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热烈祝贺李尚在JMC报道靶向MLKL的共价键降解剂
发布时间:2024-08-25

Shang Li, Liangliang Ma, Xinxin Li, Yuhan Jiang, Zhongwen Luo, Fucheng Yin, Yonglei Zhang, Yifan Chen, Siyuan Wan, Han Zhou, Lingyi Kong*, Xiaobing Wang*, Discovery of Covalent MLKL PROTAC Degraders via Optimization of a Theophylline Derivative Ligand for Treating NecroptosisJournal of Medicinal Chemistry2024, 67, 17, 15353–15372, DOI: 10.1021/acs.jmedchem.4c00949