桑鹏 - 大理大学 - 农学与生物科学学院

个人简介

教育经历 2010-2014,理学博士,生物信息学,云南大学 2007-2010,理学硕士,生物化学与分子生物学,云南大学 2003-2007,农学学士,园艺,西南林学院工作经历 2017-至今,讲师,大理大学 2015-2017,博士后,昆明医科大学第一附属医院社会服务工作科研兴趣 1、人类疾病相关蛋白的结构和动力学研究 2、极端温度酶的适应机理项目成果 1、国家自然科学基金地区项目，31860243，人类P5CR蛋白致皮肤松弛症相关突变体的结构和动力学研究。执教课程生物信息学（本科生）,讲课,大理大学,2017年－至今秋季学期基因工程,讲课,大理大学,2018年－至今秋季学期

研究领域

科研兴趣 1、人类疾病相关蛋白的结构和动力学研究 2、极端温度酶的适应机理

近期论文

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(1)PengSang#,XingDu#,LiquanYang,ZhaohuiMeng*,ShuqunLiu*,Molecularmotionsandfree-energylandscapeofserineproteinaseKinrelationtoitscold-adaptation,acomparativemoleculardynamicssimulationstudyandtheunderlyingmechanisms,RSCAdv,2017,7,28580. (2)PengSang#,YuehuiXie#,LinhuaLi,YujiaYe,WeiHu,JingWang,WenWan,RuiLi,LinlingMa,ZhiLi,ShuqunLiu*,ZhaohuiMeng*,EffectoftheR119GMutationonHumanP5CRStructureandItsInteractionswithNAD:InsightsDerivedfromMolecularDynamicsSimulationandFreeEnergyAnalysis,COMPUTBIOLCHEM,2017,67:141-149. (3)PengSang#,WeiHu#,YujiaYe,LinhuaLi,ChaoZhang,YuehuiXie*,ZhaohuiMeng*,Insilicoscreening,moleculardocking,andmoleculardynamicsstudiesofSNP-derivedhumanP5CRmutants,JBIOMOLSTRUCTDYN,2017,35:2441-2453. (4)XingDu#,PengSang#,YuanlingXia,JingLiang,ShimengAi,XinglaiJi,YunxinFu,ShuqunLiu*,Comparativethermalunfoldingstudyofpsychrophilicandmesophilicsubtilisin-likeserineproteasesbymoleculardynamicssimulations,JBIOMOLSTRUCTDYN,2017,35:1500-1517. (5)PengSang#,QiongYang#,XingDu,NanYang,LiquanYang,XinglaiJi,YunxinFu,ZhaohuiMeng*,ShuqunLiu*,EffectoftheSolventTemperaturesonDynamicsofSerineProteaseProteinaseK,INTJMOLSCI,2016,17,254. (6)PengSang,LiquanYang,XinglaiJi,YunxinFu,ShuqunLiu*,InsightDerivedfromMolecularDynamicsSimulationsintoMolecularMotions,ThermodynamicsandKineticsofHIV-1gp120,PLoSONE,2014,9(8):e104714. (7)LinhuaLi#,YujiaYe#,PengSang,YiruiYin,WeiHu,JingWang,ChaoZhang,DeyunLi,WenWan,RuiLi,LongjunLi,LinlingMa,YuehuiXie*,ZhaohuiMeng*,EffectofR119GMutationonHumanP5CR1DynamicPropertyandEnzymaticActivity,BIOMEDRESINT,2017:e4184106. (8)Li-QuanYang,PengSang,Yue-HuiXie,YanTao,Yun-XinFu,Ke-QinZhang,Shu-QunLiu*.Proteindynamicsandmotionsinrelationtotheirfunctions:severalcasestudiesandtheunderlyingmechanisms.JBIOMOLSTRUCTDYN,2014,32:372-393. (9)YangLQ#,SangP#,ZhangRP,LiuSQ.Substrate-inducedchangesindynamicsandmolecularmotionsofcuticle-degradingserineproteasepl646:amoleculardynamicsstudy.RSCAdv,7(67),42094-42104. (10)XieYH,SangP,TaoY,LiuSQ.Proteinfoldingandbindingfunnels:acommondrivingforceandacommonmechanism.JBiomolStructDyn,2013,31(sup1):100-101.