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PROFESSIONAL CAREER Professor of Chemistry, Wuhan University 2013 to present Postdoc Research Fellow, Lawrence Berkeley National Lab 2012 to 2013 EDUCATION University of California-Los Angeles Ph.D in Chemistry, 2011 Advisor: Omar M. Yaghi Fudan University B.S. in Chemistry, 2007 Advisor: Dongyuan Zhao WORKING/TEACHING EXPERIENCE Thousand Talent Plan, China 2013 Award for Outstanding Chinese Student Studying Abroad,Consulate General of the People’s Republic of China in Los Angeles 2011 Excellence in Academics and Research Award, UCLA 2010


Carbon Dioxide Capture and Conversion CO2 (carbon dioxide) emission has caused a series of negative impacts to our environment, such as global warming and ocean acidification. It is imperative to find a solution not only to capture CO2 but also to convert it into useful product, such as methanol like the photosynthesis, but in a more efficient manner. One of our mission is to use nano-porous crystals to capture CO2 and convert it in-situ. Hydrogen Storage As a next generation fuel, hydrogen has attract enough attention in the past few decades. Aside from large scale production of H2 through water splitting, the storage is another critical issue. Our strategy is to develop porous materials with extremely large surface area to store H2 through physical adsorption Enrichment and Storage of Natural Gas Nowadays, natural gas become a popular fuel option due to less hazardous gas emission and lower cost in comparison to gasoline. With the design and application of novel porous materials, we aim at obtaining natural gas will higher quality during the mining process and store them more efficiently. Production of Green Porous Materials From Natural Materials The synthesis of porous materials usually involve extensive use of industrial chemical products, which eventually add more burden to the self-cleaning system of the earth.Replacement of traditional industrial chemicals with natural product such as glucose and amino acid to make useful porous materials will be a greener process.


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Extremely Large 3D Cages in Metal–Organic Frameworks for Nucleic Acid Extraction Gaoli Hu, Qi Liu, Yi Zhou, Wei Yan, Yuqing Sun, Shuang Peng, Chengbin Zhao, Xiang Zhou, and Hexiang Deng J. Am. Chem. Soc., 2023, 145, 13181–13194. Mesoporous Metal–Organic Frameworks for Catalytic RNA Deprotection and Activation Jin Liu, Xingyu Liu, Qi Liu, Jing Cao, Xinheng Lv, Shaoru Wang, Tian Tian, Xiang Zhou, Hexiang Deng, Angew. Chem. Int. Ed., 2023, e202302649 Activation of Pyroptosis Using AIEgen-Based sp2 Carbon-Linked Covalent Organic Frameworks Liang Zhang, Shucheng Wan, Jianyu Zhang, Mengjie Zhang, Qichao Yang, Boxin Zhang, Wuyin Wang, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam, Hexiang Deng, Zhijun Sun and Ben Zhong Tang J. Am. Chem. Soc., 2023, 145, 17689–17699. AIEgen-based Covalent Organic Frameworks for Preventing Malignant Ventricular Arrhythmias Via Local Hyperthermia Therapy Liang Zhang, Fuding Guo, Saiting Xu, Qiang Deng, Mengjie Xie, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam, Hexiang Deng, Hong Jiang, Lilei Yu and Ben Zhong Tang Adcanced Materials, 2023, org/10.1002/adma.202304620. Monodispersed Covalent Organic Framework Nanocrystals in Aqueous Solution for DNA Inclusion Xinheng Lyu, Lezhi Yi, Liang Zhang, Jin Liu, Hexiang Deng, Sci. China Chem., 2023, 10.1007/s11426-023-1674-7 Molecular Compartments Created in Metal–Organic Frameworks for Efficient Visible-Light-Driven CO2 Overall Conversion Chengbin Zhao, Zhuo Jiang, Yin Liu, Yi Zhou, Panchao Yin, Yubin Ke, and Hexiang Deng J. Am. Chem. Soc., 2022, 144, 23560-23571. Determining Factors in the Growth of MOF Single Crystals Unveiled by in situ Interface Imaging Jinli Han, Xudong He, Jin Liu, Ruijian Ming, Mohan Lin, Hui Li, Xiaochun Zhou, Hexiang Deng, Chem, 2022, 8, 1637-1657. High-Entropy-Alloy Nanoparticles Synthesized by Laser Metallurgy using a Multivariate MOF Wei Yan, Haoqing Jiang, Chengbin Zhao, Yucong Xia, Hengjiang Cong, Lin Tang, Gary J. Cheng, Jianhua He, Hexiang Deng, Mater. Chem. Front., 2022, 6, 2796-2802. Packing Metal-Organic Frameworks into an Opal Structure Haoqing Jiang, Shujuan Liu, Hexiang Deng​, ACS Cent. Sci., 2022, 8, 689-691. Covalent Organic Frameworks Catalyzed by Organic Lewis Acid Xiangqian Shi, Lezhi Yi, Hexiang Deng, Sci China Chem, 2022, 65, 1315-1320. Staggered Stacking Covalent Organic Frameworks for Boosting Cancer Immunotherapy Liang Zhang, Yao Xiao, Qichao Yang, Leilei Yang, Shucheng Wan, Shuo Wang, Lu Zhang, Hexiang Deng, Zhijun Sun, Adv. Funct. Mater., 2022, 32, 2201542. Laser Driven cConversion of MOFs to Rare Earth Metal Oxide Nanoparticles Xinyu Dou, Jin Liu, Xuan Gong, Haoqing Jiang, Hexiang Deng,APL Mater, 2022, 10, 041110. Multivariate MOF for Optimizing Atmospheric Water Harvesting Ao Ma, Hengjiang Cong, Hexiang Deng,Green Energy & Environment, 2022, 7, 575-577. Engineering Multienzyme-mimicking Covalent Organic Frameworks as Pyroptosis Inducers for Boosting Antitumor Immunity Liang Zhang, Qichao Yang, Shuo Wang, Yao Xiao, Shucheng Wan, Hexiang Deng and Zhijun Sun, Advanced Materials, 2021, 34, 2108174. Long Excited State Lifetime of Thermally Activated Delayed Fluorescent Photosensitizer Integrated into Metal-Organic Framework Enables Efficient CO2 Photoreduction Binglin Bie, Zhuo Jiang, Jing Zhang, Hexiang Deng and Chuluo Yang, Chemical Engineering Journal, 2021, 431, 133897. Enzymatic Deamination of the Epigenetic Nucleoside N6-methyladenosine Regulates Gene Expression Zhuoran Jiang, Chao Wang, Zixin Wu, Kun Chen, Wei Yang, Hexiang Deng, Heng Song and Xiang Zhou, Nucleic Acids Research, 2021, 49, 12048-12068. Uncovering Growth Species of Multivariate MOFs in Liquid Phase by Mass Spectrometry Jinli Han, Suming Chen, Xiaochun Zhou and Hexiang Deng, Chinese Chemical Letters, 2021, 33, 3993-3998. 25 years of Reticular Chemistry Ralph Freund, Stefano Canossa, Seth M. Cohen, Wei Yan, Hexiang Deng, Vincent Guillerm, Mohamed Eddaoudi, David G. Madden, David Fairen Jimenez, Hao Lyu, Lauren K. Macreadie, Zhe Ji, Yuanyuan Zhang, Bo Wang, Frederik Haase, Christof Wöll, Orysia Zaremba, Jacopo Andreo, Stefan Wuttke and Christian S. Diercks, Angew. Chem. Int. Ed., 2021, 60, 23946-23974. Three-Dimensional Covalent Organic Frameworks with Cross-Linked Pores for Efficient Cancer Immunotherapy Liang Zhang, Leilei Yang, Shucheng Wan, Qichao Yang, Yao Xiao, Hexiang Deng and Zhijun Sun, Nano Letters, 2021, 21, 7979-7988. Two-Photon Absorption Induced Cancer Immunotherapy Using Covalent Organic Frameworks Leilei Yang, Liang Zhang, Shucheng Wan, Shuo Wang, Zhizhong Wu, Qichao Yang, Yao Xiao, Hexiang Deng, and Zhijun Sun, Advanced Functional Materials, 2021, 31, 2103056. Structures Suggest an Approach for Converting Weak self-peptide Tumor Antigens into Superagonists for CD8 T cells in Cancer Pengcheng Wei, Kimberly R. Jordan, Jonathan D. Buhrman, Jun Lei, Hexiang Deng, Philippa Marrack, Shaodong Dai, John W. Kappler, Jill E. Slansky, and Lei Yin, Proceedings of the National Academy of Sciences, 2021, 118, 23. Reticular Chemistry at the Atomic, Molecular, and Framework Scales Yuebiao Zhang, Qiaowei Li and Hexiang Deng, Nano Research, 2021, 14, 335-337. Sequence Control of Metals in MOF by Coordination Number Precoding for Electrocatalytic Oxygen Evolution Hongnan Jia, Qi Han, Wei Luo, Hengjiang Cong and Hexiang Deng, Chem Catalysis, 2021, 2, 1-18. Immune-based Mutation Classification Enables Neoantigen Prioritization and Immune Feature Discovery in Cancer Immunotherapy Peng Bai, Yongzheng Li, Qiuping Zhou, Jiaqi Xia, Pengcheng Wei, Hexiang Deng, Min Wu, Sanny K. Chan, John W. Kappler, Yu Zhou, Eric Tran, Philippa Marrack and Lei Yin, OncoImmunology, 2021, 10, 1868130. Covalent Organic Frameworks for Optical Applications Liang Zhang, Lezhi Yi, Zhijun Sun, and Hexiang Deng,Aggregate, 2021, 2, e24. Filling Metal-Organic Framework Mesopores with TiO2 for CO2 Photoreduction Zhuo Jiang, Xiaohui Xu, Yanhang Ma, Hae Sung Cho, Deng Ding, Chao Wang, Jie Wu, Peter Oleynikov, Mei Jia, Jun Cheng, Yi Zhou, Osamu Terasaki, Tianyou Peng, Ling Zan, and Hexiang Deng, Nature 2020, 586, 549-554. Anisotropic Reticular Chemistry Wentao Xu, Binbin Tu, Qi Liu, Yufei Shu, Cong-Cong Liang, Christian S. Diercks, Omar M. Yaghi, Yue-Biao Zhang, Hexiang Deng, and Qiaowei Li, Nature Review Materials, 2020, 5, 764-779. Molecular Vises for Precisely Positioning Ligands near Catalytic Metal Centers in Metal-Organic Frameworks Wei Yan, Shenhui Li, Tao Yang, Yucong Xia, Xinrui Zhang, Chao Wang, Zier Yan, Feng Deng, Qianghui Zhou, and Hexiang Deng, J. Am. Chem. Soc., 2020, 142, 16182-16187. Structures and Structural Evolution of Sublayer Surfaces of MOF Crystals Xiaocang Han, Pan Liu, Fang Lin, Wenqian Chen, Ruichun Luo, Qi Han, Zhuo Jiang, Xiaodong Wang, Shuangxi Song, Kolan Madhav Reddy, Hexiang Deng, and Mingwei Chen, Angew. Chem. Int. Ed., 2020, 59, 21419-21424. Hyperpolarized Xe NMR Signal Advancement by Metal-Organic Framework Entrapment in Aqueous Solution Qingbin Zeng, Binglin Bie, Qianni Guo, Yaping Yuan, Qi Han, Xiaocang Han, Mingwei Chen, Xu Zhang, Yunhuang Yang, Maili Liu, Pan Liu, Hexiang Deng, and Xin Zhou, Proceedings of the National Academy of Sciences, 2020, 117, 17558-17563. Reticulation of 2D Semiconductors by Metal-Organic Approach for Efficient Hydrogen Evolution Hongmei Dai, Jiao Sun, Yi Zhou, Zirui Zhou, Wei Luo, Guangfeng Wei, and Hexiang Deng, ACS Sustainable Chem. Eng., 2020, 8, 8102-8110. Local Structure Evolvement in MOF Single Crystals Unveiled by Scanning Transmission Electron Microscopy Yi Zhou, Xiaohui Xu, Anna Carlsson, Sorin Lazar, Zhichao Pan, Yanhang Ma, Osamu Terasaki, and Hexiang Deng, Chem. Mater., 2020, 32, 4966-4972. Graphene-Metal-Metastructure Monolith via Laser Shock-Induced Thermochemical Stitching of MOF Crystals Haoqing Jiang, Lei Tong, Huidong Liu, Jin Xu, Shengyu Jin, Chao Wang, Xuejiao Hu, Lei Ye, Hexiang Deng, Gary J. Cheng, Matter, 2020, 2, 1339-1684. Covalent Organic Framework for Efficient Two-Photon Absorption Liang Zhang, Yi Zhou, Mei Jia, Yiwen He, Wei Hu, Qi Liu, Jing Li, Xiaohui Xu, Chao Wang, Anna Carlsson, Sorin Lazar, Arno Meingast, Yanhang Ma, Jun Xu, Wen Wen, Zhihong Liu, Jun Cheng, Hexiang Deng, Matter, 2020, 2, 1049-1063. Twist and Sliding Dynamics between Interpenetrated Frames in Ti-MOF Revealing High Proton Conductivity Jing Cao, Wenjie Ma, Kangjie Lyu, Lin Zhuang, Hengjiang Cong, Hexiang Deng, Chem. Sci., 2020, 11, 3978-3985. Efficient Separation of Nucleic Acids with Different Secondary Structures by Metal-Organic Frameworks Shuang Peng, Binglin Bie, Hongnan Jia, Heng Tang, Xiong Zhang, Yuqing Sun, Qi Wei, Fan Wu, Yushu Yuan, Hexiang Deng, Xiang Zhou, J. Am. Chem. Soc., 2020, 142, 5049-5059. Spontaneous Self-Intercalation of Copper Atoms into Transition Metal Dichalcogenides Xiaochen Liu, Shuyang Zhao, Xueping Sun, Liangzi Deng, Xiaolong Zou, Youcheng Hu, Yunxiao Wang, Chingwu Chu, Jia Li, Jingjie Wu, Fusheng Ke, Pulickel M. Ajayan, Sci. Adv., 2020, 6, 4092. Multivariate MOFs for Laser Writing of Alloy Nanoparticle Patterns Ruiqian Ma, Haoqing Jiang, Chao Wang, Chengbin Zhao, Hexiang Deng, Chem. Commun., 2020, 56, 2715-2718. Metal-Organic Frameworks for the Exploitation of Distance between Active Sites in Efficient Photocatalysis Xuan Gong, Yufei Shu, Zhuo Jiang, Lingxiang Lu, Xiaohui Xu, Chao Wang, Hexiang Deng, Angew. Chem. Int. Ed., 2020, 59, 5326-5331. Metal-Organic Framework for Transparent Electronics Jie Wu, Jinhang Chen, Chao Wang, Yi Zhou, Kun Ba, Hu Xu, Wenzhong Bao, Xiaohui Xu, Anna Carlsson, Sorin Lazar, Arno Meingast, Zhengzong Sun, Hexiang Deng, Adv. Sci., 2020, 7, 1903003. Uniform Bi-Sb Alloy Nanoparticles Synthesized from MOFs by Laser Metallurgy for Sodium-Ion Batteries Wei Zhang, Wei Yan, Haoqing Jiang, Chao Wang, Yi Zhou, Fusheng Ke, Hengjiang Cong, Hexiang Deng, ACS Sustainable Chem. Eng., 2020, 8, 335-342.