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成果及论文


2025


82. 

S. Zhong,+ S. Gan,+ X. Zhang,+ L. Song,* L. Shi*

Structurally Constrained Cyclic (Diacyloxyiodo)arenes as an Enabling Platform for Hypervalent iodine(III) Chemistry

Adv. Sci. 202512, 2506041.


81. 

P. Gong, L. Wang, C. Tian, S. Hao, L. Shi*

Pd-Catalyzed C(sp2)-P Cross-Coupling of Aryl Thianthrenium Salts

Chem. Eur. J. 202531(38), e202501060.


80.

 L. Wang,+ J. Yin,+ S. Gan, X. Yang, S. Hao, L. Shi*

Non-Covalent-Interaction-Dictated Product Selectivity in Intermolecular and Intramolecular Controllable Oxidation of Aromatic Amines Using 2,2’-Diperoxyphenic Acid

Adv. Synth. Catal. 2025367(14), e9598.



79. 

C. Tian, L. Shi*

Photoinduced Ring-Opening Functionalization of α-Imino-Oxy Acids and Alkanols Enabled by Phthalate-Derived Proton-Coupled Electron Transfer Mediator

Chin. J. Chem. 202543(16), 1988-1996.


78.

 C. Wei, K. Fu, Z. Yu, Z. Zhan, D. Chang, L. Shi*

Photochemical Generation and Cycloadditions of Strained Cycloallkynes

J. Am. Chem. Soc. 2025147(17), 14299-14307.


77.  

 H. Gao, X. Yang, L. Shi*

Asymmetric Oxidative Rearrangement of Indoles Enabled by Dual Catalysis with in situ Generated Acyl Hypoiodite and Chiral Phosphoric Acid

Org. Chem. Front. 202512(13), 3848-3855.


76. 

Z. Yu,+ Z. Zhan,+ K. Fu, L. Shi*

Intramoleculear and intermolecular benzannulation of arylethanone derivatives enabled by visible light-induced catalytic generation of tether-tunable distonic radical anions

Org. Chem. Front. 202512(12), 3568-3578.


75. 

S. Zhong, Z. Yu, Y. Zhu, L. Shi*

Catalytic Fluorination of α-Branched Ketones with Nucleophilic Fluorine

Org. Lett. 2025, 27(13), 3452-3458.


74. 

C. Wei, D. Chang, N. Feng, Z. Zhan, L. Shi*

A Unified Approach to Lactonization/Lactamization by Leveraging Tether-Tunable Distonic Radical Anions

Org. Lett. 2025, 27(11), 2582-2586.


73. 

C. Tian, L. Shi*

Photochemical generation of heteroatom (N, Si, B) or carbon radicals leveraging preinstalled carboxylic acids

Org. Chem. Front. 2025, 12(8), 2838-2859.


2024

72.    

T. Yuan, L. Shi*

Recent advances in carbon atom addition for ring-expanding single-atom skeletal editing

Org. Chem. Front. 202411(24), 7318-7332.


71. 

K. Fu, L. Shi*

Enabling Site-Selective C–H Functionalization of Aliphatic Alcohols and Amines with exo-Directing Groups by Tether-Tunable Design of PdII/PdIV Catalysis

ACS Catal. 202414(22), 17077-17083.


70.  

C. Tian, L. Shi*

Photoinduced cross-coupling of aryl halides enabled by n-tetrabutylphosphonium phthalate

Org. Chem. Front202411(23), 6718-6727.


69. 

K. Fu,+ X. Yang,+ Z. Yu, L. Song*, L. Shi*

Revealing the Nature of Covalently Tethered Distonic Radical Anions in the Generation of Heteroatom-Centered Radicals: Evidence for the Polarity-Matching PCET Pathway

Chem. Sci. 202415(31), 12398-12409.


68. 

T. Yuan, K. Fu, L. Shi*

Palladium(II)-Catalyzed Intramolecular C–H Amination to Carbazole: the Crucial Role of Cyclic Diacyl Peroxides

Org. Chem. Front. 202411(16), 4529-4538.


67.Two Catalytic Protocols for the Synthesis of CF2-Containing Quinazolinones via Domino Reaction

C. Wei, Z. Yu, L. Shi*

Two Catalytic Protocols for the Synthesis of CF2-Containing Quinazolinones via Domino Reaction

Adv. Synth. Catal. 2024366(14), 3181-3187.


66. 

X. Yang, H. Gao, J. Yan, J. Zhou*, L. Shi*

Intramolecular Chaperone-Assisted Dual-Anchoring Activation (ICDA): A Suitable Preorganization for Electrophilic Halocyclization

Chem. Sci. 202415(16), 6130-6140.


2023

65.  

J.-J. Yin, Y.-P. Wang, J. Xue, F.-F. Zhou, X.-Q. Shan, R. Zhu, K. Fang, L. Shi*, S.-Y. Zhang, S.-H. Hou*, W.-J. Xia, Y.-Q. Tu*

Total Synthesis of Polycyclic Diterpenes Phomopsene, Methyl Phomopsenonate, and iso-Phomopsene via Reorganization of C–C Single Bonds

J. Am. Chem. Soc. 2023145(39), 21170-21175.


64.

S. Gan, S. Zhong, L. Wang, L. Shi*

Synthesis and Application of Organic Hypervalent Bromine Reagents

有机高价溴试剂的合成及其应用研究

化学学报202381(8), 1030-1042.

Acta Chim. Sinica 202381(8), 1030-1042.


63.

Z. Zhan,+ J. Yan,+ Z. Yu, L. Shi*

Recent Advances in Asymmetric Catalysis Associated with B(C6F5)3

Molecules 202328(2), 642.


2022

62.

X.-H. Yang, H.-W. Gao, J. Yan and L. Shi*

Recent Progress in Radical-Mediated Si-H Functionalization of Silanes: An Effective Strategy for Synthesis of Organosilanes Containing C-Si Bond

自由基介导的硅烷Si-H 键官能团化研究进展:一种合成含C-Si键有机硅化合物的有效策略

Chin. J. Org. Chem. 202244, 106023/cjoc202207047.


61. 

Z. Yu and L. Shi*

Synthetic routes to bicyclo[1.1.1]pentylamines: booming toolkits for drug design

Org. Chem. Front. 20229(13), 3591-3597.


60. 

S. Gan, J. Yin, Z. Yu, L. Song* and L. Shi*

A one-pot and two-stage Baeyer-Villiger reaction using 2,2'-diperoxyphenic acid under biomolecule-compatible conditions

Green. Chem. 2022, 24(5), 2232-2239.


59.Image, graphical abstract

R. L.-Y. Bao, L. Shi* and K. Fu

Highly enantioselective construction of CF3-bearing all-carbon quaternary stereocenters: Chiral spiro-fused bisoxazoline ligands with 1,1'-binaphthyl sidearm for asymmetric Michael-type Friedel-Crafts reaction

Chin. Chem. Lett. 2022, 33(5), 2415-2419.


2021

58.                                                

X. Yang, D. Chang, R. Zhao and L. Shi*

Recent Advances and Uses of (Me4N)XCF3(X = S, Se) in theSynthesis of Trifluoromethylthiolated andTrifluoromethylselenolated Compounds 

Asian J. Org. Chem., 2021, 10(1), 61-73.



2020

57.                                                

R. Zhao, K. Fu, Y. Fang, J. Zhou* and L. Shi*

Site-Specific C(sp3)−H Aminations of Imidates and Amidines Enabled by Covalently Tethered Distonic Radical Anions 

Angew. Chem. Int. Ed., 2020, 59(46), 2068220690.



56.                                      

D. ZhuS. Gan, R. L.-Y. Bao and L. Shi* 

Copper-catalyzed cross-coupling of vinyliodonium salts and diboron reagents to generate alkenyl boronic esters

Org. Biomol. Chem., 2020, 18(29), 5567-5570.



55.                             

R. Zhao and L. Shi*

Reactions between Diazo Compounds and Hypervalent Iodine(III) Reagents

Angew. Chem. Int. Ed., 2020, 59(30), 12282–12292.




54                

R. L.-Y. Bao+, J. Yin+L. Shi* and L. Zheng

Rh(I)-Catalyzed enantioselective and scalable [4 + 2] cycloaddition of 1,3-dienes with dialkyl acetylenedicarboxylates

Org. Biomol. Chem., 2020, 18(15)2956-2961.



2019

53

L. Shi*R. L.‐Y. BaoL. Zheng and R. Zhao

B(C6F5)3‐Catalyzed Reduction of Cyclic N‐Sulfonyl Ketimines

Eur. J. Org. Chem., 2019, 2019(38), 6550–6556.

 

 

52.

Y. FangR. ZhaoY. YaoY. LiuD. ChangM. Yao and L. Shi*

Trichloroacetonitrile as an efficient activating agent for the ipso-hydroxylation of arylboronic acids to phenolic compounds

Org. Biomol. Chem., 2019, 17(32), 7558–7563.

 

 

2018

51.

R. Zhao and L. Shi*

A renaissance of ligand-to-metal charge transfer by cerium photocatalysis

Org. Chem. Front., 2018, 5(20), 3018-3021.

 

 

50.

D. Zhu and L. Shi*

Ni-catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents via C–S bond cleavage

Chem. Commun., 201854(67), 9313-9316.

 

 

49.

C. Wei, R. Zhao, Z. Shen, D. Chang and L. Shi*

Two Catalytic Protocols for Achmatowicz Rearrangement by Using Cyclic Diacyl Peroxides as Oxidants

Org. Biomol. Chem., 2018, 16(31), 5566-5569.

 

 

48.

D. Chang, F. Gao and L. Shi*

Potassium tert-butoxide-mediated generation of arynes from o-bromoacetophenone derivatives

Tetrahedron, 2018, 74(20), 2428-2434.

 

 

47.

Y. Zhang, L. He and L. Shi*

Asymmetric hydrogenolysis of racemic 3-substitued-3-hydroxy-isoindolin-1-ones employing SPINOL-derived chiral phosphoric acid

Tetrahedron Lett., 2018, 59(16), 1592-1595.

 

 

46.

Y. Zhang, L. He and L. Shi*

Chiral Ion-pair Organocatalyst Promoted Efficient Enantioselective Reduction of α-Hydroxy Ketones

Adv. Synth. Catal., 2018, 360(10), 1926-1931.

 

 

45.

D. Chang, R. Zhao, C. Wei, Y. Yao, Y. Liu and L. Shi*

Sulfonamide-Directed Chemo- and Site-Selective Oxidative Halogenation/Amination Using Halogenating Reagents Generated in situ from Cyclic Diacyl Peroxides

J. Org. Chem., 2018, 83(6), 3305-3315.

 

 

44.

D. Zhu, Y. Yao, R. Zhao, Y. Liu and L. Shi*

Metal-Free Geminal Difunctionalization of Diazocarbonyl Compounds: A One-Pot Multicomponent Strategy for the Construction of α,β-Diamino Carbonyl Derivatives

Chem. Eur. J., 2018, 24(19), 4805-4809.

 

 

43.

F. Ding, Y. Jiang, K. Lin and L. Shi*

Tandem radical cyclization for the construction of 1-difluoroalkylated isoquinolines via Cu catalyzed and visible light-promoted pathways

Org. Biomol. Chem., 2018, 16(11), 1812-1815.

 

 

42.

F. Ding, Y. Fang, Y. Jiang, K. Lin and L. Shi*

Tandem Radical Cyclization for the Construction of Difluoro-Containing Oxindoles and Quinoline-2,4-diones

Chem. Asia. J., 201813(6), 636-640.

 

 

41.

R. Zhao+, Y. Yao+, D. Zhu, D. Chang, Y. Liu and L. Shi*

Visible-Light-Enhanced Ring Opening of Cycloalkanols Enabled by  Bronsted Base-Tethered Acyloxy Radical Induced Hydrogen Atom Transfer-Electron Transfer

Org. Lett., 2018, 20(4), 1228-1231.

 

 

2017

40.   

F. Ding, Y. Zhang, R. Zhao, Y. Jiang, R. L.-Y. Bao, K. Lin and L. Shi*

B(C6F5)3-promoted hydrogenations of N-heterocycles with ammonia borane

Chem. Commun., 2017, 53(66), 9262-9264. 

 

 

39.

Y. Zhang, Y. Yao, L. He, Y. Liu and L. Shi*

Rhodium(II)/Chiral Phosphoric Acid Co-Catalyzed Enantioselective O–H Bond Insertion of α-Diazoesters (as VIP)

Adv. Synth. Catal., 2017, 359(16), 2754-2761.

 

 

38.

R. Zhao, D. Chang and L. Shi*

Recent Advances in Cyclic Diacyl Peroxides: Reactivity and Selectivity Enhancement Brought by Cyclic Structure

Synthesis., 2017, 49(15), 3357-3365. 

 

 

37.

F. Ding, Y. Jiang, S. Gan, R. L.-Y. Bao, K. Lin and L. Shi*

B(C6F5)3-Catalyzed Deoxygenation of Sulfoxides and Amine N-Oxides with Hydrosilanes

Eur. J. Org. Chem., 2017, 2017(24), 3427-3430.

 

 

36.

S. Gan, J. Yin, Y. Yao, Y. Liu, D. Chang, D. Zhu and L. Shi*

Metal- and additive-free oxygen-atom transfer reaction: an efficient and chemoselective oxidation of sulfides to sulfoxides with cyclic diacyl peroxides

Org. Biomol. Chem., 2017, 15(12), 2647-2654.

 

 

2016

35.  

D. Zhu, D. Chang, S. Gan and L. Shi*

Direct α-acyloxylation of organic sulfides with the hypervalent (diacyloxyiodo)benzene/tetra-n-butylammonium bromide (TBAB) reagent combination

RSC Adv., 2016, 6(33), 27983-27987.

 

2015

34.

D. Chang, D. Zhu and L. Shi*

[3+2] Cycloadditions of Azides with Arynes via Photolysis of Phthaloyl Peroxide Derivatives

J. Org. Chem., 2015, 80(11), 5928-5933.

 

 

33.

S. Kong, L. Zhang, X. Dai, L. Tao, C. Xie, L. Shi* and M. Wang*

DDQ-mediated Direct C(sp3)-H Cyanation of Benzyl Ethers and 1,3-Diarylpropenes under Solvent- and Metal-free Conditions

Adv. Synth. Catal., 2015, 357(11), 2453-2456.

 

 

32.

Y. Zhang, R. Zhao, R. L.-Y. Bao and L. Shi*

Highly Enantioselective SPINOL-Derived Phosphoric Acid Catalyzed Transfer Hydrogenation of Diverse C=N-Containing Heterocycles

Eur. J. Org. Chem., 2015, 2015(15), 3344-3351.

 

 

31.

D. Zhu, D. Chang and L. Shi*

Transition-metal-free cross-coupling of thioethers with aryl(cyano)iodonium triflates: a facile and efficient method for the one-pot synthesis of thiocyanates

Chem. Commun., 2015, 51(33), 7180-7183.

 

 

30.

 R. L.-Y. Bao, R. Zhao and L. Shi*

Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl: a ten-year journey

Chem. Commun., 2015, 51(32), 6884-6900.

 

 

29.

D. Chang, D. Zhu, P. Zou and L. Shi*

Cleavage of C-N bonds in guanidine derivatives and its relevance to efficient C-N bonds formation

Tetrahedron, 2015, 71(11), 1684-1693.

 

 

2014

28.  

R. Zhao and L. Shi*

Promising Combination for Asymmetric Organocatalysis: Bronsted Acid-Assisted Chiral Phosphoric Acid Catalysis

ChemCatChem., 2014, 6(12), 3309-3311.