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Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq
MA Matilla, FJ Leeper, GP Salmond – Environmental Microbiology (2015) n/a
(DOI: 10.1111/1462-2920.12839)
Asymmetric Stetter reactions catalyzed by thiamine diphosphate-dependent enzymes
E Kasparyan, M Richter, C Dresen, LS Walter, G Fuchs, FJ Leeper, T Wacker, SLA Andrade, G Kolter, M Pohl, M Müller – Applied Microbiology and Biotechnology (2014) 98, 9681
(DOI: 10.1007/s00253-014-5850-0)
Diazo group as a new chemical reporter for bioorthogonal labelling of biomolecules
L Josa-Culleré, YA Wainman, KM Brindle, FJ Leeper – RSC Advances (2014) 4, 52241
(DOI: 10.1039/C4RA08861A)
Specificity and promiscuity at the branch point in gentamicin biosynthesis.
J Guo, F Huang, C Huang, X Duan, X Jian, F Leeper, Z Deng, PF Leadlay, Y Sun – Chemistry & Biology (2014) 21, 608
(DOI: 10.1016/j.chembiol.2014.03.005)
Gold(i)-catalysed synthesis of a furan analogue of thiamine pyrophosphate
A Iqbal, ELH Sahraoui, FJ Leeper – Beilstein journal of organic chemistry (2014) 10, 2580
(DOI: 10.3762/bjoc.10.270)
Structure of a eukaryotic thiaminase I.
CA Kreinbring, SP Remillard, P Hubbard, HR Brodkin, FJ Leeper, D Hawksley, EY Lai, C Fulton, GA Petsko, D Ringe – Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 137
(DOI: 10.1073/pnas.1315882110)
Dual-sugar imaging using isonitrile and azido-based click chemistries
YA Wainman, AA Neves, S Stairs, H Stöckmann, H Ireland-Zecchini, KM Brindle, FJ Leeper – Org Biomol Chem (2013) 11, 7297
(DOI: 10.1039/c3ob41805g)
Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
S Lüdtke, P Neumann, KM Erixon, F Leeper, R Kluger, R Ficner, K Tittmann – Nature Chemistry (2013) 5, 762
(DOI: 10.1038/nchem.1728)
Imaging cell surface glycosylation in vivo using "double click" chemistry.
Neves, H Stöckmann, YA Wainman, JC Kuo, S Fawcett, FJ Leeper, KM Brindle – Bioconjugate Chemistry (2013) 24, 934
(DOI: 10.1021/bc300621n)
Metabolic glycan imaging by isonitrile-tetrazine click chemistry
S Stairs, AA Neves, H Stöckmann, YA Wainman, H Ireland-Zecchini, KM Brindle, FJ Leeper – ChemBioChem (2013) 14, 1063
(DOI: 10.1002/cbic.201300130)
Synthesis of 3,4-Disubstituted Pyrroles. A Review
FJ Leeper, JM Kelly – Organic Preparations and Procedures International (2013) 45, 171
(DOI: 10.1080/00304948.2013.786590)
α-Hydroxy-β-keto acid rearrangement–decarboxylation: impact on thiamine diphosphate-dependent enzymatic transformations
M Beigi, S Loschonsky, P Lehwald, V Brecht, SL Andrade, FJ Leeper, W Hummel, M Müller – Org Biomol Chem (2013) 11, 252
(DOI: 10.1039/c2ob26981c)
Bacterial Biosynthetic Gene Clusters Encoding the Anti-cancer Haterumalide Class of Molecules BIOGENESIS OF THE BROAD SPECTRUM ANTIFUNGAL AND ANTI-OOMYCETE COMPOUND, OOCYDIN A
MA Matilla, H Stöckmann, FJ Leeper, GP Salmond – J Biol Chem (2012) 287, 39125
(DOI: 10.1074/jbc.M112.401026)
Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues.
L Chen, E Cressina, N Dixon, K Erixon, K Agyei-Owusu, J Micklefield, AG Smith, C Abell, FJ Leeper – Org Biomol Chem (2012) 10, 5924
(DOI: 10.1039/c2ob07116a)
Characterisation of PigC and HapC, the prodigiosin synthetases from Serratia sp and Hahella chejuensis with potential for biocatalytic production of anticancer agents
SR Chawrai, NR Williamson, T Mahendiran, GPC Salmond, FJ Leeper – Chemical Science (2012) 3, 447
(DOI: 10.1039/c1sc00588j)
Copper-free click - A promising tool for pre-targeted PET imaging
HL Evans, RL Slade, L Carroll, G Smith, QD Nguyen, L Iddon, N Kamaly, H Stöckmann, FJ Leeper, EO Aboagye, AC Spivey – Chemical communications (Cambridge, England) (2012) 48, 991
(DOI: 10.1039/c1cc16220a)
Identification and characterisation of the gene cluster for the anti-MRSA antibiotic bottromycin: Expanding the biosynthetic diversity of ribosomal peptides
WJK Crone, FJ Leeper, AW Truman – Chemical Science (2012) 3, 3516
(DOI: 10.1039/c2sc21190d)
Synthesis of 3,4-fused cycloalkanopyrroles by 1,3-dipolar cycloaddition
JM Kelly, FJ Leeper – Tetrahedron Letters (2012) 53, 819
(DOI: 10.1016/j.tetlet.2011.12.013)
Exploring isonitrile-based click chemistry for ligation with biomolecules.
H Stöckmann, AA Neves, S Stairs, KM Brindle, FJ Leeper – Org Biomol Chem (2011) 9, 7303
(DOI: 10.1039/c1ob06424j)
(E,E)-1,5-Cyclooctadiene: A small and fast click-chemistry multitalent
H Stöckmann, AA Neves, HA Day, S Stairs, KM Brindle, FJ Leeper – Chemical communications (Cambridge, England) (2011) 47, 7203
(DOI: 10.1039/c1cc12161h)
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