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个人简介

教育经历 1981-1985:华东理工大学化学系,学士 1985-1988:华东理工大学化学系,硕士 1994-1997:日本大阪大学工学部应用化学系,博士 工作经历 1988-1993:华东理工大学专用化学品研究所,助教、讲师 1997-2001:日本大阪大学工学部应用化学系,助理教授 2001-2003:日本三菱化学株式会社横滨综合研究所,主任研究员 2003-至今:上海交通大学化学化工学院,教授 2009-至今:上海交通大学药学院,教授 2013-至今:上海交通大学,教授 2017-至今:上海市手性药物分子工程重点实验室,主任

研究领域

有机合成及不对称催化 药物及其关键中间体的高效合成方法

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Youbin Peng, Xiaohong Huo, Yicong Luo, Liang Wu, and Wanbin Zhang*, "Enantio- and Diastereodivergent Synthesis of Spirocycles through Dual-Metal-Catalyzed [3+2] Annulation of 2-Vinyloxiranes with Nucleophilic Dipoles", Angew. Chem. Int. Ed. 2021, 60, accepted. DOI: 10.1002/anie.202111842. Yunnan Xu, Delong Liu, Yu Deng, Yi Zhou, and Wanbin Zhang*, "Rh-Catalyzed Asymmetric Hydrogenation of 3-Benzoylaminocoumarins for the Synthesis of Chiral 3-Amino Dihydrocoumarins", Angew. Chem. Int. Ed. 2021, 60, accepted. DOI: 10.1002/anie.202110286. Jiacheng Zhang, Xiaohong Huo, Junzhe Xiao, Ling Zhao, Shengming Ma*, and Wanbin Zhang*, "Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis", J. Am. Chem. Soc. 2021, 143, 12622-12632. Jian Zhang, Tiantian Chen, Yuanhao Wang, Fengfan Zhou, Zhenfeng Zhang*, Ilya D. Gridnev*, and Wanbin Zhang*, "Asymmetric Hydrogenation of γ-Branched Allylamines for the Efficient Synthesis of γ-Chirogenic Amines", Nat. Sci. 2021, 1, accepted. DOI: 10.1002/ntls.10021. Yanhua Hu, Zhenfeng Zhang, Yangang Liu, and Wanbin Zhang*, "Cobalt-Catalyzed Chemo- and Enantioselective Hydrogenation of Conjugated Enynes", Angew. Chem. Int. Ed. 2021, 60, 16989-16993. Chong Liu, Jing Yuan, Zhenfeng Zhang*, Ilya D. Gridnev, and Wanbin Zhang*, "Asymmetric Hydroacylation Involving Alkene Isomerization for the Construction of C3-Chirogenic Center", Angew. Chem. Int. Ed. 2021, 60, 8997-9002. VIP paper. Muxing Zhou, Tatiana Gridneva, Zhenfeng Zhang, Ende He, Yangang Liu, and Wanbin Zhang*, "Chiral Bicyclic Imidazole-Catalyzed Acylative Dynamic Kinetic Resolution for the Synthesis of Chiral Phthalidyl Esters", Angew. Chem. Int. Ed. 2021, 60, 1641-1645. VIP paper. Xiaohong Huo, Ling Zhao, Yicong Luo, Yue Wu, Yuwen Sun, Guanlin Li, Tatiana Gridneva, Jiacheng Zhang, Yong Ye, and Wanbin Zhang*, "Stereodivergent Pd/Cu Catalysis for Asymmetric Desymmetric Alkylation of Allylic Geminal Dicarboxylates", CCS Chem. 2021, 3, 1933-1944. Dan Liu, Bowen Li, Jianzhong Chen, Ilya D. Gridnev, Deyue Yan and Wanbin Zhang*, "Ni-Catalyzed Asymmetric Hydrogenation of N-Aryl Imino Esters for the Efficient Synthesis of Chiral α-Aryl Glycines", Nat. Commun. 2020, 11, 5935. Mo Wang, Lu Zhang, Xiaohong Huo, Zhenfeng Zhang, Qianjia Yuan, Panpan Li, Jianzhong Chen, Yashi Zou, Zhengxing Wu, and Wanbin Zhang*, "Catalytic Asymmetric Synthesis of the Anti-COVID-19 Drug Remdesivir", Angew. Chem. Int. Ed. 2020, 59, 20814-20819. VIP paper. Rui He, Xiaohong Huo, Ling Zhao, Feijun Wang, Liyin Jiang, Jian Liao,* and Wanbin Zhang*, "Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates", J. Am. Chem. Soc. 2020, 142, 8097-8103. Guanlin Li, Xiaohong Huo, Xieyang Jiang, and Wanbin Zhang*, "Asymmetric Synthesis of Allylic Compounds via Hydrofunctionalisation and Difunctionalisation of Dienes, Allenes, and Alkynes", Chem. Soc. Rev. 2020, 49, 2060-2118. Inside front cover Yawen Hu, Jianzhong Chen, Bowen Li, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, "Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates", Angew. Chem. Int. Ed. 2020, 59, 5371-5375. Liang Wu, Guoqiang Yang, and Wanbin Zhang*, "Ni-Catalyzed Enantioconvergent Coupling of Epoxides with Alkenylboronic Acids: Construction of Oxindoles Bearing Quaternary Carbons", CCS Chem. 2019, 1, 623-631. Yanhua Hu, Zhenfeng Zhang, Jian Zhang, Yangang Liu, Ilya D. Gridnev, and Wanbin Zhang*, "Cobalt‐Catalyzed Asymmetric Hydrogenation of C=N Bond Enabled by Assisted Coordination and Non‐bonding Interaction", Angew. Chem. Int. Ed. 2019, 58, 15767-15771. Jian Zhang, Jia Jia, Xincheng Zeng, Yuanhao Wang, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, "Chemo- and Enantioselective Hydrogenation of a-Formyl Enamides: An Efficient Access to Chiral α-Amido Aldehydes", Angew. Chem. Int. Ed. 2019, 58, 11505-11512, VIP paper. Bowen Li, Jianzhong Chen, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, "Ni-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Imines", Angew. Chem. Int. Ed. 2019, 58, 7329-7334. VIP paper, Cover picture. Jianzhong Chen, Zhenfeng Zhang, Bowen Li, Feilong Li, Yulin Wang, Min Zhao, Ilya D. Gridnev, Tsuneo Imamoto, and Wanbin Zhang*, "Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of Sterically Hindered N-Tosylimines", Nat. Commun. 2018, 9, 5000. Xuezhen Kou, Qihang Shao, Chenghao Ye, Guoqiang Yang*, and Wanbin Zhang*, "Asymmetric Aza-Wacker-type Cyclization of N-Ts Hydrazine-Tethered Tetrasubstituted Olefins: Synthesis of Pyrazolines Bearing One Quaternary or Two Vicinal Stereocenters", J. Am. Chem. Soc. 2018, 140, 7587-7597. Mao Quan, Xiaoxiao Wang, Liang Wu, Ilya D. Gridnev, Guoqiang Yang*, and Wanbin Zhang*, "Ni(II)-Catalyzed Asymmetric Alkenylations of Ketimines", Nat. Commun. 2018, 9, 2258.

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