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Yadong Li Principle Investigator Unlock Sleep, Enhance Memory, Embrace Happiness
Yadong Li is a professor and Principal Investigator (PI) at the Shanghai Jiao Tong University School of Medicine. He earned his Ph.D. from Fudan University in 2018 under the mentorship of Dr. Zhili Huang. Subsequently, he pursued his postdoctoral training at the University of North Carolina at Chapel Hill under the guidance of Dr. Juan Song. In 2023, he established his own research laboratory at the Songjiang Research Institute, Shanghai Jiao Tong University School of Medicine. Yadong’s research focuses on elucidating how sleep-wake states intricately regulate memory in both health and disease. Yadong’s lab endeavors to dissect the neural circuits and cellular mechanisms underlying the influence of sleep/wake states on hippocampal-dependent memory consolidation and retrieval. Specifically, his research addresses the following questions: (1) How does sleep homeostasis impact spatial memory consolidation? (2) What are the effects of sleep-wake disorders on memory function in both healthy brains and Alzheimer’s disease? (3) How does chronic pain contribute to emotional and memory deficits?
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1. Neuronal circuits underly sleep-wake behaviors. 2. Circuit-modified adult hippocampal neurogenesis activity dependently regulates memory and emotion. 3. sleep disorders and cognitive deficits in in Alzheimer's disease. 4. Neurocircuit mechanisms of chronic pain-induced sleep disorders.
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