个人简介
EDUCATION
1998 BS, Nanjing University, China
2004 PhD, Columbia University, USA
ACADEMIC CAREER
2015-present Professor, the State Key Laboratory of Elemento-organic Chemistry, Nankai University
2018-present Adjunct professor, The Pennsylvania State University
2014-2015 Associate Professor, Department of Chemistry, The Pennsylvania State University, USA
2008-2014 Assistant Professor, Department of Chemistry, The Pennsylvania State University, USA
2005-2008 Postdoctoral, Memorial Sloan-Kettering Cancer Center, USA
HONORS
ACP lectureship awards in Japan and Malaysia 2018
National Natural Science Fund for Distinguished Young Scholars of China 2017
WuXi AppTec Scholar Award in Life Science and Chemistry 2016
Distinguished Junior Faculty Award by Chinese-American Chemistry & Chemical Biology
Professor Association (CAPA) 2014
Amgen Young Investigator Award 2013
Thieme Chemistry Journal Award 2011
National Science Foundation (NSF) CAREER Award 2011
Penn State Clinical and Translational Science Award (CTSA) 2009
New York State Breast Cancer Research Postdoctoral Fellowship 2007
研究领域
Organometallic chemistry，synthetic methodology, total synthesis, chemical biology of complex peptides and oligosaccharides, medicinal chemistry
近期论文
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Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand. Hao Wang, Zibo Bai, Tangqian Jiao, Zhiqiang Deng, Huarong Tong, Gang He*, Qian Peng*, and Gong Chen* J. Am. Chem. Soc. 2018, asap, DOI: 10.1021/jacs.8b00641.
General Strategy for Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular sp3 C−H Arylation. Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He*, Xiangbing Qi*, Weijun Shen*, Peng Liu* and Gong Chen*. Nature Chem. 2018, accepted.
An Enantioselective Bidentate Auxiliary Directed Palladium- Catalyzed Benzylic C H Arylation of Amines Using a BINOL Phosphate Ligand. Hao Wang, Hua-Rong Tong, Gang He*, and Gong Chen*. Angew. Chem., Int. Ed. 2016, 55, 15387-15391.
Benzazetidine Synthesis via Palladium-Catalyzed Intramolecular C−H Amination. Gang He,* Gang Lu, Zhengwei Guo, Peng Liu,* and Gong Chen*. Nature Chem. 2016, 8, 1131-1136.
Total Synthesis of Mannopeptimycins and α and β. Bo Wang, Yunpeng Liu, Rui Jiao, Yiqing Feng, Qiong Li, Chen Chen, Long Liu, Gang He, and Gong Chen*. J. Am. Chem. Soc. 2016, 138, 3926-3932, DOI: 10.1021/jacs.6b01384
Pd-catalyzed Mono-selective ortho-C−H Alkylation of N-Quinolyl Benzamides: Evidence for Stereo-retentive Coupling of Secondary Alkyl Iodides. Shuyu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2015, 137, 531-539.
Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Methylene C(sp3)−H Bonds. Shu-Yu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2013, 135, 12135−12141.
Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated C(sp3)−H Bonds. Gang He, Shu-Yu Zhang, William A. Nack, and Gong Chen*. Angew. Chem., Int. Ed. 2013, 52, 11124−11128.
Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)−H Bonds with Alkyl Iodides. Shuyu Zhang, Gang He, William A. Nack, Yingsheng Zhao, Qiong Li, and Gong Chen*. J. Am. Chem. Soc. 2013, 135, 2124−2127.
Efficient Ether Synthesis via Palladium-catalyzed Picolinamide-directed Alkoxylation of Unactivated C(sp3) and C(sp2)−H Bonds at Remote Positions. Shuyu Zhang, Gang He, Yingsheng Zhao, and Gong Chen*. J. Am. Chem. Soc. 2012, 134, 7313−7316.
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