个人简介
讲师,国家高端外专项目团队核心成员,中国化学会会员,国家执业药师。2011年本科毕业于辽宁大学制药工程专业,2016年博士毕业于中国科学院大连化学物理研究所有机化学专业,2017.1-2018.12在南京工业大学药学院工作,2018年在澳洲Monash University药学院从事小分子药物合成工作,2019年1月至今,在南京师范大学食品与制药工程学院工作。发表研究论文近40篇,其中一作和通讯文章20多篇,被引频次600多次,其中高被引论文1篇。申请中国发明专利22项,授权2项。发表会议论文10多篇。主持或参与国家级或省级基金5项。
研究领域
(1) 药物化学及合成:小分子药物设计、合成及其活性筛选;开发绿色高效催化体系,高效合成具有潜在药物活性的小分子化合物。
(2) 食品化学及分析检测:食品中非法添加剂的结构鉴定及快速检测技术开发。
(3) 生物质资源化利用:研究非均相催化反应及其机理,并实现小分子药物或高附加值化学品的高效绿色合成。
(4) 药物降解分析:环境和食品中残留药物的降解过程及其机理研究
近期论文
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(1) C-Alkylation of Ketones and Related Compounds by Alcohols: Transition-Metal-Catalyzed Dehydrogenation. Angew. Chem. Int. Ed. 2016, 55, 862 (IF = 12.102, 一区,高被引论文).
(2) Ofloxacin Degradation over Cu-Ce Tyre Carbon Catalysts by the Microwave Assisted Persulfate Process. Appl. Catal. B: Environ. 2019, 253, 149 (IF = 11.698,一区).
(3) Copper-Catalyzed Formal Carbene Migratory Insertion into Internal Olefinic C═C Bonds with N-Tosylhydrazones to Access Iminofuran and 2(3H)-Furanone Derivatives. Org. Lett. 2017, 19, 3660.
(4) Copper-Mediated Intramolecular Oxidative C–H/N–H Cross-Coupling of α-Alkenoyl Ketene N,S-Acetals to Synthesize Pyrrolone Derivatives. Chem. Commun. 2014, 50, 12479.
(5) Amide Bond Formation Assisted by Vicinal Alkylthio Migration in Enaminones: Metal and CO-Free Synthesis of α,β-Unsaturated Amides. J. Org. Chem. 2018, 83, 5731.
(6) Copper-Mediated Intramolecular Oxidative C–H/C–H Cross-coupling of alpha-Oxo Ketene N,S-Acetals for Indole Synthesis. J. Org. Chem. 2014, 79, 10553.
(7) Copper-Catalyzed Trifluoromethylation of Internal Olefinic C-H Bonds: Efficient Routes to Trifluoromethylated Tetrasubstituted Olefins and N-Heterocycles. Chem. Eur. J. 2014, 20, 3439.
(8) Temperature Influence and Distribution of Bio-oil from Pyrolysis of Granular Sewage Sludge. J. Anal. Appl. Pyrol. 2018, 130, 36.
(9) Heterogeneous Fenton-like degradation of ofloxacin over sludge derived carbon as catalysts: Mechanism and performance. Sci. Total Environ. 2018, 654, 942.
(10) Determination and Toxicity Evaluation of the generated Byproducts from sulfamethazine Degradation during Catalytic Oxidation Process. Chemosphere 2019, 226, 103.
(11) New KAT6 Inhibitors Induce Senescence and Arrest Cancer Growth. Synth. Syst. Biotech. 2018, 3, 244.
(12) 3,3’-Disubstituted 5,5’-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity. J. Med. Chem. 2019, 62, 2485.