Khan, Md Asaduzzaman - 西南医科大学

个人简介

Dr. Md Asaduzzaman Khan, a Bangladeshi national, is currently working at the Research Center for Preclinical Medicine of Southwest Medical University as Research Professor. He completed his bachelor and Masters in Biochemistry and Molecular Biology from Jahangirnagar University, Bangladesh, and in 2013, he obtained his doctoral degree in Biochemistry and Molecular Biology from Central South University of China. For his doctoral enrollment, he received Chinese Government Scholarship. Dr. Khan then had postdoctoral training at Luzhou Medical College, under Zhejiang University and University of Macao. Dr. Khan also have teaching experience at BSMR Agricultural University of Bangladesh and Ton Duc Thang University of Vietnam. In 2017, joined to present position at Southwest Medical University. Till 2019, he has published over 80 scientific articles, of which 50+ are in SCI-indexed journals. He is the member of American Association for Cancer Research. Dr. Khan is the recipient of ‘Research Fund for International Young Scientists’ by National Natural Science Foundation of China (NSFC).

研究领域

His major research focus is molecular biology of cancer.

近期论文

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Characterization and molecular cloning of novel isoforms of human spermatogenesis associated gene SPATA3. Zhou B, Wei C, Khan MA, Chen H, Fu J. Molecular biology reports. 2019; 46(4):3827-3834. A novel splicing mutation in the PRPH2 gene causes autosomal dominant retinitis pigmentosa in a Chinese pedigree. Cheng J, Fu J, Zhou Q, Xiang X, Wei C, Yang L, Fu S, Khan MA, Lv H, Fu J. Journal of cellular and molecular medicine. 2019; 23(5):3776-3780. Novel splicing variant c. 208+2T>C in BBS5 segregates with Bardet-Biedl syndrome in an Iranian family by targeted exome sequencing. Imani S, Cheng J, Fu J, Mobasher-Jannat A, Wei C, Mohazzab-Torabi S, Jadidi K, Khosravi MH, Shasaltaneh MD, Yang L, Khan MA, Fu J. Bioscience reports. 2019; 39(3). Cordycepin Downregulates Cdk-2 to Interfere with Cell Cycle and Increases Apoptosis by Generating ROS in Cervical Cancer Cells: in vitro and in silico Study. Tania M, Shawon J, Saif K, Kiefer R, Khorram MS, Halim MA, Khan MA. Current cancer drug targets. 2019; 19(2):152-159. Cordycepin in Anticancer Research: Molecular Mechanism of Therapeutic Effects. Khan MA, Tania M. Current medicinal chemistry. 2018; Potential risk of weed outbreak by increasing biochar's application rates in slow-growth legume, lentil (Lens culinaris Medik.). Safaei Khorram M, Fatemi A, Khan MA, Kiefer R, Jafarnia S. Journal of the science of food and agriculture. 2018; 98(6):2080-2088. Genetic identification and molecular modeling characterization reveal a novel PROM1 mutation in Stargardt4-like macular dystrophy. Imani S, Cheng J, Shasaltaneh MD, Wei C, Yang L, Fu S, Zou H, Khan MA, Zhang X, Chen H, Zhang D, Duan C, Lv H, Li Y, Chen R, Fu J. Oncotarget. 2018; 9(1):122-141. Evaluation of amplification refractory mutation system (ARMS) technique for quick and accurate prenatal gene diagnosis of CHM variant in choroideremia. Yang L, Ijaz I, Cheng J, Wei C, Tan X, Khan MA, Fu X, Fu J. The application of clinical genetics. 2018; 11:1-8. Thymoquinone Inhibits the Migration and Invasive Characteristics of Cervical Cancer Cells SiHa and CaSki In Vitro by Targeting Epithelial to Mesenchymal Transition Associated Transcription Factors Twist1 and Zeb1. Li J, Khan MA, Wei C, Cheng J, Chen H, Yang L, Ijaz I, Fu J. Molecules (Basel, Switzerland). 2017; 22(12). Thymoquinone, as an anticancer molecule: from basic research to clinical investigation. Asaduzzaman Khan M, Tania M, Fu S, Fu J. Oncotarget. 2017; 8(31):51907-51919. MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion. Imani S, Wei C, Cheng J, Khan MA, Fu S, Yang L, Tania M, Zhang X, Xiao X, Zhang X, Fu J. Oncotarget. 2017; 8(13):21362-21379. Evaluation of PIK3CA mutations as a biomarker in Chinese breast carcinomas from Western China. Cheng J, Fu S, Wei C, Tania M, Khan MA, Imani S, Zhou B, Chen H, Xiao X, Wu J, Fu J. Cancer biomarkers : section A of Disease markers. 2017; 19(1):85-92. An improved DNA marker technique for genetic characterization using RAMP-PCR with high-GC primers. Wei CL, Cheng JL, Khan MA, Yang LQ, Imani S, Chen HC, Fu JJ. Genetics and molecular research : GMR. 2016; 15(3). Development of two novel specific SCAR markers by cloning improved RAPD fragments from the medicinal mushroom Ganoderma lucidium (Leysser: Fr) Karst. Khan MA, Cheng JL, Mei ZQ, Wei CL, Fu JJ. Genetics and molecular research : GMR. 2016; 15(3). Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein. Wei C, Cheng J, Zhou B, Zhu L, Khan MA, He T, Zhou S, He J, Lu X, Chen H, Zhang D, Zhao Y, Fu J. Scientific reports. 2016; 6:29822. Relationship between SPOP mutation and breast cancer in Chinese population. Khan MA, Zhu L, Tania M, Xiao XL, Fu JJ. Genetics and molecular research : GMR. 2015; 14(4):12362-6. Development of SCAR Markers Based on Improved RAPD Amplification Fragments and Molecular Cloning for Authentication of Herbal Medicines Angelica sinensis, Angelica acutiloba and Levisticum officinale. Zhang C, Mei Z, Cheng J, He Y, Khan MA, Luo P, Imani S, Fu J. Natural product communications. 2015; 10(10):1743-7. Establishment and rapid detection of a heterozygous missense mutation in the CACNA1F gene by ARMS technique with double-base mismatched primers. Yang WC, Zhu L, Zhou BX, Tania S, Zhou Q, Khan MA, Fu XL, Cheng JL, Lv HB, Fu JJ. Genetics and molecular research : GMR. 2015; 14(3):11480-7. Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition. Khan MA, Tania M, Wei C, Mei Z, Fu S, Cheng J, Xu J, Fu J. Oncotarget. 2015; 6(23):19580-91. Establishment of stable cell line for inducing KAP1 protein expression. Liu X, Khan MA, Cheng J, Wei C, Zhang L, Fu J. Acta biologica Hungarica. 2015; 66(2):161-8.