张志凌 - 武汉大学 - 化学与分子科学学院

个人简介

1997年7月于吉林大学化学系获学士学位，2002年11月于武汉大学化学与分子科学学院获博士学位。2001年7月提前留校工作，2003年10月赴法国巴黎高等师范学校（ENS）进行一年的博士后工作，2005年晋升副教授，2008年破格晋升教授。目前主要从事微流控芯片，生物电分析和纳米生物医学传感等方面的研究。2010年教育部新世纪优秀人才计划入选者，湖北省仪器仪表协会常务理事。国家基金委“新型生物医学探针技术基础及应用”创新研究群体及教育部“化学生物学应用基础研究”创新团队骨干成员。主持5项国家自然科学基金、1项国家863重大项目子课题以及1项863专题课题和1项教育部留学归国人员基金。2006年获教育部高等学校科学技术奖自然科学奖一等奖（第2完成人）。发表SCI论文160余篇，SCI他引3000余次。申请国家发明专利28项（已授权16项）。湖北省及国家精品课程（武汉大学《分析化学》）主讲教师之一。

研究领域

1) 磁控微流控芯片用于疾病标志物检测及肿瘤细胞分选 2) 基于微流控芯片的病毒与宿主细胞相互作用研究 3) 液滴微流控用于纳米材料合成及单颗粒数字化分析 4) 磁免疫电化学传感用于病原体检测

近期论文

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Liu, C.; Xiao, G. J.*; Yang, M. L.; Zou, B.*; Zhang Z. L.*; Pang D. W., Mechanofluorochromic Carbon Nanodots: Controllable Pressure-Triggered Blue- and Red-Shifted Photoluminescence. Angewandte Chemie-International Edition, (2018), 57(7), 1893-1897. Hong, S. L.; Zhang, Y. N.; Liu, Y. H.; Tang, M.; Pang, D. W.; Wong, G.; Chen, J. J.; Qiu, X. G.; Gao, G. F.; Liu, W. J.; Bi, Y. H.*; Zhang, Z. L.*. Cellular Beacons-mediated Counting for Ultrasensitive Detection of Ebola Virus on an Integrated Micromagnetic Platform. Analytical Chemistry, (2018), 90(12), 7310-7317. Wu, Z.; Guo, W. J; Bai, Y. Y.; Zhang, L.; Hu, J.; Pang, D. W; Zhang Z. L.*, Digital Single Virus Electrochemical Enzyme-Linked Immunoassay for Ultrasensitive H7N9 Avian Influenza Virus Counting. Analytical Chemistry, (2018), 90(3), 1683-1690. Pan, L. J.; Tu, J. W.; Ma, H. T.; Yang, Y. J.; Tian, Z. Q.; Pang D. W.; Zhang Z. L.*, Controllable synthesis of nanocrystals in droplet reactors. Lab on a Chip, (2018), 18(1), 41-56. Hu, J.; Jiang, Y. Z.; Wu, L.L.; Wu, Z.; Bi, Y.; Wong, G.; Qiu, X.; Chen, J.*; Pang, D. W; Zhang, Z. L.*, Dual-Signal Readout Nanospheres for Rapid Point-of-Care Detection of Ebola Virus Glycoprotein. Analytical Chemistry, (2017), 89(24), 13105-13111. Hong, S. L.; Wan, Y. T.; Tang, M.; Pang, D. W.; Zhang, Z. L.*, Multifunctional Screening Platform for the Highly Efficient Discovery of Aptamers with High Affinity and Specificity. Analytical Chemistry, (2017), 89(12), 6535-6542. Wu, Z.; Hu, J.; Zeng, T.; Zhang, Z. L.*, Chen, J.; Wong, G.; Qiu, X.; Liu, W., Gao, G. F.; Bi. Y.*; Pang, D. W., Ultrasensitive Ebola Virus Detection Based on Electroluminescent Nanospheres and Immunomagnetic Separation. Analytical Chemistry, (2017), 89(3), 2039-2048. Wu, L. L.; Wen, C. Y.; Hu, J.; Tang, M.; Qi, C. B.; Li, N.; Liu, C.; Chen, L.; Pang, D. W.; Zhang, Z. L.*, Nanosphere-based one-step strategy for efficient and nondestructive detection of circulating tumor cells. Biosensors and Bioelectronics, (2017), 94, 219-226. Wu, Z.; Zhou, C. H.; Pan, L. J.; Zeng, T.; Zhu, L.; Pang, D. W.; Zhang, Z. L.*, Reliable Digital Single Molecule Electrochemistry for Ultrasensitive Alkaline Phosphatase Detection. Analytical Chemistry, (2016), 88, 9166-9172. Tang, M.; Wen, C. Y.; Wu, L. L.; Hong, S. L.; Hu, J.; Xu, C. M.; Pang, D. W.; Zhang, Z. L.*, A chip assisted immunomagnetic separation system for the efficient capture and in situ identification of circulating tumor cells. Lab on a Chip, (2016), 16 (7), 1214-1223. Guo, P. L.; Tang, .M; Hong, S. L.; Yu, X.; Pang, D. W.; Pang, D. W.; Zhang, Z. L.*, Combination of dynamic magnetophoretic separation and stationary magnetic trap for highly sensitive and selective detection of Salmonella typhimurium in complex matrix. Biosensors and Bioelectronics, (2015), 74, 628-636. Zhou, C. H.; Zhao, J. Y.; Pang, D. W.; Zhang, Z. L.*, Enzyme-induced metallization as a signal amplification strategy for high sensitive colorimetric detection of avian influenza virus particles. Analytical Chemistry, (2014), 86 (5), 2752-2759. Xu, N.; Wang, J.; Zhang, Z. F.; Pang, D. W.; Wang, H. Z.; Zhang, Z. L.*, Anisotropic cell-to-cell spread of vaccinia virus on microgrooved substrate. Biomaterials, (2014), 35, 5049-5055. He S.; Yu X.; Wang X.; Tan J.; Yan S.; Wang P.; Huang B. H.; Zhang, Z. L.*; Li L.*, Fast Magnetic Isolation of Simple Sequence Repeat Markers in Microfluidic Channels. Lab on a Chip, (2014), 14 (8), 1410-1414. Zhang, R. Q.; Liu, S. L.; Zhao, W.; Zhang, W. P.; Yu, X.; Li, Y.; Li, A. J.; Pang, D. W.; Zhang, Z. L.*, A Simple Point-of-Care Microfluidic Immunomagnetic Fluorescence Assay for Pathogens. Analytical Chemistry, (2013), 85(5), 2645-2651. Yao, S.; Shu, Y.; Yang, Y. J.; Yu, X.; Pang D. W.; Zhang, Z. L.*, Picoliter droplets developed as microreactors for ultrafast synthesis of multi-color water-soluble CdTe quantum dots. Chemical Communications, (2013), 49, 7114-7116. (Inside back cover paper) Shu, Y.; Lu, W.; Liu, S. L.; Xu, N.; Wang, L.; Zhang, L.; Zheng, Z. H.; Pang, D. W.; Wang, H. Z., Zhang, Z. L.*, Site-specific labeling of baculovirus in an integrated microfluidic device. Lab on a Chip, (2013), 13 (5), 860-865. Yang, Y. J.; Feng, X.; Xu, N.; Pang, D. W.; Zhang, Z. L.*, Generation of sub-femtoliter droplet by T-junction splitting on microfluidic chips. Applied Physics Letters, (2013), 102 (12), 123502. Yu, X.; Xia, H. S.; Sun, Z. D.; Lin, Y.; Wang, K.; Yu, J.; Tang, H.; Pang, D. W.; Zhang, Z. L.*, On-chip dual detection of cancer biomarkers directly in serum based on self-assembled magnetic bead patterns and quantum dots. Biosensors and Bioelectronics, (2013), 41, 129-136. Feng, X.; Yi, Y.; Yu, X.; Pang, D. W.; Zhang, Z. L.* Generation of water-ionic liquid droplet pairs in soybean oil on microfluidic chip. Lab on a Chip, (2010), 10(3), 313-319.