个人简介

郭兴启，男，1963年10月生，山东嘉祥人。博士，教授，博士生导师。2005年5月至2019年3月任生命科学学院教学副院长。山东省教学名师，山东省优秀研究生指导教师，生物化学与分子生物学国家级教学团队负责人，生物技术国家级特色专业主任，生物技术与工程省级实验教学示范中心主任，山东省现代农业产业技术体系蜂产业创新团队岗位专家，山东省生物化学与分子生物学学会副理事长。曾获山东省教学成果特等奖1项（第二位）、二等奖1项（首位）、三等奖1项（首位）。主编出版国家级规划教材2部（中国农业出版社）、教学研究专著1部（高等教育出版社）、科学研究专著1部（科学出版社）。主持国家自然科学基金、国家转基因植物研究专项、农业部现代农业产业技术体系建设专项、山东省现代农业产业技术体系建设专项等多项科研课题。获得国家发明专利6项，以通讯作者在《FreeRadicalBiologyandMedicine》、《JournalofExperimentalBotany》等学术刊物上发表论文多篇。 教学工作 承担本科生《分子生物学》、《基础生物化学实验》；硕士研究生《分子生物学》、《高级生物化学实验技术》；博士研究生《植物逆境信号转导与基因工程》等课程的教学工作。

研究领域

研究方向 1.棉花抗病抗逆分子生物学 2.中华蜜蜂抗病抗逆分子生物学

科研项目 1.国家自然科学基金《棉花激酶GhMKK6基因的功能分析及其级联信号途经的鉴定》（No.31471424） 2.国家自然科学基金《棉花GhMPK7基因广谱抗病功能的分子机理研究》（No.31171837） 3.国家自然科学基金《温度对RNA沉默的抑制及其分子机理研究》（No.30370928） 4.国家自然科学基金《RNA介导抗性转基因植物的抗病机制及遗传规律》（No.30571215） 5.山东省现代农业产业技术体系蜂产业创新团队建设专项（No.SDAIT-24-04） 6.中国博士后科学基金《转基因植物中RNA介导抗性的遗传学》（No.2002031167） 7.山东省中青年科学家科研奖励基金《抗病毒转基因植物释放的环境风险性研究》（No.02BS025） 8.国家转基因植物研究重大专项《棉花高产性状激素调控基因的克隆和克隆新方法的研究》子课题（No.2009ZX08009-113B） 9.农业部现代农业产业技术体系建设专项《现代农业蜂产业技术体系建设》子课题（No.NYCYTX-43）

近期论文

查看导师最新文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.GuilinLi,HangZhao,ZhenguoLiu,HongfangWang,BaohuaXu*,XingqiGuo*.Thewisdomofhoneybeedefensesagainstenvironmentalstresses,FrontiersinMicrobiology,2018,9:722. 2.GuilinLi,HangZhao,LijunWang,YingWang,XingqiGuo*,BaohuaXu*.TheanimalnuclearfactorY:anenigmaticandimportantheterotrimerictranscriptionfactor,AmericanJournalofCancerResearch,2018;8(7):1106-1125. 3.GuilinLi,HangZhao,XuemeiZhang,YanmingZhang,HuayuZhao,XinxinYang,XingqiGuo*,BaohuaXu*.EnvironmentalStressResponsesofDnaJA1,DnaJB12andDnaJC8inApisceranacerana,FrontiersinGenetics,2018,9:445. 4.ChenWang,XiaowenHe,YuzhenLi,LijunWang,XuleiGuo,XingqiGuo*.ThecottonMAPKkinaseGhMPK20negativelyregulatesresistancetoFusariumoxysporumbymediatingtheMKK4-MPK20-WRKY40cascade,MolecularPlantPathology,2018,19(7):1624-1638. 5.ChenWang,XiaowenHe,XinxinWang,ShuxinZhang,XingqiGuo*.ghr-miR5272a-mediatedregulationofGhMKK6genetranscriptioncontributestotheimmuneresponseincotton,JournalofExperimentalBotany,2017,68(21-22):5895-5906. 6.ChenWang,WenjingLu,XiaowenHe,FangWang,YuliZhou,XuleiGuo,XingqiGuo*.ThecottonMitogen-ActivatedProteinKinaseKinase3functionsindroughttolerancebyregulatingstomatalresponsesandrootgrowth.PlantandCellPhysiology,2016,57(8):1629-1642. 7.FangWang,ChenWang,YanYan,HaihongJia,XingqiGuo*.OverexpressionofcottonGhMPK11decreasesdiseaseresistancethroughthegibberellinsignalingpathwayintransgenicNicotianabenthamiana.FrontiersinPlantScience,2016,7:689. 8.HaihongJia,LiliHao,XuleiGuo,ShuchangLiu,YanYan,XingqiGuo*.ARaf-likeMAPKKKGene,GhRaf19,negativelyregulatestolerancetodroughtandsaltandpositivelyregulatesresistancetocoldstressbymodulatingReactiveOxygenSpeciesincotton.PlantScience,2016,252:267-281. 9.YanYan,HaihongJia,FangWang,ChenWang,ShuchangLiu,XingqiGuo*.OverexpressionofGhWRKY27areducestolerancetodroughtstressandresistancetoRhizoctoniasolaniinfectionintransgenicNicotianabenthamiana.FrontiersinPhysiology,2015,6:265. 10.XiaoboChen,JiWang,MingZhu,HailongAn,DongdongLiu,LiliHao,XingqiGuo*.AcottonRaf-likeMAP3Kgene,GhMAP3K40,mediatesreducedtolerancetobioticandabioticstressinNicotianabenthamianabynegativelyregulatinggrowthanddevelopment.PlantScience,2015,240:10-24. 11.YifengHuaxia,FangWang,YanYan,FengLiu,HongfangWang,XingqiGuo*,BaohuaXu*.Anovel1-CysthioredoxinperoxidasegeneinApisceranacerana:characterizationofAccTpx4anditsroleinoxidativestresses.CellStress&Chaperones,2015,20(4):663-672. 12.XiaoboChen,PengboYao,XiaoqianChu,LiliHao,XingqiGuo*,BaohuaXu*.IsolationofargininekinasefromApisceranaceranaanditspossibleinvolvementinresponsetoadversestress.CellStress&Chaperones,2015,20(1):169-183. 13.YuzhenLi,LiangZhang,WenjingLu,XiulingWang,ChangaiWu,XingqiGuo*.OverexpressionofcottonGhMKK4enhancesdiseasesusceptibilityandaffectsabscisicacid,gibberellinandhydrogenperoxidesignallingintransgenicNicotianabenthamiana.MolecularPlantPathology,2014,15(1):94-108. 14.PengboYao,XiaoboChen,YanYan,FengLiu,YuanyingZhang,XingqiGuo*,BaohuaXu*.Glutaredoxin,glutaredoxin2,thioredoxin1andthioredoxinperoxidase3playimportantrolesinantioxidantdefenseinApisceranacerana.FreeRadicalBiologyandMedicine,2014,68:335-346. 15.HuiruYan,HaihongJia,XiaoboChen,LiliHao,HailongAn,XingqiGuo*.ThecottonWRKYtranscriptionfactorGhWRKY17functionsindroughtandsaltstressintransgenicNicotianabenthamianathroughABAsignalingandthemodulationofreactiveoxygenspeciesproduction.PlantandCellPhysiology,2014,55(12):2060-2076. 16.YuzhenLi,LiangZhang,XiulingWang,WeiZhang,LiliHao,XiaoqianChu,XingqiGuo*.CottonGhMPK6anegativelyregulatesosmotictoleranceandbacterialinfectionintransgenicNicotianabenthamiana,andplaysapivotalroleindevelopment.FEBSJournal,2013,280:5128-5144. 17.YuanyingZhang,HuiruYan,WenjingLu,YuzhenLi,XingqiGuo*,BaohuaXu*.AnovelOmega-classglutathioneS-transferasegeneinApisceranacerana:molecularcharacterisationofGSTO2anditsprotectiveeffectsinoxidativestress.CellStress&Chaperones,2013,18(4):503-516. 18.HuiruYan,HaihongJia,HongruGao,XingqiGuo*,BaohuaXu*.Identification,genomicorganization,andoxidativestressresponseofasigmaclassglutathioneS-transferasegene(AccGSTS1)inthehoneybee,Apisceranacerana.CellStress&Chaperones,2013,18(4):415-426. 19.PengboYao,WenjingLu,FeiMeng,XiulingWang,BaohuaXu*,XingqiGuo*.Molecularcloning,expressionandoxidativestressresponseofamitochondrialthioredoxinperoxidasegene(AccTpx-3)fromApisceranacerana.JournalofInsectPhysiology,2013,59(3):273-282. 20.LiangZhang,YuzhenLi,WenjingLu,FeiMeng,ChangaiWu,XingqiGuo*.CottonGhMKK5affectsdiseaseresistance,inducesHR-likecelldeath,andreducesthetolerancetosaltanddroughtstressintransgenicNicotianabenthamiana.JournalofExperimentalBotany,2012,63(10):3935-3952. 21.FeifeiYu,YifengHuaxia,WenjingLu,ChangaiWu,XuechengCao,XingqiGuo*.GhWRKY15,amemberoftheWRKYtranscriptionfactorfamilyidentifiedfromcotton(GossypiumhirsutumL.),isinvolvedindiseaseresistanceandplantdevelopment.BMCPlantBiology,2012,12(1):144. 22.HuiruYan,FeiMeng,HaihongJia,XingqiGuo*,BaohuaXu*.TheidentificationandoxidativestressresponseofazetaclassglutathioneS-transferase(GSTZ1)genefromApisceranacerana.JournalofInsectPhysilology,2012,58(6):782-791. 23.LiangZhang,DongmeiXi,LuLuo,FeiMeng,YuzhenLi,ChangaiWu,XingqiGuo*.CottonGhMPK2isinvolvedinmultiplesignalingpathwaysandmediatesdefenseresponsestopathogeninfectionandoxidativestress.FEBSJournal,2011,278(8):1367-1378. 24.LiangZhang,DongmeiXi,ShanweiLi,ZhengGao,ShuoliZhao,JingShi,ChangaiWu,XingqiGuo*.AcottongroupCMAPkinasegene,GhMPK2,positivelyregulatessaltanddroughttoleranceintobacco.PlantMolecularBiology,2011,77:17-31. 25.FeifeiYu,MingjiangKang,FeiMeng,XingqiGuo*,BaohuaXu*.MolecularcloningandcharacterizationofathioredoxinperoxidasegenefromApisceranacerana.InsectMolecularBiology,2011,20(3):367-378. 26.TaoboAi,LiangZhang,ZhengGao,ChangxiangZhu,XingqiGuo*.HighlyefficientvirusresistancemediatedbyartificialmicroRNAsthattargetthesuppressorofPVXandPVYinplants.PlantBiology,2011,13:304-316. 27.JingShi,HailongAn,LiangZhang,ZhengGao,XingqiGuo*.GhMPK7,anovelmultiplestress-responsivecottongroupCMAPKgene,hasaroleinbroadspectrumdiseaseresistanceandplantdevelopment.PlantMolecularBiology,2010,74:1-17. 28.YingZhang,JingShi,YanLiu,YiZhang,JiedaoZhang,XingqiGuo*.IdentificationofanovelNPR1-likegenefromNicotianaglutinosaanditsroleinresistancetofungal,bacterialandviralpathogens.PlantBiology,2010,12:23-34.