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成果及论文

8. L. O. Atta†, Z. Zhou†, G. Roelfes*. "In vivo Biocatalytic Cascades Featuring an Artificial-Enzyme-Catalyzed New-to-Nature Reaction"

   Angew. Chem. Int. Ed., 2023, 10.e202214191. (equal contribution)

  Open Access https://onlinelibrary.wiley.com/doi/10.1002/anie.202214191


7. Z. Zhou*, G. Roelfes*. "Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme"

   ACS Catalysis2021, 11, 9366. 

   Open Access https://pubs.acs.org/doi/10.1021/acscatal.1c02298



6. Z. Zhou, G. Roelfes*. "Synergistic catalysis in an artificial enzyme by simultaneous action of two abiological catalytic sites"

    Nature Catalysis2020, 3, 289. 

    https://www.nature.com/articles/s41929-019-0420-6

    News & Views by Nature Catalysishttps://www.nature.com/articles/s41929-020-0435-z

    (文章中文解读请见国内学术平台X-MOL头条报道:https://www.x-mol.com/news/158962)


                                               


5. Z. Zhou, Z. X. Wang, Q. Ouyang*, W. Du, Y.-C. Chen*.“Switchable regioselectivity in amine-catalysed asymmetric cycloadditions.” 

    Nature Chemistry2017, 9, 590. 

    https://www.nature.com/articles/nchem.2698

    Highlight by Synfacts 2017; 13, 0425. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1590093    

    (文章中文解读请见国内学术平台X-MOL头条报道:https://www.x-mol.com/news/4762)


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4. Z. Zhou,§ Q. He,§ Y. Jiang, W. Du, Y.-C. Chen*.“Double Thiol-Chiral Brønsted Base Catalysis: Asymmetric Cross Rauhut–Currier Reaction and Sequential [4 + 2] Annulation for Assembly of Different Activated Olefins”

  Organic Letters2019, 21, 7184. 

   (§equal contribution) https://pubs.acs.org/doi/10.1021/acs.orglett.9b02944


                                               

      

3. Z. Zhou, Z. X. Wang, Q. Ouyang, W. Xiao, W. Du, Y.-C. Chen*.“Cross-conjugated trienamine catalysis with alkylidene cyclic enones: application in regioselective aza-Diels Alder reaction.” 

   Chemistry - A European Journal2017, 23, 2945. 

   https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.201605606

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2. Z. Zhou, X. Feng, Y.-C. Chen*.“Direct remote asymmetric bisvinylogous 1,4-additions of cyclic 2,5-dienones to nitroalkenes.” 

   Organic Letters2014, 16, 2370. 

   https://pubs.acs.org/doi/10.1021/ol500700d


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1. X. Feng,§ Z. Zhou,§ C. Ma, X. Yin, L. Dong, Y.-C. Chen*. Trienamines Derived from Interrupted Cyclic 2,5-Dienones: Remote C=C Bond Activation for Asymmetric Inverse-Electron-Demand Aza-Diels Alder Reaction.”

   Angew. Chem. Int. Ed., 2013, 52, 14173. 

   (§equal contribution) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201307460


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参与作者代表性文章:


3. R. Leveson-Gower, Z. Zhou, I. Drienovská, G. Roelfes*. Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel-Crafts Alkylase. 

   ACS Catalysis, 2021, 11, 6763. 

   Open Access https://pubs.acs.org/doi/10.1021/acscatal.1c00996



2. L. Villarino*, S. Chordia, L. Alonso-Cotchico, E. Reddem, Z. Zhou, A. M. T. Thunnissen, J.-D. Maréchal, G. Roelfes*. Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme. 

   ACS Catalysis2020, 10, 11783. 

   https://pubs.acs.org/doi/10.1021/acscatal.0c01619


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1. X. Feng, Z. Zhou, R. Zhou, Q.-Q. Zhou, L. Dong, Y.-C. Chen*.“Stereodivergence in Amine-Catalyzed Regioselective [4 + 2] Cycloadditions of β-Substituted Cyclic Enones and Polyconjugated Malononitriles.”

   J. Am. Chem. Soc.2012,134, 19942. 

   https://pubs.acs.org/doi/10.1021/ja3106219