, Shan Mu, Huijuanzi Rao, Jialei Hu, Hanfeng Ding.* Angew. Chem. Int. Ed. 2023, 62, e202303668. "Divergent Synthetic Approach to Grayanane Diterpenoids"An Zhu,# Yumeng Lyu,# Qidong Xia(UG),# Yufei Wu, Dongmin Tang, Chi He, Guijuan Zheng, Yuanyuan Feng, Yong Wang, Guangming Yao,* Hanfeng Ding.* J. Am. Chem. Soc. 2023, 145, 8540-8549. "Divergent Total Syntheses of (–)-Crinipellins Facilitated by a HAT-Initiated Dowd–Beckwith Rearrangement" Yifan Zhao,# Jialei Hu,# Ruyi Chen,# Fengping Xiong (UG), Hujun Xie,* Hanfeng Ding.* J. Am. Chem. Soc. 2022, 144, 2495-2500. "Asymmetric Total Synthesis of Taxol" Dongyu Sun, Hanfeng Ding.* Chin. J. Org. Chem. 2021, 41, 4827-4829. (Highlight) "Asymmetric Total Syntheses of (+)-Davisinol and (+)-18-Benzoyldavisinol: A HAT-Initiated Transannular Redox Radical Approach" Kuan Yu,# Fengjie Yao,# Qingrui Zeng (UG), Hanfeng Ding.* J. Am. Chem. Soc. 2021, 143, 10576-10581. "Asymmetric Total Syntheses of 8,9-Seco-ent-kaurane Diterpenoids Enabled by An Electrochemical ODI-[5+2] Cascade" Bingnan Wang,# Zhaobo Liu,# Zhenzhong Tong, Beiling Gao, Hanfeng Ding.* Angew. Chem. Int. Ed. 2021, 60, 14892-14896. "Electrochemical ODI-[5+2] Cascade for the Syntheses of Diversely Functionalized Bicyclo[3.2.1]octane Frameworks" Zhaobo Liu, Jialei Hu,* Hanfeng Ding.* Org. Lett. 2021, 23, 6745-6749. "Total Synthesis of (+)-Alsmaphorazine C and Formal Synthesis of (+)-Strictamine: A Photo-Fries Approach" Beiling Gao, Fengjie Yao,# Zhaodong Zhang (UG),# Hanfeng Ding.* Angew. Chem. Int. Ed. 2021, 60, 10603-10607. "Tetracyclic Diterpenoid Synthesis Facilitated by ODI-Cascade Approaches to Bicyclo[3.2.1]octane Skeletons" Kai Gao,# Jialei Hu,# Hanfeng Ding.* Acc. Chem. Res. 2021, 54, 875-889. "Asymmetric Total Synthesis of Spirostanol Bufospirostenin A" Zhenzhong Tong, Hanfeng Ding.* Chin. J. Org. Chem. 2020, 40, 3984-3985. (Highlight) "Total Synthesis of (-)-Rhodomollanol A" Jianhong Gao,# Peirong Rao,# Kaixiang Xu, Shuaifeng Wang, Yufei Wu, Chi He, Hanfeng Ding.* J. Am. Chem. Soc. 2020, 142, 4592-4597. "Total Syntheses of (+)-Stemarin and the Proposed Structures of Stemara-13(14)-en-18-ol and Stemara-13(14)-en-17-acetoxy-18-ol" Jialei Hu, Ziqi Jia, Kaixiang Xu, Hanfeng Ding.* Org. Lett. 2020, 22, 1426-1430. "Recent Advances in the Total Synthesis of Cyclobutane-Containing Natural Products" Jinshan Li,# Kai Gao,# Ming Bian, Hanfeng Ding.* Org. Chem. Front. 2020, 7, 136-154. "Total Synthesis of (+)-Jatrophalactam" Jianhong Gao,# Dongyu Sun,# Kuan Yu, Hujun Xie, Hanfeng Ding.* Org. Lett. 2019, 21, 9603-9607. "Total Syntheses of Rhodomolleins XX and XXII: A Reductive Epoxide-Opening/Beckwith–Dowd Approach" Kuan Yu, Zhen-Ning Yang, Chun-Hui Liu, Shao-Qi Wu, Xin Hong, Xiao-Li Zhao, Hanfeng Ding.* Angew. Chem. Int. Ed. 2019, 58, 8556-8560. "Total Synthesis of (-)-Pavidolide B: A Ring Contraction Strategy" Peirong Rao, Jialei Hu, Jun Xuan, Hanfeng Ding.* J. Org. Chem. 2019, 84, 9385-9392. "Total Syntheses of (+)-Sarcophytin, (+)-Chatancin, (-)-3-Oxochatancin, and (-)-Pavidolide B: A Divergent Approach" Chuan He,# Jun Xuan,# Peirong Rao, Pei-Pei Xie, Xin Hong, Xufeng Lin,* Hanfeng Ding.* Angew. Chem. Int. Ed. 2019, 58, 5100-5104. "Recent Development on the [5+2] Cycloadditions and Their Application in Natural Product Synthesis" Kai Gao, Yong-Gang Zhang, Zhiming Wang, Hanfeng Ding.* Chem. Commun. 2019, 55, 1859-1878. "Total Synthesis of An Atropisomer of the Schisandra Triterpenoid Schiglautone A" Binjie Ma,# Yifan Zhao,# Chi He, Hanfeng Ding.* Angew. Chem. Int. Ed. 2018, 57, 15567-15571. "Diastereoselective Synthesis of the Hydroperoxide-Keto Form of (+/-)-Steenkrotin B" Jun Xuan,# An Zhu,# Binjie Ma, Hanfeng Ding.* Org. Lett. 2018, 20, 4153-4156.