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研究领域

合成生物学;酶的挖掘与改造;生物分子机器构建;新型生物催化剂的应用。

近期论文

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“Discriminating acidic and alkaline enzymes using a random forest model with secondary structure amino acid composition”, G.-Y. Zhang, H.-C. Li , B.-S. Fang, PROCESS BIOCHEMISTRY, 2009, 44, 654-660. “BestCodon: Novel software for codon bias analysis”, J.-C. Yu, L. Shui, B.-S. Fang, JOURNAL OF BIOTECHNOLOGY, 2008, 136: 349-350. “Predicting the cofactors of oxidoreductases based on amino acid composition distribution and Chou's amphiphilic pseudo-amino acid composition”, G.-Y. Zhang, B.-S. Fang, JOURNAL OF THEORETICAL BIOLOGY, 2008, 253, 310-315. “Predicting Lipase Types by Improved Chou's Pseudo-Amino Acid Composition”, G.-Y. Zhang, H.-C. Li, J.-Q. Gao, B.-S. Fang, PROTEIN AND PEPTIDE LETTERS, 2008, 15, 1132-1137. “Structural identification of ginseng polysaccharides and testing of their antioxidant activities”, D.-H. Luo, B.-S. Fang, CARBOHYDRATE POLYMERS 2008, 72, 376–381, “Heterologous expression, purification, and characterization of xylose reductase from Candida shehatae”, X.-X. Wang, B.-S. Fang, J.-X. Luo, et al. BIOTECHNOL LETT 2007, 29: 1409-1412,. “Simultaneous HPLC determination of four key metabolites in the metabolic pathway for production of 1,3-propanediol from glycerol”, H.-W. Chen, B.-S. Fang, Z.-D. Hu, CHROMATOGRAPHIA 2007, 65: 629-632. “LogitBoost classifier for discriminating thermophilic and mesophilic proteins”, G.-Y. Zhang, B.-S. Fang, J BIOTECHNOL 2007,127: 417-424, “Support vector machine for discrimination of thermophilic and mesophilic proteins based on amino acid composition”, G.-Y. Zhang, B.-S. Fang, PROTEIN PEPTIDE LETT 2006,13: 965-970. “A uniform design-based back propagation neural network model for amino acid composition and optimal pH in G/11 xylanase”, G.-Y. Zhang, B.-S. Fang, J CHEM TECHNOL BIOT 2006, 81: 1185-1189. “The influence of dipeptide composition on optimum temperature of alcohol dehydrogenase”, G.-Y. Zhang, B.-S. Fang, ENZYME MICROB TECH 2006, 39: 811-816. “Application of amino acid distribution along the sequence for discriminating mesophilic and thermophilic proteins”, G.-Y. Zhang, B.-S. Fang, PROCESS BIOCHEM 2006, 41: 1792-1798. “Discrimination of thermophilic and mesophilic proteins via pattern recognition methods”, G.-Y. Zhang, B.-S. Fang, PROCESS BIOCHEM 2006, 41: 552-556. “Optimization of expression of dhaT gene encoding 1,3-propanediol oxidoreductase from Klebsiella pneumoniae in Escherichia coli using the methods of uniform design and regression analysis”, Y. Cao, Q.-R. Xia, B.-S. Fang, J CHEM TECHNOL BIOT 2006, 81: 109-112. “Optimization of process parameters for key enzymes accumulation of 1,3-propanediol pro uction from Klebsiella pneumoniae”, H.-W. Chen, B.-S. Fang, Z.-D. Hu, BIOCHEM ENG J 2005, 25: 47-53. “Optimization of polymerase chain reaction-amplified conditions using the uniform design method”, Y. Cao, Y.-Y.Zheng, B.-S. Fang, J CHEM TECHNOL BIOT 2004, 79: 910-913. “Cloning and sequence analysis of the dhaT gene of the 1,3-propanediol regulon from Klebsiella pneumoniae”, Y.-Y. Zheng, Y. Cao, B.-S. Fang, BIOTECHNOL LETT 2004, 26: 251-255. “Using genetic algorithms coupling neural networks in a study of xylitol production: medium optimization”, B.-S. Fang H.-W. Chen, X.-L. Xie, et al. PROCESS BIOCHEM 2003, 38: 979-985,.

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