B.Sc. (1984); Ph. D. (1987) University of Sheffield
1987-89 Postdoctoral Research Associate, National Research Council of Canada (Ottawa)
1989-95 Lecturer in Organic Chemistry, University of Manchester Institute of Science and Technology
1996-98 Reader in Organic Chemistry, University of Manchester Institute of Science and Technology
1998-2001 Chair of Synthetic Chemistry, University of Warwick
1998-2003 EPSRC Advanced Research Fellow
2001-12 Forbes Chair of Organic Chemistry, University of Edinburgh
2012-13 Professor of Organic Chemistry, University of Manchester
2014- Sir Samuel Hall Chair of Chemistry, University of Manchester
2003 Royal Society of Chemistry Award for Supramolecular Chemistry
2004 Fellow of the Royal Society of Chemistry
2004 Royal Society of Chemistry Interdisciplinary Award
2005 Institute of Chemistry of Ireland Award for Chemistry
2005 Swiss Chemical Society Troisième Conferencier in Chemistry
2005 Elected Fellow of the Royal Society of Edinburgh, Scotland’s National Academy of Science & Letters
2005 Royal Society-Wolfson Research Merit Award
2005-10 EPSRC Senior Research Fellow
2005 Royal Society of Chemistry Award for Nanotechnology
2007 International Izatt-Christensen Award in Macrocyclic Chemistry
2007 Royal Society of Chemistry-Real Sociedad Española de Química (RSC-RSEQ) Prize for Chemistry
2007 Chancellor's Award for Research
2007 Feynman Prize for Nanotechnology
2007 Descartes Prize for Research
2008 ERC Advanced Grant (inaugural call)
2009 Elected Fellow of the Royal Society (London), the National Academy of Science of the UK and the Commonwealth
2009 Royal Society of Chemistry Merck Award
2010 Royal Society of Chemistry Tilden Prize
2013 Royal Society Bakerian Lecture
2014 Royal Society of Chemistry Pedler Award
2015 Elected to the Academia Europaea, the European Academy of Science, Humanities & Letters
2016-26 Royal Society Research Professor
2017 Royal Society of Chemistry Perkin Prize for Organic Chemistry
Member of the American Chemical Society, the American Association for the Advancement of Science and the Manchester Circle of Magicians. Fellow of the Royal Society of Chemistry, the Royal Society of Edinburgh and the Royal Society (London). Associate Editor of Chemical Science. Member of the International Advisory Board of Angewandte Chemie. Member of the Editorial Advisory Board of ACS Central Science. Member of the International Guild of Knot Tyers.
The Leigh group's research interests include the development of new strategies for interlocked molecule synthesis and the design, construction and application of artificial molecular motors and machines.
Developing novel strategies and methodologies for the synthesis of catenanes, rotaxanes and molecular knots.
MOLECULAR MOTORS AND MACHINES
The design, synthesis, characterisation and application of artificial molecular motors, molecules that can walk along tracks and functional molecular machines.
MOLECULAR MACHINES FOR SYNTHESIS
The design, synthesis, characterisation and application of artificial molecular machines for chemical synthesis, including switchable catalysts, molecular transporters and molecular robots that can make other molecules.
The design, synthesis and characterisation of extremely strong hydrogen bond motifs and their incorporation into supramolecular polymers. The synthesis of complex molecular topologies as models of polymer entanglements.
KEYWORDS: Organic synthesis, supramolecular chemistry, chemical topology, catalysis, supramolecular polymers, molecular motors, molecular machines, nanotechnology, advanced materials
‘Analysis of two catenanes based on electron densities from invariom refinement and results from DFT calculations’, P Luger, B Dittrich, S Mebs, A M Z Slawin and D A Leigh, Z. Naturforsch., published online 24 Sept 2018.
‘Stereoselective synthesis of a composite knot with nine crossings’, L Zhang, A J Stephens, A L Nussbaumer, J-F Lemonnier, P Jurček, I J Vitorica-Yrezabal and D A Leigh, Nature Chem, published online 10 Sept 2018.
‘A six-crossing doubly interlocked catenane with twisted rings, and a molecular granny knot’, J J Danon, D A Leigh, S Pisano, A Valero and I J Vitorica-Yrezabal, Angew Chem Int Ed, published online 28 Aug 2018.
‘Comment on “Coordination-Driven Self-Assembly of a Molecular Knot Comprising Sixteen Crossings"’, D A Leigh, J-F Lemonnier and S L Woltering, Angew Chem Int Ed, 57, 12212-12214 (2018).
‘Spontaneous assembly of rotaxanes from a primary amine, crown ether and electrophile’, S D P Fielden, D A Leigh, C T McTernan, B Pérez-Saavedra and I J Vitorica-Yrezabal, J Am Chem Soc, 140, 6049-6052 (2018).
‘Securing a supramolecular architecture by tying a stopper knot’, D A Leigh, L Pirvu, F Schaufelberger, D J Tetlow and L Zhang, Angew Chem Int Ed, 57, 10484-10488 (2018). [VIP paper] Featured as the Frontispiece (image credit: Jo Richers; www.jorichers.com).
‘An artificial molecular machine that builds an asymmetric catalyst’, G De Bo, M A Y Gall, S Kuschel, J De Winter, P Gerbaux and D A Leigh, Nature Nanotech, 13, 381-385 (2018).
‘A molecular trefoil knot from a trimeric circular helicate’, L Zhang, D P August, J Zhong, G F S Whitehead, I J Vitorica-Yrezabal and D A Leigh, J Am Chem Soc, 140, 4982-4985 (2018).
‘Molecular machines with bio-inspired mechanisms’, L Zhang, V Marcos and D A Leigh, Proc Natl Acad Sci USA, 115, 9397-9404 (2018).