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1、金属催化的新型有机反应研究 2、金属催化的不对称反应的研究 3、杂环化合物的研究

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Kou, Xuezhen; Zhao, Mengdi; Qiao, Xixue; Zhu, Yamin; Tong, Xiaofeng; Shen, Zengming* “Copper-Catalyzed Aromatic C-H Bond Cyanation by C-CN Bond Cleavage of Inert Acetonitrile” Chem. Eur. J. 2013, 19, 16880-16886. (Highlighted as a frontispiece.) Mo Song, Zhu Yamin, Shen Zengmging*, “Copper-catalyzed aromatic C–H bond halogenation with lithium halides under aerobic conditions” Org. Biomol. Chem. 2013, 11, 2756-2760. (Hot Paper, highlighted as a cover.) Kou Xuezhen, Fan Jiajun, Tong Xiaofeng, Shen Zengming*, “Recent Progress in the Research of Transition-Metal-Catalyzed C—CN Bond Cleavage “ Chin. J. Org. Chem. 2013, 33, 1407-1422. Shen, Zengming*; Ni, Zhenjie; Mo, Song; Wang, Jing; Zhu, Yamin; “Palladium-Catalyzed Intramolecular Decarboxylative Coupling of Arene Carboxylic Acids/Esters with Aryl Bromides” Chem. Eur. J. 2012, 18, 4859-4865. Wang, Ruiping; Mo, Song; Lu, Yongzhong; Shen, Zengming* "Domino Sonogashira Coupling /Cyclization Reaction Catalyzed by Copper and ppb Levels of Palladium: A Concise Route to Indoles and Benzo[b]furans" Adv. Synth. Catal. 2011,353, 713-718. Lu, Yongzhong; Wang, Ruiping; Qiao, Xixue; Shen, Zengming* Copper-Catalyzed Aromatic C–H Bond Halogenation Using Lithium Halides as Halogenating Reagents, Synlett, 2011,1038. (Special Issue of Synlett dedicated to Professors Lu Xiyan and Dai Li-Xin) Shen, Zengming; Dornan, Peter K.; Khan, Hasan A; Woo, Tom; Dong, Vy M. “Mechanistic insights into the rhodium-catalyzed intramolecular ketone hydroacylation” J. Am. Chem. Soc. 2009, 131, 1077-1091. Shen, Zengming; Dong, Vy M. “Benzofurans prepared by C-H bond functionalization with acylsilanes” Angew. Chem. Int. Ed. 2009, 48, 784-786. (For a highlight, see: Synfacts, 2009, 4, 409) Shen, Zengming; Khan, Hasan A.; Dong, Vy M. “Rh-Catalyzed carbonyl hydroacylation: an enantioselective approach to lactones” J. Am. Chem. Soc. 2008, 130, 2916-2917. (See the highlight in Chemistry World featuring this work: James Mitchell Crow, "Rhodium fast tracks route to lactones." Editorial Board of SYNFACTS selects this article as the Synfact of the month, see: Synfacts, 2008, 5, 485). Shen, Zengming; Lu, Xiyan “Cupric halide-mediated intramolecular halocyclization of N-electron-withdrawing group substituted 2-alkynylanilines for the synthesis of 3-haloindoles,” Adv. Synth. Catal. 2009, 351, 3107-3112. Shen, Zengming; Khan, Hasan A.; Dong, Vy M. “Novel catalytic approach to chiral lactones” 235th ACS National Meeting, New Orleans, LA, United States, April 6-10, 2008. Shen, Zengming; Lu, Xiyan; Lei, Aiwen. “Highly enantioselective hydrogenation of exocyclic double bond of N-tosyloxazolidinones catalyzed by a neutral rhodium complex and its synthetic applications” Tetrahedron 2006, 62, 9237-9246. Shen, Zengming; Lu, Xiyan “Palladium(II)-catalyzed tandem intramolecular aminopalladation of alkynylanilines and conjugate addition for synthesis of 2,3-disubstituted indole derivatives” Tetrahedron 2006, 62, 10896-10899.

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