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Leigh, David Professor 收藏
The University of Manchester     School of Chemistry
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个人简介

B.Sc. (1984); Ph. D. (1987) University of Sheffield 1987-89 Postdoctoral Research Associate, National Research Council of Canada (Ottawa) 1989-95 Lecturer in Organic Chemistry, University of Manchester Institute of Science and Technology 1996-98 Reader in Organic Chemistry, University of Manchester Institute of Science and Technology 1998-2001 Chair of Synthetic Chemistry, University of Warwick 1998-2003 EPSRC Advanced Research Fellow 2001-12 Forbes Chair of Organic Chemistry, University of Edinburgh 2012-13 Professor of Organic Chemistry, University of Manchester 2014- Sir Samuel Hall Chair of Chemistry, University of Manchester 2003 Royal Society of Chemistry Award for Supramolecular Chemistry 2004 Fellow of the Royal Society of Chemistry 2004 Royal Society of Chemistry Interdisciplinary Award 2005 Institute of Chemistry of Ireland Award for Chemistry 2005 Swiss Chemical Society Troisième Conferencier in Chemistry 2005 Elected Fellow of the Royal Society of Edinburgh, Scotland’s National Academy of Science & Letters 2005 Royal Society-Wolfson Research Merit Award 2005-10 EPSRC Senior Research Fellow 2005 Royal Society of Chemistry Award for Nanotechnology 2007 International Izatt-Christensen Award in Macrocyclic Chemistry 2007 Royal Society of Chemistry-Real Sociedad Española de Química (RSC-RSEQ) Prize for Chemistry 2007 Chancellor's Award for Research 2007 Feynman Prize for Nanotechnology 2007 Descartes Prize for Research 2008 ERC Advanced Grant (inaugural call) 2009 Elected Fellow of the Royal Society (London), the National Academy of Science of the UK and the Commonwealth 2009 Royal Society of Chemistry Merck Award 2010 Royal Society of Chemistry Tilden Prize 2013 Royal Society Bakerian Lecture 2014 Royal Society of Chemistry Pedler Award 2015 Elected to the Academia Europaea, the European Academy of Science, Humanities & Letters 2016-26 Royal Society Research Professor 2017 Royal Society of Chemistry Perkin Prize for Organic Chemistry Member of the American Chemical Society, the American Association for the Advancement of Science and the Manchester Circle of Magicians. Fellow of the Royal Society of Chemistry, the Royal Society of Edinburgh and the Royal Society (London). Associate Editor of Chemical Science. Member of the International Advisory Board of Angewandte Chemie. Member of the Editorial Advisory Board of ACS Central Science. Member of the International Guild of Knot Tyers.

研究领域

The Leigh group's research interests include the development of new strategies for interlocked molecule synthesis and the design, construction and application of artificial molecular motors and machines. CHEMICAL TOPOLOGY Developing novel strategies and methodologies for the synthesis of catenanes, rotaxanes and molecular knots. MOLECULAR MOTORS AND MACHINES The design, synthesis, characterisation and application of artificial molecular motors, molecules that can walk along tracks and functional molecular machines. MOLECULAR MACHINES FOR SYNTHESIS The design, synthesis, characterisation and application of artificial molecular machines for chemical synthesis, including switchable catalysts, molecular transporters and molecular robots that can make other molecules. SUPRAMOLECULAR POLYMERS The design, synthesis and characterisation of extremely strong hydrogen bond motifs and their incorporation into supramolecular polymers. The synthesis of complex molecular topologies as models of polymer entanglements. KEYWORDS: Organic synthesis, supramolecular chemistry, chemical topology, catalysis, supramolecular polymers, molecular motors, molecular machines, nanotechnology, advanced materials

近期论文

‘Analysis of two [2]catenanes based on electron densities from invariom refinement and results from DFT calculations’, P Luger, B Dittrich, S Mebs, A M Z Slawin and D A Leigh, Z. Naturforsch., published online 24 Sept 2018. ‘Stereoselective synthesis of a composite knot with nine crossings’, L Zhang, A J Stephens, A L Nussbaumer, J-F Lemonnier, P Jurček, I J Vitorica-Yrezabal and D A Leigh, Nature Chem, published online 10 Sept 2018. ‘A six-crossing doubly interlocked [2]catenane with twisted rings, and a molecular granny knot’, J J Danon, D A Leigh, S Pisano, A Valero and I J Vitorica-Yrezabal, Angew Chem Int Ed, published online 28 Aug 2018. ‘Comment on “Coordination-Driven Self-Assembly of a Molecular Knot Comprising Sixteen Crossings"’, D A Leigh, J-F Lemonnier and S L Woltering, Angew Chem Int Ed, 57, 12212-12214 (2018). ‘Spontaneous assembly of rotaxanes from a primary amine, crown ether and electrophile’, S D P Fielden, D A Leigh, C T McTernan, B Pérez-Saavedra and I J Vitorica-Yrezabal, J Am Chem Soc, 140, 6049-6052 (2018). ‘Securing a supramolecular architecture by tying a stopper knot’, D A Leigh, L Pirvu, F Schaufelberger, D J Tetlow and L Zhang, Angew Chem Int Ed, 57, 10484-10488 (2018). [VIP paper] Featured as the Frontispiece (image credit: Jo Richers; www.jorichers.com). ‘An artificial molecular machine that builds an asymmetric catalyst’, G De Bo, M A Y Gall, S Kuschel, J De Winter, P Gerbaux and D A Leigh, Nature Nanotech, 13, 381-385 (2018). ‘A molecular trefoil knot from a trimeric circular helicate’, L Zhang, D P August, J Zhong, G F S Whitehead, I J Vitorica-Yrezabal and D A Leigh, J Am Chem Soc, 140, 4982-4985 (2018). ‘Molecular machines with bio-inspired mechanisms’, L Zhang, V Marcos and D A Leigh, Proc Natl Acad Sci USA, 115, 9397-9404 (2018).

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