个人简介

B.Sc. 1990 Chemistry - University of Barcelona, Spain Ph.D. 1996 Organic Chemistry - University of Barcelona, Spain

研究领域

Chemical biology Protein and peptide therapeutics Microbial pathogenicity Genetically-encoded biosensors

The practical and conceptual opportunities made available by recent innovations in the emerging fields of synthetic protein chemistry and protein expression using modified protein splicing elements are providing a fertile source for innovative biotechnology tools to study the physico-chemical basis of protein function in vivo and in vitro. The Camarero Lab is focused in using these generic chemistry-driven technologies for studying biological process involved in bacterial pathogenicity and Chem-Biosensing.

近期论文

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Camarero JA - Legume cyclotides shed light on the genetic origin of knotted circular proteins. - Proc Natl Acad Sci U S A [2011] Jun 21;108(25):10025-6 PubMed Berrade L,Garcia AE,Camarero JA - Protein microarrays: novel developments and applications. - Pharm Res [2011] Jul;28(7):1480-99 PubMed Puttamadappa SS,Jagadish K,Shekhtman A,Camarero JA - Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin. - Angew Chem Int Ed Engl [2010] Sep 17;49(39):7030-4 PubMed Garcia AE,Camarero JA - Biological activities of natural and engineered cyclotides, a novel molecular scaffold for peptide-based therapeutics. - Curr Mol Pharmacol [2010] Nov 1;3(3):153-63 PubMed Austin J,Kimura RH,Woo YH,Camarero JA - In vivo biosynthesis of an Ala-scan library based on the cyclic peptide SFTI-1. - Amino Acids [2010] May;38(5):1313-22 PubMed Berrade L,Kwon Y,Camarero JA - Photomodulation of protein trans-splicing through backbone photocaging of the DnaE split intein. - Chembiochem [2010] Jul 5;11(10):1368-72 PubMed Jagadish K,Camarero JA - Cyclotides, a promising molecular scaffold for peptide-based therapeutics. - Biopolymers [2010] ;94(5):611-6 PubMed Camarero JA - Optimizing the future for biotechnology therapies, the key role of protein engineering. - Adv Drug Deliv Rev [2009] Sep 30;61(11):897-8 PubMed Austin J,Wang W,Puttamadappa S,Shekhtman A,Camarero JA - Biosynthesis and biological screening of a genetically encoded library based on the cyclotide MCoTI-I. - Chembiochem [2009] Nov 2;10(16):2663-70 PubMed Berrade L,Camarero JA - Expressed protein ligation: a resourceful tool to study protein structure and function. - Cell Mol Life Sci [2009] Dec;66(24):3909-22 PubMed