(33) Synthesis of Unsymmetrical Disulfides via Photocatalytic Hydrodisulfuration
Qi-Rui Dong, Yi-Sen Wang, Juan Zhang, Hong-Hong Chang, Jun Tian, Wen-Chao Gao*
ACS Catalysis, 2024, 14, 18237−18246. （工作亮点介绍：有趣的有机合成；化学深耕堂；邃瞳科学云；CBG资讯; 言之成理）
(32) Structure-guided design and photochemical synthesis of new carbamo(dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CLpro
De-Hang Yin, Jie Xin, Shizhao Chen, Shuai-Shuai Li , Zi-Ying Li , Jin-Xi Meng, Yue-Chi Lin, Bing-Qian Yin, Cheng Zhao, Jia Li, Hang Gao,* Jun Tian, Wen-Chao Gao*
Bioorganic & Medicinal Chemistry, 2024, 114, 11790.
(31) Radical Alkynylthiolation with Visible-Light-Sensitive S-Alkynylthio Sulfonates
Yaonan Xue, Qirui Dong, Jiarui Chen, Hang Gao, Honghong Chang, Jun Tian, Wen-Chao Gao*
Org.Lett. 2024, 26, 6966–6971.
(30) Mild and green thioacylation with dithiocarboxylates via photoredox catalysis
Wen-Chao Gao,* Wei Li, Juan Zhang, Hong-Hong Chang, Rong Zhou*
Green Synth. Catal. 2024, 10.1016/j.gresc.2024.02.008 （Highlighted by 化学深耕堂）
(29) N-Vinylthio Phthalimides (N-VTPs): Modular Reagents for Vinylthio AIEgen Transfer
Wen-Chao Gao*, Jing Fan, Ya-Feng Wei, Juan Zhang, Hong-Hong Chang, and Jun Tian*
Org.Lett. 2024, 26, 78-83 (Highlighted in CBG资讯)
(28) Construction of alkynyl and acyl disulfides directly through thiol-modification with N-alkynylthio phthalimides under acid catalysis
Yao-Nan Xue, Kai Feng, Jun Tian, Juan Zhang, Hong-Hong Chang and Wen-Chao Gao*
Org. Chem. Front. 2023, 10 , 2070-2074. （Highlighted by 化学深耕堂）
(27) N-Acetylenethio phthalimides: sequential linkage for compositional click reaction
Wen-Chao Gao,* Kai Feng, Jun Tian, Juan Zhang, Hong-Hong Chang, Xuefeng Jiang*
Chin.Chem. Lett. 2023, 34, 107587. (Highlighted by CBG)
(26) N-Thiohydroxy Succinimide Esters (NTSEs)：Versatile Reagents for Selective Acyl and Acylthio Transfer
Yun-Feng Li, Ya-Feng Wei, Jun Tian, Juan Zhang, Hong-Hong Chang, and Wen-Chao Gao*
Org. Lett. 2022, 24, 5736-5740. (Highlited by CBG and Organic Chemistry Portal)
(25) Recent Advances in thiolation via sulfur electrophiles
Ya-Feng Wei, Wen-Chao Gao,* Hong-Hong Chang and Xuefeng Jiang *
Org. Chem. Front. 2022, 9, 6684-6707.
(24) 3,4-Bisthiolated Pyrroles: Concise Construction and Their Electronic Properties
Jun Tian, Kai Feng, Kang-Ning Yuan, Xing Li, Hong-Hong Chang, and Wen-Chao Gao*
J. Org. Chem. 2022, 87, 2402–2409.
(23) Homocouplings of Sodium Arenesulfinates: Selective Access to Symmetric Diaryl Sulfides and Diaryl Disulfides
Xin-Zhang Yu,Wen-Long Wei,Yu-Lan Niu,* Xing Li, Ming Wang, and Wen-Chao Gao*
Molecules 2022, 27, 6232. (invited contribution to Special issue: Catalysis for Green Chemistry)
(22) 3-Thiolated pyrroles/pyrrolines: controllable synthesis and usage for the construction of thiolated fluorophores
Jun Tian,‡ Kang-Ning Yuan,‡ Wen Liu, Hong-Hong Chang, Xing Li, and Wen-Chao Gao*
Chem. Commun. 2021, 57, 1943-1946. (Highlight by Synfacts 2021, 17, 0512.)
(21) Phthalimide-Based-SSCF3 Reagent for Enantioselective Dithiotrifluoromethylation
Wen-Chao Gao, J. Liu, and X. Jiang*
Org. Chem. Front. 2021, 8, 1275-1279. (Highlighted by Frontiers Journals)
(20) Rh(I)-Catalyzed Carbene Migration/Carbonylation/Cyclization: Straightforward Construction of Fully Substituted Aryne Precursors.
Guohao Zhu, Wen-Chao Gao, Xuefeng Jiang*
J. Am. Chem. Soc. 2021, 143, 1334-1340. (Highlighted by X-Mol.)
(19) Steric and Stereoscopic Disulfide Construction for Cross-linkage via N-Dithiophthalimides.
Wen-Chao Gao, Jun Tian, Yuzhu Shang and Xuefeng Jiang*
Chem. Sci. 2020, 11, 3903-3908. (Highlighted by X-Mol.)
(18) Chemo- and Diastereoselective Synthesis of Pyrrolidines from Aroylformates and δ-Tosylamino Enones
via P(NMe2)3-Mediated Reductive Amination/Base-Catalyzed Michael Addition Cascade
Rongfang Liu, Jialin Liu, Jilei Cao, Ruifeng Li, Rong Zhou*, Yan Qiao, and Wen-Chao Gao*
Org. Lett. 2020, 22, 6922–6926.
(17) Synthesis of 4-chalcogenyl pyrazoles via electrophilic chalcogenation/cyclization of α,β-alkynic hydrazones.
Xinzhang Yu, Yu-Zhu Shang, Yu-Fei Cheng, Jun Tian, Yulan Niu* and Wen-Chao Gao*
Org. Biomol. Chem. 2020, 18, 1806–1811.
(16) N‑Alkynylthio Phthalimide: A Shelf-Stable Alkynylthio Transfer Reagent for the Synthesis of Alkynyl Thioethers.
Wen-Chao Gao,* Yu-Zhu Shang, Hong-Hong Chang, Xing Li, Wen-Long Wei, Xin-Zhang Yu, and Rong Zhou*
Org. Lett., 2019, 21(15): 6021−6024.
(15) Synthesis of 4-Sulfenyl Isoxazoles through AlCl3-Mediated Electrophilic Cyclization and Sulfenylation of
2-Alkyn-1-one O-Methyloximes.
Wen-Chao Gao*, Yu-Fei Cheng, Hong-Hong Chang, Xing Li, Wen-Long Wei, and Peng Yang*
J. Org. Chem. 2019, 84 (7): 4312-4317.
(14) Enantioselective Electrochemical Lactonization Using Chiral Iodoarenes as Mediators.
Wen-Chao Gao, Zi-Yue Xiong, Shafigh Pirhaghani, Thomas Wirth*
(13) Copper(II)-Catalyzed Four-Component Oxysulfonylation/Diazenylation: Synthesis of α-Arylhydrazo-β-keto Sulfones.
Wen-Chao Gao,* Yu-Fei Cheng, Yu-Zhu Shang, Hong-Hong Chang, Xing Li, Rong Zhou,* Yan Qiao, and Wen-Long Wei
J. Org. Chem. 2018, 83(19): 11956-11962.
(12) Chemoselective P(NMe2)3‑Mediated Reductive Epoxidation between Two Different Carbonyl Electrophiles: Synthesis of
Highly Functionalized Unsymmetrical Epoxides.
Rong Zhou,* Honghui Zhang, Jialin Liu, Rongfang Liu, Wen-Chao Gao,* Yan Qiao, and Ruifeng Li
J. Org. Chem. 2018, 83, 8272−8280.
(11) AlCl3-Catalyzed Intramolecular Cyclization of N-Arylpropynamides with N-Sulfanylsuccinimides: Divergent Synthesis of 3-Sulfenyl Quinolin-2-ones and Azaspiro[4,5]trienones.
Wen-Chao Gao,* Tao Liu, Yu-Fei Cheng, Hong-Hong Chang, Xing Li, Rong Zhou,* Wen-Long Wei, and Yan Qiao,
J. Org. Chem. 2017, 82, 13459−13467.
(10) Intermolecular sulfenoamination of alkenes with sulfonamides and N-sulfanylsuccinimides to access β-sulfonylamino sulfides and dihydrobenzothiazines.
Tao Liu, Jun Tian, Wen-Chao Gao,* Hong-Hong Chang, Qiang Liu,* Xing Li, and Wen-Long Wei
Org. Biomol. Chem. 2017, 15, 5983-5992.
(9) Metal-free formal carbon–halogen bond insertion: facile syntheses of 3-halo 3,3’-disubstituted oxindoles and spirooxindole-g-butyrolactones.
Rong Zhou,* Rongfang Liu, Kai Zhang, Ling Han, Honghui Zhang, Wen-chao Gao* and Ruifeng Li
Chem. Commun. 2017, 53, 6860-6863.
(8) Hypoiodite-catalysed oxidative cyclisation of Michael adducts of chalcones with 1,3-dicarbonyl compounds: a facile and versatile approach to substituted furans and cyclopropanes.
Wen-Chao Gao,* Fei Hu, Jun Tian, Xing Li, Wen-Long Wei, Hong-Hong Chang*
Chem. Commun. 2016, 52, 13097-13100.
(7) Synthesis of 3-sulfenylated coumarins: BF3·Et2O-mediated electrophilic cyclization of aryl alkynoates using N-sulfanylsuccinimides.
Wen-Chao Gao, Tao Liu, Bing Zhang, Xing Li, Wen-Long Wei, Qiang Liu, Jun Tian,* Hong-Hong Chang*
J. Org. Chem. 2016, 81, 11297-11304.
(6) Iodine-Mediated Oxidative Dehydrogenation of β-Acylamino Ketones for the Highly Stereoselective Synthesis of (Z)-β-Ketoenamides.
Hong-Hong Chang, Fei Hu, Wen-Chao Gao,* Tao Liu, Xing Li, Wen-Long Wei, Yan Qiao*
Synlett 2016, 27, 1592-1596.
(5) I2-catalyzed C-O bond formation and dehydrogenation: facile synthesis of oxazolines and oxazoles controled by bases.
Wen-Chao Gao,* Fei Hu, Hong-Hong Chang,* Xing Li and Wen-Long Wei
Org. Lett. 2015, 17, 3914-3917. (Highlighted by X-mol & Organic Chemistry Portal )
(4) I2-mediated sulfonylation and Na2SO3-mediated deacylation: a general protocol for the synthesis of beta-keto sulfones and beta-dicarbonyl sulfones.
Wen-Chao Gao,* Jin-Jin Zhao, Fei Hu, Hong-Hong Chang,* Xing Li and Wen-Long Wei
RSC Adv. 2015, 5, 25222-25228.
(3) Iodine-catalysed sp3 C-H sulfonylation to form beta-dicarbonyl sulfones with sodium sulfinates.
Wen-Chao Gao,* Jin-Jin Zhao, Hong-Hong Chang,* Xing Li, Qiang Liu, and Wen-Long Wei
RSC Adv. 2014, 4, 49329-49332.
(2) Iodine-mediated intramolecular amination of ketones: the synthesis of 2-acylindoles and 2-acylindolines by tuning N-protecting groups.
Wen-Chao Gao, Shan Jiang, Ruo-Lin Wang and Chi Zhang*
Chem. Commun. 2013, 49, 4890-4892. (Prior to TYUT)
(1) Practical oxazole synthesis mediated by iodine from α-bromoketones and benzylamine derivatives.
Wen-Chao Gao, Ruo-Lin Wang and Chi Zhang*
Org. Biomol. Chem. 2013, 11, 7123-7128. (Prior to TYUT)
中文综述与科普：
(15) 田俊，高晨曦，高文超，*跨界药王——司美格鲁肽的进阶之旅. 洞察化学，2025（网络阅读量破万，科普大赛一等奖，最佳人气奖）（转载：化学加，化学深耕堂）
(14) 李紫瑛,冯思越,李帅帅,高文超,* 高粱历险记之酒的诞生. 化学通讯，2024，1，11-16.（第三届“全民科普”科普作品大赛一等奖）视频创作（高粱与白酒的故事）
(13) 尹德航，黄婧彤，李佳乐，冯思越，彭静怡，赵成，高文超.* 临床阶段及已批准上市新型冠状病毒3CL蛋白酶抑制剂的研究进展。中国药物化学杂志，2023，33，540-550.
(12)李云峰，辛杰，李静，常宏宏，高文超.* 抗体偶联药物中连接技术研究进展，中国新药与临床. 2022,41, 719-728(Highligted in 抗体圈)
(11) 尹德航，高文超.* 厨房的味道——醋是陈的香. 化学通讯，2023,34-40.(Highlighted in 甘肃省科学技术协会)
(10) 尹德航，施乐洋，叶雨涵，陈丹，王郅炫，高文超.* 天然产物及其有效成分在化妆品领域的研究与开发[J]. 化学试剂，2022，44(7): 960-967.(中国知网高下载论文)
(9) 高文超, 姜雪峰.* 中国化学家在2021年诺贝尔化学奖领域的贡献[J]. 自然杂志, 2021, 43(6): 430-440.
(8)冯凯, 辛杰, 田俊, 常宏宏, 高文超,* 天然抗生素结构与构效关系研究进展[J]. 中国抗生素杂志，2021，46（9），802-820.
(7) 田俊, 高文超,* 姜雪峰,* 分子噻蒽化修饰及偶联反应研究进展[J].化学试剂，2021,43(4): 447-453.
(6) 袁康宁, 赵玉英, 常宏宏, 田俊, 高文超,* AlCl3促进的有机反应研究进展[J]. 有机化学，2020, 40, 2607-2625。
(5) 高文超，田俊，姜雪峰,* 味觉化学之辣味化学[J]，化学教育, 2020, 41, 1-6.（Highlighted in 返朴）
(4) 高文超，田俊，姜雪峰,* 味觉化学之鲜味化学[J]. 化学教育, 2020, 41, 1-7.
(3) 高文超，姜雪峰,*几种杂原子元素在天然药物分子库中的形式和意义[J]. 化学试剂, 2020, 42, 1-7.
(2) 胡飞, 高文超,* 常宏宏,* 李兴,魏文珑, 碘促进的砜基化反应研究进展[J]. 有机化学，2015, 35, 1848-1860.
(1) 赵巾巾, 高文超,* 常宏宏,* 李兴, 刘强, 魏文珑, 单质碘促进的有机反应研究进展[J]. 有机化学，2014, 34, 1941-1957.
授权专利：
(1) 高文超，常宏宏，赵巾巾，李兴，刘强，魏文珑.一种β-二羰基砜类化合物及其制备方法。专利授权号：ZL 2014 1 0454957.3
(2) 高文超，田俊，常宏宏，李兴，魏文珑.一种采用1,3-二酮类化合物合成α-取代酮的方法。专利授权号：ZL 2015 1 0003993.2
(3) 高文超，田俊，常宏宏，胡飞，李兴，魏文珑.一种多取代吡啶的制备方法。专利授权号：ZL 2016 1 1233946.8
(4) 田俊，高文超，常宏宏，李兴，魏文珑.一种四元杂环苯并噻吩并喹啉化合物及其制备方法。专利授权号：ZL 2017 1 0601929.3
(5) 高文超，程宇飞，常宏宏，李兴，魏文珑.一种3-硫代-2,3-二氢喹啉-4(1H)-酮类化合物的合成方法。专利授权号：ZL 2018 1 0750392.1
(6）高文超，尚玉柱，田俊，常宏宏.一种N-炔硫基邻苯二甲酰亚胺类化合物的制备方法。专利授权号：ZL 2019 1 0440132.9.
(7) 姜雪峰，高文超.立体和大位阻二硫醚化合物及其合成方法和应用。专利授权号：ZL 2020 1 0185510.6
(8) 高文超，田俊,常宏宏，袁康宁.一种3-硫代吡咯啉化合物及其合成方法。专利授权号：ZL 2020 1 1191032.6
(9) 高文超，田俊,常宏宏，袁康宁.一种3-硫代吡咯化合物及其合成方法。专利授权号：ZL 2020 1 1195870.0
(10) 高文超，田俊,常宏宏，张娟.一种3,4-双硫代吡咯材料的制备方法.专利授权号：ZL 2021 1 1126551.9.
(11)高文超,薛耀楠,田俊,尹德航,常宏宏.一种无溶剂重排反应合成酰基二硫化合物的方法. 专利授权号：ZL 2023 1 0139248.5.
书籍著作：
Wen-Chao Gao and Jun Tian, Science of Synthesis Knowledge Updates, 2020, Chapter 14.4.16-14.4.20