Shi, Yigong - Rice University - Department of Chemistry

个人简介

Ph.D. Biophysics and Biophysical Chemistry (1995) Johns Hopkins University School of Medicine B.S. Biology and Mathematics (1989) Tsinghua University

近期论文

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Yigong Shi (2014) A Glimpse of Structural Biology through X-Ray Crystallography. Cell 159(5):995-1014 Qi Hu, Di Wu, Wen Chen, Zhen Yan, Chuangye Yan, Tianxi He, Qionglin Liang and Yigong Shi. (2014) Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome. Proc Natl Acad Sci USA. Oct 13. pii: 201418000. [Epub ahead of print] Tian Xie, Chuangye Yan, Rui Zhou, Yanyu Zhao, Linfeng Sun, Guanghui Yang, Peilong Lu, Dan Ma and Yigong Shi. (2014) Crystal structure of the ¦Ã-secretase component nicastrin. Proc Natl Acad Sci USA.16;111(37):13349-54. Sheng Wang, Renhong Yan, Xi Zhang, Qi Chu, and Yigong Shi. (2014) Molecular mechanism of pH-dependent substrate transport by an arginine-agmatine antiporter. Proc Natl Acad Sci USA.111(35):12734-9. Peilong Lu, Xiao-chen Bai, Dan Ma, Tian Xie, Chuangye Yan, Linfeng Sun, Guanghui Yang, Yanyu Zhao, Rui Zhou, Sjors H. W. Scheres & Yigong Shi. (2014) Three-dimensional structure of human gama-secretase. Nature 512(7513):166-70. Yigong Shi. (2014) Life, career, and structural biology. Physica Scripta 89:068004 (Commissioned Review) Jijie Chai, and Yigong Shi. (2014) Apoptosome and inflammasome: conserved machineries for caspase activation. National Science Review 1(1):101-108 (Commissioned Review) Lijun Zhou, Yulin Zhou, Jing Hang, Ruixue Wan, Guifeng Lu, Chuangye Yan & Yigong Shi. (2014) Crystal structure and biochemical analysis of the heptameric Lsm1-7 complex. Cell Res.24(4):497-500. Peilong Lu, Dan Ma, Chuangye Yan, Xinqi Gong, Mingjian Du & Yigong Shi. (2014) Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase. Proc Natl Acad Sci USA.111(5):1813-8. Lijun Zhou, Jing Hang, Yulin Zhou, Ruixue Wan, Guifeng Lu, Ping Yin, Chuangye Yan & Yigong Shi. (2014) Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature 506(7486):116-20. Ping Yin, Quanxiu Li, Chuangye Yan, Ying Liu, Junjie Liu, Feng Yu, Zheng Wang, Jiafu Long, Jianhua He, Hong-Wei Wang, Jiawei Wang, Jian-Kang Zhu, Yigong Shi & Nieng Yan. (2013) Structural insights into RIP3-mediated necroptotic signaling. Nature 504(7478):168-71. Tian Xie, Wei Peng, Chuangye Yan, Jianping Wu, Xinqi Gong, Yigong Shi. (2013) Structural insights into RIP3-mediated necroptotic signaling. Cell Rep. 5(1):70-8. Weijiao Huang, Tianyu Jiang, Wooyoung Choi, Shiqian Qi, Yuxuan Pang, Qi Hu, Yanhui Xu, Xinqi Gong, Philip D. Jeffrey, Jiawei Wang and Yigong Shi.(2013) Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev. 27(18):2039-48. Yigong Shi.(2013) Common folds and transport mechanisms of secondary active transporters. Annu Rev Biophys. 42:51-72. Dan Ma, Peilong Lu, Yigong Shi.(2013) Substrate Selectivity of the Acid-activated Glutamate-GABA Antiporter GadC from E. coli. J Biol Chem. 288(21):15148-53. Epub: 2013 Apr 15. Tingliang Wang, Guobin Fu, Xiaojing Pan, Jianping Wu, Xinqi Gong, Jiawei Wang & Yigong Shi.(2013) Structure of a bacterial energy-coupling factor transporter. Nature 497(7448):272-6. Epub: 2013 Apr 14. Qi Hu, Di Wu, Wen Chen, Zhen Yan, Yigong Shi.(2013) Proteolytic Processing of Caspase-9 Zymogen Is Required for Apoptosome-mediated Activation of Caspase-9. J Biol Chem. 288(21):15142-7. Epub: 2013 Apr 9. Hanchi Yan, Weiyun Huang, Chuangye Yan, Xinqi Gong, Sirui Jiang, Yu Zhao, Jiawei Wang, Yigong Shi.(2013) Structure and mechanism of a nitrate transporter. Cell Rep. 3(3):716-23 Tian Xie, Wei Peng, Yexing Liu, Chuangye Yan, Jenny Maki, Alexei Degterev, Junying Yuan, Yigong Shi.(2013) Structural Basis of RIP1 Inhibition by Necrostatins. Structure 21(3):493-499. Weijiao Huang, Wooyoung Choi, Yuling Chen, Qi Zhang, Haiteng Deng, Wei He and Yigong Shi.(2013) A proposed role for glutamine in cancer cell growth through acid resistance. Cell Res. 23(5):724-7 Epub: Jan 29. Peilong Lu, Dan Ma, Yuling Chen, Yingying Guo, Guo-Qiang Chen, Haiteng Deng1, and Yigong Shi.(2013) L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia. Cell Res. 23(5):635-44. Epub: Jan 22.