Wang S, Yang W, Peng T, Zhu C, Dong J, Wang Y, Yuan H, Sun Q, Luan X, Guan X*, Zhang W*, Qin JJ*. IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer. Nature Communications 2025 Nov 28;16(1):10733. doi: 10.1038/s41467-025-65762-4.

Li S#, Yuan L#, Xu ZY, Xu JL, Chen GP, Guan X, Pan GZ, Jiang RB, Zhu X, Lv H, Xu HD, Hu C, Zhang SJ, Dong J, Qin JJ*, Cheng XD*. Integrated proteogenomic characterization of adenocarcinoma of esophagogastric junction. Nature Communications 2023; 14:778. https://doi.org/10.1038/s41467-023-36462-8

Cheng X#, Dai E#, Wu J#, Flores NM, Chu Y, Wang R, Dang M, Xu Z, Han G, Liu H, Chatterjee D, Hu C, Ying J, Du Y, Yang L, Guan X, Mo S, Cao X, Pei G, Jiang J, Lu X, Benitez AM, Waters RE, Pizzi MP, Shanbhag N, Fan Y, Peng F, Hanash SM, Calin G, Futreal A, Song S, Yee C, Mazur PK*, Qin JJ*, Ajani JA*, Wang L*. Atlas of metastatic gastric cancer links ferroptosis to disease progression and immunotherapy response. Gastroenterology 2024; 167(7): 1345–1357. https://doi.org/10.1053/j.gastro.2024.07.038

Li G#, Jiang Y#, Tong H#,  Liu J#, Jiang Z, Zhao Y, Tan K, Zhang Y, Yin X, Yun H, He Y, Liao H*, Qin JJ*, Ma X*. Sciatic nerve stimulation enhances NK cell cytotoxicity through dopamine signaling and synergizes immunotherapy in triple-negative breast cancer. Drug Resistance Updates 2025,79:101212. https://doi.org/10.1016/j.drup.2025.101212 

Guan X#, Wang Y#, Yu W, Wei Y, Lu Y, Dai E, Dong X, Zhao B, Hu C, Yuan L, Luan X, Miao K, Chen B, Cheng XD*, Zhang W*, Qin JJ*. Blocking Ubiquitin-Specific Protease 7 Induces Ferroptosis in Gastric Cancer via Targeting Stearoyl-CoA Desaturase. Advanced Science 2024; 11(18):e2307899. http://doi.org/10.1002/advs.202307899

Dong J, Ma F, Cai M, Cao F, Li H, Liang H, Li Y, Ding G, Li J, Cheng XD*, Qin JJ*. Heat Shock Protein 90 Interactome-Mediated Proteolysis Targeting Chimera (HIM-PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis. Journal of Medicinal Chemistry 2024; 67(18):16712-16736. https://doi.org/10.1021/acs.jmedchem.4c01518

Wang R#, Song S#, Qin JJ#, Yoshimura K, Peng F, Chu Y, Li Y, Fan Y, Jin J, Dang M, Dai E, Pei G, Han G, Hao D, Li Y, Chatterjee D, Harada K, Pizzi MP, Scott AW, Tatlonghari G, Yan X, Xu Z, Hu C, Mo S, Shanbhag N, Lu Y, Sewastjanow-Silva M, Abdelhakeem AAF, Peng G, Hanash SM, Calin GA, Yee C, Mazur PK, Marsden AN, Futreal A, Wang Z, Cheng XD, Ajani JA*, Wang L*. Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression. Cancer Cell 2023; 41(8):1407-1426.e9. https://doi.org/10.1016/j.ccell.2023.06.005

Guan X#, Yang J#, Wang W#,*, Zhao B, Hu S, Yu D, Yuan L, Shi F, Xu J, Dong J, Wang J, Cheng X*, Qin JJ*. Dual inhibition of MYC and SLC39A10 by a novel natural product STAT3 inhibitor derived from Chaetomium globosum suppresses tumor growth and metastasis in gastric cancer. Pharmacological Research 2023; 189: 106703. https://doi.org/10.1016/j.phrs.2023.106703

Dong J*, Yuan L, Hu C, Cheng X*, Qin JJ*. Strategies to overcome cancer multidrug resistance (MDR) through targeting P-glycoprotein (ABCB1): an updated review. Pharmacology & Therapeutics 2023, 249: 108488.

Qi S#, Guan X#, Zhang J#, Yu D, Yu X, Li Q, Yin W, Cheng XD*, Zhang WD*, Qin JJ*. Targeting E2 ubiquitin-conjugating enzyme UbcH5c by small molecule inhibitor suppresses pancreatic cancer growth and metastasis. Molecular Cancer 2022; 21:70. https://doi.org/10.1186/s12943-022-01538-4

Zhu C#, Guan X#, Zhang X#, Luan X, Song Z, Cheng XD*, Zhang WD*, Qin JJ*. Targeting KRAS mutant cancers: From druggable therapy to drug resistance. Molecular Cancer 2022; 21:159. https://doi.org/10.1186/s12943-022-01629-2

Li H#, Dong J#,*, Cai M, Xu ZY, Cheng XD*, Qin JJ*. Protein degradation technology: A strategic paradigm shift in drug discovery. Journal of Hematology & Oncology 2021; 14:138. https://doi.org/10.1186/s13045-021-01146-7

Dong JY, Cheng XD, Zhang WD, Qin JJ*. Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation. Journal of Medicinal Chemistry 2021; 64(13): 8884-8915. doi: 10.1021/acs.jmedchem.1c00629.

Dong J#, Qin Z#, Zhang WD, Cheng G, Yehuda AG, Ashby CR Jr, Chen ZS*, Cheng XD*, Qin JJ*. Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update. Drug Resistance Updates 2020; 49:100681. doi: 10.1016/j.drup.2020.100681.